Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model

Authors

Yang Shi, Washington University School of Medicine in St. Louis
Melissa Manis, Washington University School of Medicine in St. Louis
Justin Long, Washington University School of Medicine in St. Louis
Kairuo Wang, Washington University School of Medicine in St. Louis
Patrick M. Sullivan, Duke University
Javier Remolina Serrano, Washington University School of Medicine in St. Louis
Rosa Hoyle, Washington University School of Medicine in St. Louis
David M. Holtzman, Washington University School of Medicine in St. Louis

Journal

Journal of Experimental Medicine

Publication Date

2019

Volume

216

Issue

11

First Page

2546

Last Page

2561

Document Type

Open Access Publication

DOI

10.1084/jem.20190980

Rights and Permissions

Shi Y, Manis M, Long J, Wang K, Sullivan PM, Remolina Serrano J, Hoyle R, Holtzman DM. Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model. J Exp Med. 2019 Nov 4;216(11):2546-2561. doi: 10.1084/jem.20190980. Epub 2019 Oct 10. © 2019 Shi et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

Recommended Citation

Shi, Yang; Manis, Melissa; Long, Justin; Wang, Kairuo; Sullivan, Patrick M.; Remolina Serrano, Javier; Hoyle, Rosa; and Holtzman, David M., "Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model." Journal of Experimental Medicine. 216, 11. 2546 - 2561. (2019).
https://digitalcommons.wustl.edu/open_access_pubs/8467