Submissions from 2023
A phase II study of palbociclib plus letrozole plus trastuzumab as neoadjuvant treatment for clinical stages II and III ER+ HER2+ breast cancer (PALTAN), Foluso O Ademuyiwa, Jingqin Luo, Yu Tao, Jeremy Hoog, Marie L Laury, Tracy Summa, Trish Hammerschmidt, Zhanfang Guo, Ashley Frith, Katherine Weilbaecher, Mateusz Opyrchal, Rebecca Aft, Katherine Clifton, Rama Suresh, Nusayba Bagegni, Ian S Hagemann, Michael D Iglesia, Cynthia X Ma, and et al.
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis, Kimberly A Dowd, Laura A VanBlargan, Rita E Chen, Bradley M Whitener, Jennifer Govero, Soila Sukupolvi-Petty, Michael S Diamond, and et al.
Sex-related differences in premature cardiovascular disease in familial hypercholesterolemia, Anandita Agarwala, Elena Deych, Laney K Jones, Amy C Sturm, Karen Aspry, Zahid Ahmad, Christie M Ballantyne, and Anne C Goldberg
Apical secretory glycoprotein complex contributes to cell attachment and entry by Cryptosporidium parvum, Marianna E. Akey, Rui Xu, Soumya Ravindran, Lisa Funkhouser-Jones, and L. David Sibley
Endogenous retrovirus RNA expression differences between race, stage and HPV status offer improved prognostication among women with cervical cancer, Jill Alldredge, Vinay Kumar, James Nguyen, Brooke E Sanders, Karina Gomez, Kay Jayachandran, Jin Zhang, Julie Schwarz, and Farah Rahmatpanah
Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors, Paweorn Angsutararux, Amal K Dutta, Martina Marras, Carlota Abella, Rebecca L Mellor, Jingyi Shi, Jeanne M Nerbonne, and Jonathan R Silva
Rapid profiling of DNA replication dynamics using mass spectrometry-based analysis of nascent DNA, Mohamed E Ashour, Andrea K Byrum, Alice Meroni, Jun Xia, Saurabh Singh, Roberto Galletto, Susan M Rosenberg, Alessandro Vindigni, and Nima Mosammaparast
Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA, Ishmael D. Aziati, Derek McFarland Jr., Avan Antia, Astha Joshi, Anahi Aviles-Gamboa, Preston Lee, Houda Harastani, David Wang, Solny A. Adalsteinsson, and Adrianus C M Boon
Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis, Derek A. G. Barisas, Ashraf Ul Kabir, Jun Wu, Karen Krchma, Minseo Kim, Madhav Subramanian, Bernd H. Zinselmeyer, Colin L. Stewart, and Kyunghee Choi
Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma, Erica K Barnell, Zachary L Skidmore, Kenneth F Newcomer, Monique Chavez, Katie M Campbell, Kelsy C Cotto, Nicholas C Spies, Marianna B Ruzinova, Tianjiao Wang, Brooj Abro, Bijal A Parikh, Eric J Duncavage, John L Frater, Yi-Shan Lee, Anjum Hassan, Justin A King, Daniel R Kohnen, Mark A Fiala, John S Welch, Geoffrey L Uy, Kiran Vij, Ravi Vij, Malachi Griffith, Obi L Griffith, Lukas D Wartman, and et al.
The history and organization of the Workshop on Population and Speciation Genomics, Julia M I Barth, Scott A Handley, Daniel Kintzl, Guy Leonard, Milan Malinsky, Michael Matschiner, Britta S Meyer, Walter Salzburger, Jan Stefka, and Emiliano Trucchi
Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort, Francesca L Beaudoin, Stacey L House, Deanna M Barch, and et al.
Allogeneic natural killer cell therapy, Melissa M Berrien-Elliott, Miriam T Jacobs, and Todd A Fehniger
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers, Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randall J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Jonathan Kipnis, Celeste M Karch, Oscar Harari, and et al.
Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity, Jennifer M Brazill, David Shin, Kristann Magee, Anurag Majumdar, Ivana R Shen, Valeria Cavalli, and Erica L Scheller
Phase Ib study of telisotuzumab vedotin in combination with erlotinib in patients with c-Met protein-expressing non-small-cell lung cancer, D Ross Camidge, Daniel Morgensztern, and et al.
Evaluation of birth by cesarean delivery and development of early-onset colorectal cancer, Yin Cao, Long H Nguyen, Stefani Tica, Ebunoluwa Otegbeye, Xiaoyu Zong, Bjorn Roelstraete, Andrew T Chan, Barbara B Warner, Olof Stephansson, and Jonas F Ludvigsson
The circular RNA landscape in multiple sclerosis: Disease-specific associated variants and exon methylation shape circular RNA expression profile, Giulia Cardamone, Elvezia Maria Paraboschi, Giulia Soldà, Giuseppe Liberatore, Valeria Rimoldi, Javier Cibella, Federica Airi, Veronica Tisato, Claudia Cantoni, Francesca Gallia, Donato Gemmati, Laura Piccio, Stefano Duga, Eduardo Nobile-Orazio, and Rosanna Asselta
Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma, Benedito A Carneiro, Saiama N Waqar, and et al.
Gut microbiota and microbiota-derived metabolites promotes endometriosis, Sangappa B Chadchan, Sumanta K Naik, Pooja Popli, Chandni Talwar, Satwikreddy Putluri, Chandrasekhar R Ambati, Michael A Lint, Andrew L Kau, Christina L Stallings, and Ramakrishna Kommagani
MRI-based classification of IDH mutation and 1p/19q codeletion status of gliomas using a 2.5D hybrid multi-task convolutional neural network, Satrajit Chakrabarty, Pamela LaMontagne, Joshua Shimony, Daniel S Marcus, and Aristeidis Sotiras
Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases, Michael Chan, Albert H Kim, Eric Leuthardt, and et al.
Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients, Pradeep S Chauhan, Alexander Shiang, Irfan Alahi, Wenjia Feng, Cayce Nawaf, Kevin Chen, Peter K Harris, Faridi Qaium, Casey Hatscher, Anna Antiporda, Lindsey Brunt, Lindsey R Mayer, Brian C Baumann, Eric H Kim, Melissa A Reimers, Zachary L Smith, Aadel A Chaudhuri, and et al.
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing, Fang Chen, Lisa de Las Fuentes, and et al.
Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma, Zhihong Chen, David H Gutmann, and et al.
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes, Mayank N K Choudhary, Kara Quaid, Xiaoyun Xing, Heather Schmidt, and Ting Wang
Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with Neurofibromatosis Type 1, Patrick J Cimino, Sonika Dahiya, and et al.
Synthetic biology design as a paradigm shift toward manufacturing affordable adeno-associated virus gene therapies, Logan Thrasher Collins, Selvarangan Ponnazhagan, and David T Curiel
Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer, Kelsy C Cotto, Yang-Yang Feng, Avinash Ramu, Megan Richters, Sharon L Freshour, Zachary L Skidmore, Huiming Xia, Joshua F McMichael, Jason Kunisaki, Katie M Campbell, Timothy Hung-Po Chen, Emily B Rozycki, Douglas Adkins, Siddhartha Devarakonda, Sumithra Sankararaman, Yiing Lin, William C Chapman, Christopher A Maher, Vivek Arora, Ramaswamy Govindan, Obi L Griffith, Malachi Griffith, and et al.
Motixafortide and G-CSF to mobilize hematopoietic stem cells for autologous transplantation in multiple myeloma: A randomized phase 3 trial, Zachary D Crees, Michael P Rettig, Reyka G Jayasinghe, Keith Stockerl-Goldstein, Feng Gao, Mark A Schroeder, Ravi Vij, John F DiPersio, and et al.
