Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability

Authors

Sumeet Nayak, University of Massachusetts Medical School
Jennifer A Calvo, University of Massachusetts Medical School
Ke Cong, University of Massachusetts Medical School
Min Peng, University of Massachusetts Medical School
Emily Berthiaume, University of Massachusetts Medical School
Jessica Jackson, Washington University School of Medicine in St. Louis
Angela M Zaino, University of Connecticut - Storrs
Alessandro Vindigni, Washington University School of Medicine in St. Louis
M Kyle Hadden, University of Connecticut - Storrs
Sharon B Cantor, University of Massachusetts Medical School

Journal

Science Advances

Publication Date

2020

Volume

6

Issue

24

First Page

7808

Document Type

Open Access Publication

DOI

10.1126/sciadv.aaz7808

Rights and Permissions

Sumeet Nayak, et al. Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability. Science Advances 2020. 6(24):eaaz7808. DOI: 10.1126/sciadv.aaz7808. Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S.Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

Recommended Citation

Nayak, Sumeet; Calvo, Jennifer A; Cong, Ke; Peng, Min; Berthiaume, Emily; Jackson, Jessica; Zaino, Angela M; Vindigni, Alessandro; Hadden, M Kyle; and Cantor, Sharon B, "Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability." Science Advances. 6, 24. 7808 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9307