Consumption of NADPH for 2-HG synthesis increases pentose phosphate pathway flux and sensitizes cells to oxidative stress

Authors

Susan J. Gelman, Washington University in St. Louis
Fuad Naser, Washington University in St. Louis
Nathaniel G. Mahieu, Washington University in St. Louis
Lisa D. McKenzie, Washington University School of Medicine in St. Louis
Gavin P. Dunn, Washington University School of Medicine in St. Louis
Milan G. Chheda, Washington University School of Medicine in St. Louis
Gary J. Patti, Washington University School of Medicine in St. Louis

Journal

Cell reports

Publication Date

2018

Volume

22

Issue

2

Inclusive Pages

512-522

Document Type

Open Access Publication

DOI

10.1016/j.celrep.2017.12.050

Rights and Permissions

Gelman SJ, Naser F, Mahieu NG, McKenzie LD, Dunn GP, Chheda MG, Patti GJ (2018) Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress. Cell Reports, 22(2): 512-522. https://doi.org/10.1016/j.celrep.2017.12.050 Copyright 2017 The Author(s). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Recommended Citation

Gelman, Susan J.; Naser, Fuad; Mahieu, Nathaniel G.; McKenzie, Lisa D.; Dunn, Gavin P.; Chheda, Milan G.; and Patti, Gary J., "Consumption of NADPH for 2-HG synthesis increases pentose phosphate pathway flux and sensitizes cells to oxidative stress." Cell reports. 22, 2. 512-522. (2018).
https://digitalcommons.wustl.edu/open_access_pubs/6630