Venographic classification and long-term surgical treatment outcomes for axillary-subclavian vein thrombosis due to venous thoracic outlet syndrome (Paget-Schroetter syndrome), Esmaeel Reza Dadashzadeh, J. Westley Ohman, Pavan K. Kavali, Karen M. Henderson, Danita M. Goestenkors, and Robert W. Thompson
Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings, Matthew Dapas, Michelle A. Gill, and et al
Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: A multicenter, open-label, phase Ib/II trial, Macarena I de la Fuente, Brian A Van Tine, and et al.
Identification of bradycardia following remdesivir administration through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic Pharmacovigilance Project, Jason M Devgun, Rongmei Zhang, Jeffrey Brent, Paul Wax, Keith Burkhart, Alison Meyn, Sharan Campleman, Stephanie Abston, Kim Aldy, and Toxicology Investigators Consortium FACT Study Group
Prevalence of diarrheagenic Escherichia coli and impact on child health in Cap-Haitien, Haiti, Jenna N. Diaz, Lora L. Iannotti, Sherlie Jean Louis Dulience, Sydney Vie, Xuntian Jiang, Vadim Grigura, Jacques Boncy, Francesca J. Marhone Pierre, and F. Matthew Kuhlmann
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes, Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, and Farshid Guilak
Enhanced VWF clearance in low VWF pathogenesis: Limitations of the VWFpp/VWF:Ag ratio and clinical significance, Dearbhla Doherty, Michelle Lavin, Mary Byrne, Margaret Nolan, Jamie M O'Sullivan, Kevin Ryan, Niamh M O'Connell, Sandra L Haberichter, Pamela A Christopherson, Jorge Di Paola, Paula D James, and James S O'Donnell
Factor Xa cleaves SARS-CoV-2 spike protein to block viral entry and infection, Wenjuan Dong, Sean P J Whelan, and et al.
Final results from a phase 2b randomized, placebo-controlled clinical trial of RBX2660: A microbiota-based drug for the prevention of recurrent Clostridioides difficile infection, Erik R Dubberke, Robert Orenstein, Sahil Khanna, Beth Guthmueller, and Christine Lee
Staphylococcus aureus breast implant infection isolates display recalcitrance to antibiotic pocket irrigants, Jesus M. Duran Ramirez, Jana Gomez, Blake M. Hanson, Taha Isa, Terence M. Myckatyn, and Jennifer N. Walker
SVEP1 is an endogenous ligand for the orphan receptor PEAR1, Jared S Elenbaas, Upasana Pudupakkam, Katrina J Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C Lee, Kendall H Burks, Junedh M Amrute, Robert P Mecham, Carmen M Halabi, Arturo Aliso, Jorge Di Paola, and Nathan O Stitziel
Semantic wikis as flexible database interfaces for biomedical applications, Marco Falda, Manfredo Atzori, and Maurizio Corbetta
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway, Alexander D Fulford, Leonie Enderle, Jannette Rusch, Didier Hodzic, Maxine V Holder, Alex Earl, Robin Hyunseo Oh, Nicolas Tapon, and Helen McNeill
Cross-modal functional connectivity supports speech understanding in cochlear implant users, Amanda M Fullerton, Deborah A Vickers, Robert Luke, Addison N Billing, David McAlpine, Heivet Hernandez-Perez, Jonathan E Peelle, Jessica J M Monaghan, and Catherine M McMahon
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition, Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph S Clemen, Conrad C Weihl, John G Purdy, Steve P Gygi, and Malavika Raman
Sphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency, Ángel Gaudioso, Xuntian Jiang, Josefina Casas, Edward H Schuchman, and María Dolores Ledesma
Health utilities and quality-adjusted life years for patients with amyotrophic lateral sclerosis receiving reldesemtiv or placebo in FORTITUDE-ALS, Paulos Gebrehiwet, Lisa Meng, Stacy A Rudnicki, Phil Sarocco, Jenny Wei, Andrew A Wolff, Michael Butzner, Adriano Chiò, Jinsy A Andrews, Angela Genge, Dyfrig A Hughes, Carlayne E Jackson, Noah Lechtzin, Timothy M Miller, and Jeremy M Shefner
MiToS and King's staging as clinical outcome measures in ALS: A retrospective analysis of the FORTITUDE-ALS trial, Paulos Gebrehiwet, Lisa Meng, Stacy A Rudnicki, Phil Sarocco, Jenny Wei, Andrew A Wolff, Adriano Chiò, Jinsy A Andrews, Angela Genge, Carlayne E Jackson, Noah Lechtzin, Timothy M Miller, and Jeremy M Shefner
BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy, Yanyan Geng, Ping Li, Alice Butler, Bill Wang, Lawrence Salkoff, and Karl L Magleby
Nonalcoholic fatty liver disease is a risk factor for thiopurine hepatotoxicity in Crohn's disease, Alvin T George, Matthew Glover, Quazim Alayo, Maria Zulfiqar, Daniel R Ludwig, Matthew A Ciorba, Scott McHenry, and Parakkal Deepak
Factors associated with persistent postsurgical pain after total knee or hip joint replacement: A systematic review and meta-analysis, Arunangshu Ghoshal, Shivam Bhanvadia, Som Singh, Lauren Yaeger, and Simon Haroutounian
Virology under the microscope-A call for rational discourse, Felicia Goodrum, Carolina Lopez, Sean Whelan, and et al.
