Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice

Authors

Sathyaseelan S. Deepa, Oklahoma Medical Research Foundation
Gavin Pharaoh, University of Oklahoma Health Sciences Center
Michael Kinter, Oklahoma Medical Research Foundation
Vivian Diaz, University of Texas Health Science Center at San Antonio
Wilson C. Fok, Washington University School of Medicine in St. Louis
Kaitlyn Riddle, Oklahoma Medical Research Foundation
Daniel Pulliam, University of Texas Health Science Center at San Antonio
Shauna Hill, University of Texas Health Science Center at San Antonio
Kathleen E. Fischer, University of Alabama, Birmingham
Vanessa Soto, University of Texas Health Science Center at San Antonio
Constantin Georgescu, Oklahoma Medical Research Foundation
Jonathan D. Wren, Oklahoma Medical Research Foundation
Carlo Viscomi, University of Cambridge
Arlan Richardson, University of Oklahoma Health Sciences Center
Holly Van Remmen, University of Oklahoma Health Sciences Center

Journal

Aging Cell

Publication Date

2018

Volume

17

Issue

4

Inclusive Pages

e12769

Document Type

Open Access Publication

DOI

10.1111/acel.12769

Rights and Permissions

Deepa SS, Pharaoh G, Kinter M, et al (2018) Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. Aging Cell, 17(4):e12769. https://doi.org/10.1111/acel.12769 This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2018 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

Recommended Citation

Deepa, Sathyaseelan S.; Pharaoh, Gavin; Kinter, Michael; Diaz, Vivian; Fok, Wilson C.; Riddle, Kaitlyn; Pulliam, Daniel; Hill, Shauna; Fischer, Kathleen E.; Soto, Vanessa; Georgescu, Constantin; Wren, Jonathan D.; Viscomi, Carlo; Richardson, Arlan; and Van Remmen, Holly, "Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice." Aging Cell. 17, 4. e12769. (2018).
https://digitalcommons.wustl.edu/open_access_pubs/7027