Journal
Elife
Publication Date
2-25-2020
Volume
9
First Page
e54208
Document Type
Open Access Publication
DOI
10.7554/eLife.54208
Rights and Permissions
Stoeber M, Jullié D, Li J, Chakraborty S, Majumdar S, Lambert NA, Manglik A, von Zastrow M. Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells. Elife. 2020 Feb 25;9. doi: 10.7554/eLife.54208. © 2020, Stoeber et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
Recommended Citation
Stoeber, Miriam; Jullié, Damien; Li, Joy; Chakraborty, Soumen; Majumdar, Susruta; Lambert, Nevin A.; Manglik, Aashish; and von Zastrow, Mark, "Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells." Elife. 9, e54208 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/8918
Concentration-dependent recruitment of mGsi and Nb33 probes to KOR in response to DynA, U69, and U50 (Figure 1I-K).
Figure 2—source data 1.csv (3 kB)
ET concentration-dependent recruitment of mGsi and Nb33 probes to KOR, or to KOR-TPD, or to KOR in the presence of Cmpd101.
Figure 3—source data 1.csv (2 kB)
Concentration-dependent recruitment of mGsi and Nb33 probes to MOR in response to DAMGO, ET, morphine, or PZM21.
Figure 5—source data 1.csv (1 kB)
Concentration-dependent recruitment of GRK2 to the plasma membrane in response to DynA or ET (Figure 5D).
Figure 6—source data 1.csv (1 kB)
Recruitment behavior of GRK2 to the plasma membrane in response to ET and DynA (Figure 5E–H).
Tranparent Reporting Form.docx (246 kB)
Recruitment of GRK2 to KOR clusters upon DynA or ET treatment (Figure 6D)
