Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

Authors

Keerthana Gnanapradeepan, The Wistar Institute
Julia I-Ju Leu, Perelman School of Medicine
Subhasree Basu, The Wistar Institute
Thibaut Barnoud, The Wistar Institute
Madeline Good, The Wistar Institute
Joyce V. Lee, Perelman School of Medicine
William J. Quinn, Perelman School of Medicine
Che-Pei Kung, Washington University School of Medicine in St. Louis
Rexford Ahima, Johns Hopkins University School of Medicine
Joseph A. Baur, Perelman School of Medicine
Kathryn E. Wellen, Perelman School of Medicine
Qin Liu, The Wistar Institute
Zachary T. Schug, The Wistar Institute
Donna L. George, Perelman School of Medicine
Maureen E. Murphy, The Wistar Institute

Journal

Elife

Publication Date

11-10-2020

Volume

9

First Page

e55994

Document Type

Open Access Publication

DOI

10.7554/eLife.55994

Rights and Permissions

eLife 2020;9:e55994 DOI: 10.7554/eLife.55994. © 2020, Gnanapradeepan et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

Recommended Citation

Gnanapradeepan, Keerthana; Leu, Julia I-Ju; Basu, Subhasree; Barnoud, Thibaut; Good, Madeline; Lee, Joyce V.; Quinn, William J.; Kung, Che-Pei; Ahima, Rexford; Baur, Joseph A.; Wellen, Kathryn E.; Liu, Qin; Schug, Zachary T.; George, Donna L.; and Murphy, Maureen E., "Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser." Elife. 9, e55994 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9830