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Submissions from 2022

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Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish, Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R McAdow, Brooke Burris, Deepika Dogra, Sven Reischauer, and Mayssa H Mokalled

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Lipidomics analysis of outer membrane vesicles and elucidation of the inositol phosphoceramide biosynthetic pathway in Bacteroides thetaiotaomicron, Mariana G Sartorio, Ezequiel Valguarnera, Fong-Fu Hsu, and Mario F Feldman

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The HERITAGE Family Study: A review of the effects of exercise training on cardiometabolic health, with insights into molecular transducers, Mark A Sarzynski, Treva K Rice, D C Rao, and et al

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Strategies to limit invasive fungal infection in a coronavirus disease 2019 (COVID-19) intensive care unit: The role of infection prevention for renovation and construction in resource-limited settings, Ornnicha Sathitakorn, Surachai Chaononghin, Panipak Katawethiwong, Thanus Pientong, David J. Weber, David K. Warren, Piyaporn Apisarnthanarak, and Anucha Apisarnthanarak

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A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model, Yurie Sato-Yamada, Amy Strickland, Yo Sasaki, Joseph Bloom, Aaron DiAntonio, and Jeffrey Milbrandt

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Genetic diversity fuels gene discovery for tobacco and alcohol use, Gretchen R B Saunders, Charles C Gu, John P Rice, Nancy L Saccone, Laura J Bierut, and et al.

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Comparative genomics of borderline oxacillin-resistant Staphylococcus aureus detected during a pseudo-outbreak of methicillin-resistant S. aureus in a neonatal intensive care unit, Sanjam S Sawhney, Eric M Ransom, Meghan A Wallace, Patrick J Reich, Gautam Dantas, and Carey-Ann D Burnham

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Morphologic design of nanostructures for enhanced antimicrobial activity, Fatma Al-Zahraa Sayed, Noura G Eissa, Yidan Shen, David A Hunstad, Karen L Wooley, and Mahmoud Elsabahy

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Low knowledge of HIV PrEP within a midwestern US cohort of persons who inject drugs, Sena Sayood, Laura R. Marks, Rupa Patel, Nathanial S. Nolan, Stephen Y. Liang, and Michael J. Durkin

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Non-targeted metabolomics of cooked cowpea (Vigna unguiculata) and pigeon pea (Cajanus cajan) from Ghana using two distinct and complementary analytical platforms, Brooke Sayre-Chavez, Bridget Baxter, Corey D Broeckling, María Muñoz-Amatriaín, Mark Manary, and Elizabeth P Ryan

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Episodic memories among irritable bowel syndrome (IBS) patients: An important aspect of the IBS symptom experience, Gregory S Sayuk, Carol S North, David E Pollio, Britt M Gott, and David H Alpers

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How risky are risk factors? An analysis of prenatal risk factors in patients participating in the congenital upper limb differences registry, Tyler Schaeffer, Maria F Canizares, Lindley B Wall, Deborah Bohn, Suzanne Steinman, Julie Samora, Mary Claire Manske, Douglas T Hutchinson, Apurva S Shah, Andrea S Bauer, and CoULD Study Group

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Characterization of the genomic and immunologic diversity of malignant brain tumors through multisector analysis, Maximilian O Schaettler, Megan M Richters, Anthony Z Wang, Zachary L Skidmore, Bryan Fisk, Albert H Kim, Michael R Chicoine, Joshua W Osbun, Eric C Leuthardt, Joshua L Dowling, Gregory J Zipfel, Ralph G Dacey, Hsiang-Chih Lu, Tanner M Johanns, Obi L Griffith, Malachi Griffith, Gavin P Dunn, and et al.

