The C3-C3aR axis modulates trained immunity in alveolar macrophages

Authors

• Alexander P Earhart, Washington University School of Medicine in St. Louis
• Rafael Aponte Alburquerque, Washington University School of Medicine in St. Louis
• Marick Starick, Washington University School of Medicine in St. Louis
• Lorena Garnica, Washington University School of Medicine in St. Louis
• Ayse Naz Ozanturk, Washington University School of Medicine in St. Louis
• Rahul Kumar Maurya, Washington University School of Medicine in St. Louis
• Xiaobo Wu, Washington University School of Medicine in St. Louis
• Jeffrey Haspel, Washington University School of Medicine in St. Louis
• Hrishikesh S Kulkarni, Washington University School of Medicine in St. Louis
• et al.

Journal

Elife

Publication Date

9-10-2026

Volume

14

First Page

RP104977

Document Type

Open Access Publication

DOI

10.7554/eLife.104977

Rights and Permissions

Alexander P Earhart, Alberto E Lopez, Josue I Hernandez, Aasritha Nallapu, Deebly Chavez, Sayahi Suthakaran, Brian Yang, Jungheun Hyun, Rafael Aponte Alburquerque, Marick Starick, Lorena Garnica, Ayse Naz Ozanturk, Rahul Kumar Maurya, Xiaobo Wu, Jeffrey Haspel, Jae Woo Lee, Jaime Hook, Hrishikesh S Kulkarni (2026) The C3–C3aR axis modulates trained immunity in alveolar macrophages eLife 14:RP104977. https://doi.org/10.7554/eLife.104977.3. © 2025, Earhart, Lopez et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

Recommended Citation

Earhart, Alexander P; Aponte Alburquerque, Rafael; Starick, Marick; Garnica, Lorena; Ozanturk, Ayse Naz; Maurya, Rahul Kumar; Wu, Xiaobo; Haspel, Jeffrey; Kulkarni, Hrishikesh S; and et al., "The C3-C3aR axis modulates trained immunity in alveolar macrophages." Elife. 14, RP104977 (2026).
https://digitalcommons.wustl.edu/oa_4/7515

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.