Journal
The Journal of Experimental Medicine
Publication Date
11-2-2020
Volume
217
Issue
11
First Page
e20200861
Document Type
Open Access Publication
DOI
10.1084/jem.20200861
Rights and Permissions
Barthélemy NR, Horie K, Sato C, Bateman RJ. Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease. J Exp Med. 2020;217(11):e20200861. doi:10.1084/jem.20200861.© 2020 Barthelemy et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
Recommended Citation
Barthélemy, Nicolas R.; Horie, Kanta; Sato, Chihiro; and Bateman, Randall J., "Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease." The Journal of Experimental Medicine. 217, 11. e20200861 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9405
shows replication in non-spiked plasma pool from healthy volunteers and method performance measured in the spike and recovery experiment.
jem_20200861_tables2.docx (27 kB)
shows peptides sequences and corresponding MS/MS transitions used for the quantitation of plasma tau peptides.
jem_20200861_tables3.docx (25 kB)
shows AUC comparison by DeLong test on p-tau217 and p-tau181 performance in separating amyloid positive from amyloid negative.