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A multitrait locus regulates sarbecovirus pathogenesis, Alexandra Schäfer, Emma S Winkler, Michael S Diamond, and et al

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Evaluation of noise regression techniques in resting-state fMRI studies using data of 434 older adults, Norman Scheel, Jeffrey N Keller, Ellen F Binder, Eric D Vidoni, Jeffrey M Burns, Binu P Thomas, Ann M Stowe, Linda S Hynan, Diana R Kerwin, Wanpen Vongpatanasin, Heidi Rossetti, C Munro Cullum, Rong Zhang, and David C Zhu

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Tumor lysis syndrome in a patient with metastatic endometrial cancer treated with lattice stereotactic body radiation therapy, Joshua P Schiff, Matthew B Spraker, Sai Duriseti, Sana Shaikh, Haris F Murad, David G Mutch, Clifford G Robinson, James Kavanaugh, and Alexander J Lin

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T Cell Subtype Profiling measures exhaustion and predicts anti-PD-1 response, Ian Schillebeeckx, Jon Earls, Kevin C Flanagan, Jeffrey Hiken, Alex Bode, Jon R Armstrong, David N Messina, Douglas Adkins, Jessica Ley, Ilaria Alborelli, Philip Jermann, and Jarret I Glasscock

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Associations of polymorphisms in the peroxisome proliferator-activated receptor gamma coactivator-1 alpha gene with subsequent coronary heart disease: An individual-level meta-analysis, Tessa Schillemans, Sharon Cresci, and et al

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Effect of race on prediction of brain amyloidosis by plasma Aβ42/Aβ40, phosphorylated tau, and neurofilament light, Suzanne E Schindler, Rachel L Henson, Yan Li, Benjamin Saef, Krista L Moulder, David Bradford, Anne M Fagan, Brian A Gordon, Tammie L S Benzinger, Joyce Balls-Berry, Randall J Bateman, Chengjie Xiong, John C Morris, and et al

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A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice, Erica G Schmitt, Kelsey A Toth, Samuel I Risma, Ana Kolicheski, Nermina Saucier, Rafael J. Feliciano Berríos, Zev J. Greenberg, Jennifer W. Leiding, Jack J. Bleesing, Akaluck Thatayatikom, Laura G. Schuettpelz, John R. Edwards, Tiphanie P. Vogel, and Megan A Cooper

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Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma, Nathalie Scholler, Armin Ghobadi, and et al

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A benzodiazepine activator locks K v 7.1 channels open by electro-mechanical uncoupling, Julian A Schreiber, Melina Möller, Mark Zaydman, Lu Zhao, Zachary Beller, Sebastian Becker, Nadine Ritter, Panpan Hou, Jingyi Shi, Jon Silva, Eva Wrobel, Nathalie Strutz-Seebohm, Niels Decher, Nicole Schmitt, Sven G Meuth, Martina Düfer, Bernhard Wünsch, Jianmin Cui, and Guiscard Seebohm

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External validation of the FEAR index in borderline acetabular dysplasia, Maria T Schwabe, John C Clohisy, Elizabeth A Graesser, Cecilia Pascual-Garrido, and Jeffrey J Nepple

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Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1, Madeline M Schwarz, David A Price, Safder S Ganaie, Annie Feng, Nawneet Mishra, Ryan M Hoehl, Farheen Fatma, Sarah H Stubbs, Sean P J Whelan, Xiaoxia Cui, Takeshi Egawa, Daisy W Leung, Gaya K Amarasinghe, and Amy L Hartman

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Implementation and early experience of a pediatric electrophysiology telehealth program, Jonathan Schweber, Lisa Roelle, Juliana Ocasio, Aarti S Dalal, Nathan Miller, George F Van Hare, and Jennifer N Avari Silva

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Mindfulness training for depressed older adults using smartphone technology: Protocol for a fully remote precision clinical trial, Abigail Schweiger, Thomas L Rodebaugh, Eric J Lenze, Katie Keenoy, Jason Hassenstab, Jeanne Kloeckner, Torie R Gettinger, and Ginger E Nicol

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Natural locus coeruleus dynamics during feeding, Natale R Sciolino, Alexxai V Kravitz, and Et al

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Identification of small regions of overlap from copy number variable regions in patients with hypospadias, Carter H Scott and Ina E Amarillo

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The role of neutrophil extracellular traps in acute lung injury, Davide Scozzi, Fuyi Liao, Alexander S Krupnick, Daniel Kreisel, and Andrew E Gelman

