Journal
Elife
Publication Date
11-18-2020
Volume
9
First Page
e59445
Document Type
Open Access Publication
DOI
10.7554/eLife.59445
Rights and Permissions
eLife 2020;9:e59445 DOI: 10.7554/eLife.59445. © 2020, Minn et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
Recommended Citation
Minn, Kyaw Thu; Fu, Yuheng C.; He, Shenghua; Dietmann, Sabine; George, Steven C.; Anastasio, Mark A.; Morris, Samantha A.; and Solnica-Krezel, Lilianna, "High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures." Elife. 9, e59445 (2020).
https://digitalcommons.wustl.edu/open_access_pubs/9944
Figures and figure supplements.pdf (21360 kB)
Dissociated and reseeded gastruloid cells show motility.mp4 (3874 kB)
Time-lapse confocal series from 3 to 27 hr after reseeding of dissociated gastruloid cells in 500 µm ECM microdiscs
Source data 1.xlsx (115 kB)
Metadata for gastruloid cells including cluster annotation, replicate number, and predicted mouse and monkey cell types and stages
Source data 2.xlsx (88 kB)
Differentially expressed genes of gastruloid clusters
Source data 3.xlsx (68 kB)
Shared highly variable genes (HVGs) between gastruloid and reference datasets used for average gene expression correlation, and correlation values
Source data 4.xlsx (56 kB)
Metadata for cyno monkey cells including monkey cell type and developmental stage, and predicted mouse cell type and developmental stage
Source data 5.xlsx (40 kB)
Metadata for reseed cells including cluster annotation, and prediction scores for gastruloid cell types
Source data 6.xlsx (84 kB)
Downregulated and upregulated genes, shared HVGs, and gene expression correlation values between reseed and gastruloids
Source data 7.xlsx (59 kB)
Predicted interactions between reseed clusters
Transparent reporting form.docx (66 kB)
Dissociated and reseeded gastruloid cells show motility.mp4 (3874 kB)
Time-lapse confocal series from 3 to 27 hr after reseeding of dissociated gastruloid cells in 500 µm ECM microdiscs
Source data 1.xlsx (115 kB)
Metadata for gastruloid cells including cluster annotation, replicate number, and predicted mouse and monkey cell types and stages
Source data 2.xlsx (88 kB)
Differentially expressed genes of gastruloid clusters
Source data 3.xlsx (68 kB)
Shared highly variable genes (HVGs) between gastruloid and reference datasets used for average gene expression correlation, and correlation values
Source data 4.xlsx (56 kB)
Metadata for cyno monkey cells including monkey cell type and developmental stage, and predicted mouse cell type and developmental stage
Source data 5.xlsx (40 kB)
Metadata for reseed cells including cluster annotation, and prediction scores for gastruloid cell types
Source data 6.xlsx (84 kB)
Downregulated and upregulated genes, shared HVGs, and gene expression correlation values between reseed and gastruloids
Source data 7.xlsx (59 kB)
Predicted interactions between reseed clusters
Transparent reporting form.docx (66 kB)
