The widely used antimicrobial triclosan induces high levels of antibiotic tolerance in vitro and reduces antibiotic efficacy up to 100-fold in vivo

Authors

Corey Westfall, Washington University in St. Louis
Ana Lidia Flores-Mireles, Washington University School of Medicine in St. Louis
John Isaac Robinson, Washington University School of Medicine in St. Louis
Aaron J.L. Lynch, Washington University School of Medicine in St. Louis
Scott Hultgren, Washington University School of Medicine in St. Louis
Jeffrey P. Henderson, Washington University School of Medicine in St. Louis
Petra Anne Levin, Washington University in St. Louis

Journal

Antimicrobial agents and chemotherapy

Publication Date

2019

Volume

63

Issue

5

Inclusive Pages

e02312-18

Document Type

Open Access Publication

DOI

10.1128/AAC.02312-18

Rights and Permissions

Westfall C, Flores-Mireles AL, Robinson JI, Lynch AJL, Hultgren S, Henderson JP, Levin PA. 2019. The widely used antimicrobial triclosan induces high levels of antibiotic tolerance in vitro and reduces antibiotic efficacy up to 100-fold in vivo. Antimicrob Agents Chemother 63:e02312-18. https://doi.org/10.1128/AAC.02312-18. Copyright © 2019 Westfall et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Recommended Citation

Westfall, Corey; Flores-Mireles, Ana Lidia; Robinson, John Isaac; Lynch, Aaron J.L.; Hultgren, Scott; Henderson, Jeffrey P.; and Levin, Petra Anne, "The widely used antimicrobial triclosan induces high levels of antibiotic tolerance in vitro and reduces antibiotic efficacy up to 100-fold in vivo." Antimicrobial agents and chemotherapy. 63, 5. e02312-18. (2019).
https://digitalcommons.wustl.edu/open_access_pubs/7741