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Accuracy and reliability of diffusion imaging models, Nicole A. Seider, Babatunde Adeyemo, Ryland Miller, Dillan J. Newbold, Jacqueline M. Hampton, Kristen M. Scheidter, Jerrel Rutlin, Timothy O. Laumann, Jarod L. Roland, David F. Montez, Andrew N. Van, Annie Zheng, Scott Marek, Benjamin P. Kay, G. Larry Bretthorst, Yong Wang, Steven E. Petersen, Deanna M. Barch, Evan M. Gordon, Abraham Z. Snyder, Joshua S. Shimony, and Nico U. F. Dosenbach

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals, Margaret Sunitha Selvaraj, Lisa de Las Fuentes, Susan K. Dutcher, and et al.

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High-resolution imaging of protein secretion at the single-cell level using plasmon-enhanced FluoroDOT assay, Anushree Seth, Ekansh Mittal, Jingyi Luan, Samhitha Kolla, Monty B Mazer, Hemant Joshi, Rohit Gupta, Priya Rathi, Zheyu Wang, Jeremiah J Morrissey, Joel D Ernst, Cynthia Portal-Celhay, Sharon Celeste Morley, Jennifer A Philips, and Srikanth Singamaneni

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A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication, Ghjuvan'Ghjacumu Shackleford, Yo Sasaki, and et al.

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Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers, Ami N Shah, Ashwin Sunderraj, Brian Finkelman, Sharlene H See, Andrew A Davis, Lorenzo Gerratana, Firas Wehbe, Neelima Katam, Deva Mahalingam, William J Gradishar, Amir Behdad, Luis Blanco, and Massimo Cristofanilli

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Two-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an external historical control study, Bijal D Shah, Armin Ghobadi, and et al.

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Neutrophil-to-lymphocyte ratios in patients undergoing aortic valve replacement: The PARTNER trials and registries, Bahira Shahim, Alan Zajarias, and et al

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Severe ocrelizumab-induced enterocolitis treated successfully with ustekinumab, Janaki Shah, Ahmad Al-Taaee, Parakkal Deepak, and Anas Gremida

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Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: Updated results of the E1912 trial, Tait D Shanafelt, Amanda F Cashen, and et al.

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Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model, Riti Sharan, Allison N Bucsan, Shabaana A Khader, and et al

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Equity implications of hospital penalties during 4 years of the Comprehensive Care for Joint Replacement model, 2016 to 2019, Sukruth A Shashikumar, Andrew M Ryan, and Karen E Joynt Maddox

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Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia, Alaullah Sheikh, Brunda Tumala, Tim J Vickers, John C Martin, Bruce A Rosa, Subrata Sabui, Supratim Basu, Rita D Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D Head, Wandy Beatty, Hamid M Said, and James M Fleckenstein

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Dissemination and implementation science resources, training, and scientific activities provided through CTSA programs nationally: Opportunities to advance D&I research and training capacity, Rachel C Shelton, Rowena J Dolor, Jonathan Tobin, Ana Baumann, Catherine Rohweder, Sapana Patel, and Laura-Mae Baldwin

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Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA, Christian Shema Mugisha, Tung Dinh, Abhishek Kumar, Kasyap Tenneti, Jenna E Eschbach, Keanu Davis, Robert Gifford, Mamuka Kvaratskhelia, and Sebla B Kutluay

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The influence of green space on obesity in China: A systematic review, Jing Shen, Mengfei Li, Qianhui Wang, Ruidong Liu, Mengmeng Ji, and Ruopeng An

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TBX21 methylation as a potential regulator of immune suppression in CMS1 subtype colorectal cancer, Yuanyuan Shen, Yulia I Nussbaum, Yariswamy Manjunath, Justin J Hummel, Matthew A Ciorba, Wesley C Warren, Jussuf T Kaifi, Christos Papageorgiou, Rene Cortese, Chi-Ren Shyu, and Jonathan B Mitchem

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Bleeding and thrombotic complications associated with anticoagulation prior to lung transplantation: A case series, Hailey M. Shepherd, Ramsey R. Hachem, Chad A. Witt, Rodrigo V. Guillamet, Derek E. Byers, Benjamin D. Kozower, Bryan F. Meyers, Tsuyoshi Takahashi, G. Alexander Patterson, Varun Puri, Daniel Kreisel, and Ruben G. Nava

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CALGB 40603 (Alliance): Long-term outcomes and genomic correlates of response and survival after neoadjuvant chemotherapy with or without carboplatin and bevacizumab in triple-negative breast cancer, Jonathan H Shepherd, Cynthia Ma, and et al.

