Targeted next-generation sequencing of dedifferentiated chondrosarcoma in the skull base reveals combined TP53 and PTEN mutations with increased proliferation index, an implication for pathogenesis

Authors

Lu Gao, Chinese Academy of Medical Sciences and Peking Union Medical College
Xiafei Hong, Chinese Academy of Medical Sciences and Peking Union Medical College
Xiaopeng Guo, Chinese Academy of Medical Sciences and Peking Union Medical College
Dengfeng Cao, Washington University School of Medicine in St. Louis
Xiaohuan Gao, Binhai Genomics Institute
Thomas F. DeLaney, Harvard Medical School
Xinqi Gong, Renmin University of China
Rongrong Chen, Chinese Academy of Medical Sciences and Peking Union Medical College
Jianjiao Ni, Chinese Academy of Medical Sciences and Peking Union Medical College
Yong Yao, Chinese Academy of Medical Sciences and Peking Union Medical College
Renzhi Wang, Chinese Academy of Medical Sciences and Peking Union Medical College
Xi Chen, Tianjin Translational Genomics Center
Pangzehuan Tian, Binhai Genomics Institute
Bing Xing, Chinese Academy of Medical Sciences and Peking Union Medical College

Journal

Oncotarget

Publication Date

2016

Volume

7

Issue

28

Inclusive Pages

43557-43569

Document Type

Open Access Publication

DOI

10.18632/oncotarget.9618

Rights and Permissions

Gao, L., Hong, X., Guo, X., Cao, D., Gao, X., DeLaney, T. F., . . . Xing, B. (2016). Targeted next-generation sequencing of dedifferentiated chondrosarcoma in the skull base reveals combined TP53 and PTEN mutations with increased proliferation index, an implication for pathogenesis. Oncotarget, 7(28), 43557-43569. doi:10.18632/oncotarget.9618. Copyright: © Gao et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Recommended Citation

Gao, Lu; Hong, Xiafei; Guo, Xiaopeng; Cao, Dengfeng; Gao, Xiaohuan; DeLaney, Thomas F.; Gong, Xinqi; Chen, Rongrong; Ni, Jianjiao; Yao, Yong; Wang, Renzhi; Chen, Xi; Tian, Pangzehuan; and Xing, Bing, "Targeted next-generation sequencing of dedifferentiated chondrosarcoma in the skull base reveals combined TP53 and PTEN mutations with increased proliferation index, an implication for pathogenesis." Oncotarget. 7, 28. 43557-43569. (2016).
https://digitalcommons.wustl.edu/open_access_pubs/6457