Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

Authors

• Cinzia Federico, Washington University School of Medicine in St. Louis
• Kinan Alhallak, Washington University School of Medicine in St. Louis
• Jennifer Sun, Washington University School of Medicine in St. Louis
• Kathleen Duncan, Washington University School of Medicine in St. Louis
• Feda Azab, Washington University School of Medicine in St. Louis
• Gail P. Sudlow, Washington University School of Medicine in St. Louis
• Pilar de la Puente, Washington University School of Medicine in St. Louis
• Barbara Muz, Washington University School of Medicine in St. Louis
• Vaishali Kapoor, Washington University School of Medicine in St. Louis
• Luna Zhang, Washington University School of Medicine in St. Louis
• Fangzheng Yuan, Washington University School of Medicine in St. Louis
• Matea Markovic, Washington University School of Medicine in St. Louis
• Joseph Kotsybar, Washington University School of Medicine in St. Louis
• Katherine Wasden, Washington University School of Medicine in St. Louis
• Nicole Guenthner, Washington University School of Medicine in St. Louis
• Shannon Gurley, Washington University School of Medicine in St. Louis
• Justin King, Washington University School of Medicine in St. Louis
• Daniel Kohnen, Washington University School of Medicine in St. Louis
• Noha N. Salama, St. Louis College of Pharmacy
• Dinesh Thotala, Washington University School of Medicine in St. Louis
• Dennis E. Hallahan, Washington University School of Medicine in St. Louis
• Ravi Vij, Washington University School of Medicine in St. Louis
• John F. DiPersio, Washington University School of Medicine in St. Louis
• Samuel Achilefu, Washington University School of Medicine in St. Louis
• Abdel Kareem Azab, Washington University School of Medicine in St. Louis

Journal

Nature Communications

Publication Date

2020

Volume

11

Issue

1

First Page

6037

Document Type

Open Access Publication

DOI

10.1038/s41467-020-19932-1

Rights and Permissions

Federico C, Alhallak K, Sun J, Duncan K, Azab F, Sudlow GP, de la Puente P, Muz B, Kapoor V, Zhang L, Yuan F, Markovic M, Kotsybar J, Wasden K, Guenthner N, Gurley S, King J, Kohnen D, Salama NN, Thotala D, Hallahan DE, Vij R, DiPersio JF, Achilefu S, Azab AK. Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma. Nat Commun. 2020 Nov 27;11(1):6037. doi: 10.1038/s41467-020-19932-1 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Federico, Cinzia; Alhallak, Kinan; Sun, Jennifer; Duncan, Kathleen; Azab, Feda; Sudlow, Gail P.; de la Puente, Pilar; Muz, Barbara; Kapoor, Vaishali; Zhang, Luna; Yuan, Fangzheng; Markovic, Matea; Kotsybar, Joseph; Wasden, Katherine; Guenthner, Nicole; Gurley, Shannon; King, Justin; Kohnen, Daniel; Salama, Noha N.; Thotala, Dinesh; Hallahan, Dennis E.; Vij, Ravi; DiPersio, John F.; Achilefu, Samuel; and Azab, Abdel Kareem, "Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma." Nature Communications. 11, 1. 6037 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9844