Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

Authors

Monique R. Heitmeier, Washington University School of Medicine in St. Louis
Richard C. Hresko, Washington University School of Medicine in St. Louis
Rachel L. Edwards, Washington University School of Medicine in St. Louis
Michael J. Prinsen, Washington University School of Medicine in St. Louis
Ma Xenia G. Ilagan, Washington University School of Medicine in St. Louis
Audrey R. Odom John, Washington University School of Medicine in St. Louis
Paul W. Hruz, Washington University School of Medicine in St. Louis

Journal

PLoS ONE

Publication Date

2019

Volume

14

Issue

5

Inclusive Pages

e0216457

Document Type

Open Access Publication

DOI

10.1371/journal.pone.0216457

Rights and Permissions

Heitmeier MR, Hresko RC, Edwards RL, Prinsen MJ, Ilagan MXG, et al. (2019) Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering. PLOS ONE 14(5): e0216457. https://doi.org/10.1371/journal.pone.0216457

Recommended Citation

Heitmeier, Monique R.; Hresko, Richard C.; Edwards, Rachel L.; Prinsen, Michael J.; Ilagan, Ma Xenia G.; John, Audrey R. Odom; and Hruz, Paul W., "Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering." PLoS ONE. 14, 5. e0216457. (2019).
https://digitalcommons.wustl.edu/open_access_pubs/7905