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Prefrontal cortex supports speech perception in listeners with cochlear implants, Arefeh Sherafati, Noel Dwyer, Aahana Bajracharya, Mahlega Samira Hassanpour, Adam T Eggebrecht, Jill B Firszt, Joseph P Culver, and Jonathan E Peelle

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Management of acute promyelocytic leukemia in the setting of acute COVID-19 infection, Kevin G Shim, Mallory Crain, Kristan Augustin, and Karolyn A Oetjen

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Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance, Mariko Shirane, Michael Paley, Wayne M Yokoyama, and et al.

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Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules, Yun Shi, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt, and et al.

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Durable melanoma control following disseminated talimogene laherparepvec herpetic infection, Leonid Shmuylovich, Aubriana M McEvoy, Ryan C Fields, Leonel Hernandez-Aya, George Ansstas, and David Y Chen

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An alternate technique for goniotomy: Description of procedure and preliminary results, Thomas Shute, Wesley Green, James Liu, and Arsham Sheybani

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Trends in matriculation from neurological surgery training programs into academic versus private practice, Neha Siddiqui, Vamsi P. Reddy, James L. Rogers, Donald K. E. Detchou, Imaima Casubhoy, Rhea Gopali, Subhang Bhalla, Mika Janbahan, Emily Morris, Meghna Priyanka Peesapati, and Nitin Agarwal

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Two cases of Wolfram syndrome who were initially diagnosed with type 1 diabetes, Francesca Silvestri, Valeria Tromba, Francesco Costantino, Nila Palaniappan, and Fumihiko Urano

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Implementation of an electronic, secure, web-based application to support routine hand hygiene observation with immediate direct feedback and anonymized benchmarking, Simon Simonet, Jonas Marschall, Rolf Kuhn, Matthias Schlegel, and Christian R Kahlert

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PARIS and SPARTA: Finding the Achilles' heel of SARS-CoV-2, Viviana Simon, Ali H Ellebedy, and et al

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Myeloid cell interferon responses correlate with clearance of SARS-CoV-2, Dhiraj K Singh, Ekaterina Aladyeva, Shibali Das, Bindu Singh, Ekaterina Esaulova, Amanda Swain, Mushtaq Ahmed, Journey Cole, Chivonne Moodley, Smriti Mehra, Larry S Schlesinger, Maxim N Artyomov, Shabaana A Khader, and Deepak Kaushal

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A unique high-output cardiac hypertrophy phenotype arising from low systemic vascular resistance in Cantu syndrome, Gautam K Singh, Conor McClenaghan, Manish Aggarwal, Hongjie Gu, Maria S Remedi, Dorothy K Grange, and Colin G Nichols

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Enhancing task fMRI preprocessing via individualized model-based filtering of intrinsic activity dynamics, Matthew F Singh, Anxu Wang, Michael Cole, ShiNung Ching, and Todd S Braver

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Adherence and engagement with a cognitive behavioral therapy-based conversational agent (Wysa for Chronic Pain) among adults with chronic pain: Survival analysis, Chaitali Sinha, Abby L Cheng, and Madhura Kadaba

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High temporal resolution measurements of movement reveal novel early-life physiological decline in C. elegans, Drew Benjamin Sinha and Zachary Scott Pincus

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Barriers and facilitators to diabetes screening and prevention after a pregnancy complicated by gestational diabetes, Drishti D. Sinha, Roxann C. Williams, Laura N. Hollar, Hannah R. Lucas, Bethany Johnson-Javois, Heidi B. Miller, Amanda Stoermer, Graham A. Colditz, Aimee S. James, and Cynthia J. Herrick

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Ethical, regulatory, and practical barriers to COVID-19 research: A stakeholder-informed inventory of concerns, Bryan A. Sisk, Kari Baldwin, Meredith Parsons, and James M. DuBois

