LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis

Authors

Manoj Arra, Washington University School of Medicine in St. Louis
Gaurav Swarnkar, Washington University School of Medicine in St. Louis
Ke Ke, Washington University School of Medicine in St. Louis
Jesse E. Otero, OrthoCarolina Hip and Knee Center
Jun Ying, Washington University School of Medicine in St. Louis
Xin Duan, Washington University School of Medicine in St. Louis
Takashi Maruyama, Akita University
Muhammad Farooq Rai, Washington University School of Medicine in St. Louis
Regis J. O'Keefe, Washington University School of Medicine in St. Louis
Gabriel Mbalaviele, Washington University School of Medicine in St. Louis
Jie Shen, Washington University School of Medicine in St. Louis
Yousef Abu-Amer, Washington University School of Medicine in St. Louis

Journal

Nature Communications

Publication Date

2020

Volume

11

Issue

1

First Page

3427

Document Type

Open Access Publication

DOI

10.1038/s41467-020-17242-0

Rights and Permissions

Arra, M., Swarnkar, G., Ke, K., Otero, J. E., Ying, J., Duan, X., . . . Abu-Amer, Y. (2020). LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis. Nature Communications, 11(1) doi:10.1038/s41467-020-17242-0 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Arra, Manoj; Swarnkar, Gaurav; Ke, Ke; Otero, Jesse E.; Ying, Jun; Duan, Xin; Maruyama, Takashi; Farooq Rai, Muhammad; O'Keefe, Regis J.; Mbalaviele, Gabriel; Shen, Jie; and Abu-Amer, Yousef, "LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis." Nature Communications. 11, 1. 3427 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9289