Issue Date

2010

Abstract

Alpha-synuclein has been implicated in the cellular mechanisms that control auditory sensitivity. In other systems it can also confer protection against cellular injury. Auditory brainstem response thresholds and immunohistochemistry were used to assess the ability of alpha-synuclein to protect against oxidative damage to the cochlea.

Language

English

Publisher

Program in Audiology and Communication Sciences, Washington University School of Medicine

Subject (MeSH)

Alpha synuclein; Paraquat; Oxidative Stress; Cochlea

Document Type

Thesis

Advisor

Faddis, Brian T.

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