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Factors affecting pathways to care for children and adolescents with complex vascular malformations: Parental perspectives, Bryan A Sisk, Anna Kerr, and Katherine A King

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers, Zachary L Skidmore, Jason Kunisaki, Yiing Lin, Kelsy C Cotto, Erica K Barnell, Jasreet Hundal, Kilannin Krysiak, Vincent Magrini, Lee Trani, Jason R Walker, Robert Fulton, Elizabeth M Brunt, Christopher A Miller, Richard K Wilson, Elaine R Mardis, Malachi Griffith, William Chapman, and Obi L Griffith

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M Smith, Angela M Verdoni, Haley J Abel, David Y Chen, Shamika Ketkar, Elizabeth R Leight, Christopher A Miller, and Timothy J Ley

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M. Smith, Angela M. Verdoni, Haley J. Abel, David Y. Chen, Shamika Ketkar, Elizabeth R. Leight, Christopher A. Miller, and Timothy J. Ley

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Opportunities to improve policy dissemination by tailoring communication materials to the research priorities of legislators, Natalie R Smith, Stephanie Mazzucca, Marissa G Hall, Kristen Hassmiller Lich, Ross C Brownson, and Leah Frerichs

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Validation of blood-based transcriptomic circadian phenotyping in older adults, S Kendall Smith, Peter Tran, Katherine A Madden, Jill Boyd, Rosemary Braun, Erik S Musiek, and Yo-El S Ju

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The Emotional Word-Emotional Face Stroop task in the ABCD study: Psychometric validation and associations with measures of cognition and psychopathology, Harry R Smolker, Kai Wang, Monica Luciana, James M Bjork, Raul Gonzalez, Deanna M Barch, Erin C McGlade, Roselinde H Kaiser, Naomi P Friedman, John K Hewitt, and Marie T Banich

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When REBOA grows wings: Resuscitative endovascular balloon occlusion of the aorta to facilitate aeromedical transport, Jason A Snyder, Douglas J E Schuerer, Grant V Bochicchio, and Mark H Hoofnagle

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Intracellular connections between basal bodies promote the coordinated behavior of motile cilia, Adam W J Soh, Louis G Woodhams, Anthony D Junker, Cassidy M Enloe, Benjamin E Noren, Adam Harned, Christopher J Westlake, Kedar Narayan, John S Oakey, Philip V Bayly, and Chad G Pearson

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JIB-04 has broad-spectrum antiviral activity and inhibits SARS-CoV-2 replication and coronavirus pathogenesis, Juhee Son, Shimeng Huang, Qiru Zeng, Traci L Bricker, James Brett Case, Ruochen Zang, Zhuoming Liu, Tamarand L Darling, Jian Xu, Houda H Harastani, Maria Florencia Gomez Castro, Hinissan P Kohio, Gaopeng Hou, Paul W Rothlauf, Adam L Bailey, Steven L Brody, Sean P J Whelan, Michael S Diamond, Adrianus C M Boon, Siyuan Ding, and et al

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Racial and ethnic minorities have a lower prevalence of airflow obstruction than non-Hispanic Whites, Akshay Sood, Hans Petersen, Congjian Liu, Orrin Myers, Xin Wang Shore, Bobbi A Gore, Rodrigo Vazquez-Guillamet, Linda S Cook, Paula Meek, and Yohannes Tesfaigzi

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Association of endocrine therapy initiation timeliness with adherence and continuation in low-income women with breast cancer, Nikita Sood, Ying Liu, Min Lian, Tracy Greever-Rice, Jill Lucht, Chester Schmaltz, and Graham A Colditz

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IL-1 reprogramming of adult neural stem cells limits neurocognitive recovery after viral encephalitis by maintaining a proinflammatory state, Allison L Soung, Veronica A Davé, Charise Garber, Eric D Tycksen, Lauren L Vollmer, and Robyn S Klein

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COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis, Allison L Soung, Abigail Vanderheiden, Xiaoping Jiang, Traci Bricker, Adrianus C M Boon, Robyn S Klein, and et al.

