Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

Authors

Deborah A. Roby, Saint Louis University
Fernanda Ruiz, Saint Louis University
Bailey A. Kermath, Saint Louis University
Jaymie R. Voorhees, Washington University School of Medicine in St. Louis
Michael Niehoff, Saint Louis University
Jinsong Zhang, Saint Louis University
John E. Morley, Saint Louis University
Erik S. Musiek, Washington University School of Medicine in St. Louis
Susan A. Farr, Saint Louis University
Thomas P. Burris, Washington University School of Medicine in St. Louis

Journal

PLoS ONE

Publication Date

2019

Volume

14

Issue

4

Inclusive Pages

e0215004

Document Type

Open Access Publication

DOI

10.1371/journal.pone.0215004

Rights and Permissions

Roby DA, Ruiz F, Kermath BA, Voorhees JR, Niehoff M, et al. (2019) Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease. PLOS ONE 14(4): e0215004. https://doi.org/10.1371/journal.pone.0215004

Recommended Citation

Roby, Deborah A.; Ruiz, Fernanda; Kermath, Bailey A.; Voorhees, Jaymie R.; Niehoff, Michael; Zhang, Jinsong; Morley, John E.; Musiek, Erik S.; Farr, Susan A.; and Burris, Thomas P., "Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease." PLoS ONE. 14, 4. e0215004. (2019).
https://digitalcommons.wustl.edu/open_access_pubs/7770