Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy

Authors

Shuang Li, Washington University School of Medicine in St. Louis
Shixuan Liu, Washington University School of Medicine in St. Louis
Xiaoran Roger Liu, Washington University in St. Louis
Mengru Mira Zhang, Washington University in St. Louis
Weikai Li, Washington University School of Medicine in St. Louis

Journal

Blood Advances

Publication Date

2020

Volume

4

Issue

10

First Page

2202

Last Page

2212

Document Type

Open Access Publication

DOI

10.1182/bloodadvances.2020001750

Rights and Permissions

Shuang Li, Shixuan Liu, Xiaoran Roger Liu, Mengru Mira Zhang, Weikai Li; Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy. Blood Adv 2020; 4 (10): 2202–2212. doi: https://doi.org/10.1182/bloodadvances.2020001750

Recommended Citation

Li, Shuang; Liu, Shixuan; Liu, Xiaoran Roger; Zhang, Mengru Mira; and Li, Weikai, "Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy." Blood Advances. 4, 10. 2202 - 2212. (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9204