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22q11.2 Deletion Syndrome - A series of patients with midline skull base defects, Spencer S. Souza, Lia Jacobson, Dylan Chan, Anna Meyer, Jarod L. Roland, and Kimberly Luu

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De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines, Jasmin Sponagel, Siddhartha Devarakonda, Joshua B Rubin, Jingqin Luo, and Joseph E Ippolito

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Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment, Jasmin Sponagel, Jill K Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L Tinkum, Hannah Gass, Elena Nunez, Gary J Patti, Jingqin Luo, Joshua B Rubin, Joseph E Ippolito, and et al.

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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance, Dhivya Sridaran, Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat, Melissa Reimers, Eric H Kim, Manish K Thakur, Muhammad A Saeed, Russell K Pachynski, Markus A Seeliger, W Todd Miller, Felix Y Feng, and Nupam P Mahajan

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Advice to clinicians on communication from adolescents and young adults with cancer and parents of children with cancer, Meghana Srinivas, Erica C Kaye, Lindsay J Blazin, Justin N Baker, Jennifer W Mack, James M DuBois, and Bryan A Sisk

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Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site, Daniel Stadlbauer, Ali H Ellebedy, and et al.

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Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains, Max V Staller, Eddie Ramirez, Sanjana R Kotha, Alex S Holehouse, Rohit V Pappu, and Barak A Cohen

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Infantile-onset Pompe disease complicated by sickle cell anemia: Case report and management considerations, Rodrigo Tzovenos Starosta, Ying-Chen Claire Hou, Katelyn Leestma, Prapti Singh, Luke Viehl, Linda Manwaring, Jorge Luis Granadillo, Molly C Schroeder, Jamie N Colombo, Halana Whitehead, Patricia Irene Dickson, Monica L Hulbert, and Hoanh Thi Nguyen

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Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development, Neeltje Steeghs, Haeseong Park, and et al.

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Semaphorin-plexin signaling: From axonal guidance to a new X-linked intellectual disability syndrome, Jacqueline L Steele, Marwan S Shinawi, and et al.

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Implementing a new Emergency Department: A qualitative study of health professionals' change responses and perceptions, Nina Thórný Stefánsdóttir, Per Nilsen, Mette Bendtz Lindstroem, Ove Andersen, Byron J Powell, Tine Tjørnhøj-Thomsen, and Jeanette Wassar Kirk

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Left ventricular hypertrophy and biomarkers of cardiac damage and stress in aortic stenosis, Elliot J Stein, Nishath Quader, Alan Zajarias, Anna Vatterott, and et al

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Global variation in studies of articular cartilage procedures of the knee: A systematic review, R. Garrett Steinmetz, J. Jared Guth, Matthew J Matava, Matthew V Smith, and Robert H Brophy

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Ascertainment of vaccination status by self-report versus source documentation: Impact on measuring COVID-19 vaccine effectiveness, Meagan Stephenson, Jennie H Kwon, and et al

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A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study, Robert J Stephens, Erin M Evans, Michael J Pajor, Ryan D Pappal, Haley M Egan, Max Wei, Hunter Hayes, Jason A Morris, Nicholas Becker, Brian W Roberts, Marin H Kollef, Nicholas M Mohr, and Brian M Fuller

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Adverse events related to ultrasound-guided regional anesthesia performed by Emergency Physicians: Systematic review protocol, Sean P. Stickles, Deborah Shipley Kane, Chadd K. Kraus, Robert J. Strony, Enyo A. Ablordeppey, Michelle M. Doering, Daniel Theodoro, Jacques Simon Lee, and Christopher R. Carpenter

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Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa, Caroline Stienne, Richard Virgen-Slane, Lisa Elmén, Marisol Veny, Sarah Huang, Jennifer Nguyen, Elizabeth Chappell, Mary Olivia Balmert, Jr-Wen Shui, Michelle A Hurchla, Mitchell Kronenberg, Scott N Peterson, Kenneth M Murphy, Carl F Ware, and John R Šedý

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Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family, Peter J Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W D'Souza, Sanket Patel, Gautam Dantas, Gerard D Wright, and Alexei Savchenko