A somato-cognitive action network alternates with effector regions in motor cortex, Evan M Gordon, Roselyne J Chauvin, Andrew N Van, Aishwarya Rajesh, Ashley Nielsen, Dillan J Newbold, Nicole A Seider, Samuel R Krimmel, Kristen M Scheidter, Julia Monk, Ryland L Miller, Athanasia Metoki, David F Montez, Annie Zheng, Tomoyuki Nishino, Michael J Myers, Sydney Kaplan, Carolina Badke D'Andrea, Deanna M Barch, Christopher D Smyser, Cynthia E Rogers, Kelly N Botteron, John R Pruett, Jon T Willie, Peter Brunner, Joshua S Shimony, Benjamin P Kay, Scott Marek, Scott A Norris, Chad M Sylvester, Jarod L Roland, Steven E Petersen, Marcus E Raichle, Timothy O Laumann, Nico U F Dosenbach, and et al.
The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex-mediated quiescence, Zev J Greenberg, Luana Chiquetto Paracatu, Darlene A Monlish, Qian Dong, Michael Rettig, Nate Roundy, Rofaida Gaballa, Weikai Li, Wei Yang, Cliff J Luke, and Laura G Schuettpelz
Design of the COmbinatioN effect of FInerenone anD EmpaglifloziN in participants with chronic kidney disease and type 2 diabetes using a UACR Endpoint study (CONFIDENCE), Jennifer B Green, Amy K Mottl, George Bakris, Hiddo J L Heerspink, Johannes F E Mann, Janet B McGill, Masaomi Nangaku, Peter Rossing, Charlie Scott, Alain Gay, and Rajiv Agarwal
Corticosteroids increase the risk of invasive fungal infections more than tumor necrosis factor-alpha inhibitors in patients with inflammatory bowel disease, Martin H Gregory, Andrej Spec, Dustin Stwalley, Anas Gremida, Carlos Mejia-Chew, Katelin B Nickel, Matthew A Ciorba, Richard P Rood, Margaret A Olsen, and Parakkal Deepak
Appeal of tobacco quitline services among low-income smokers, Lauren M Grimes, Rachel Garg, Olivia Weng, Jennifer M Wolff, Amy McQueen, Kelly M Carpenter, and Matthew W Kreuter
KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer's disease-related pathology, John Grizzanti, William R. Moritz, Molly Stanley, Emily E. Caesar, Maria S. Remedi, Celeste M. Karch, Colin G. Nichols, David M. Holtzman, and et al.
Adipose-targeted SWELL1 deletion exacerbates obesity- and age-related nonalcoholic fatty liver disease, Susheel K. Gunasekar, John Heebink, Danielle H Carpenter, Ashutosh Kumar, Litao Xie, Haixia Zhang, Joel D. Schilling, and Rajan Sah
Oral low-dose naltrexone in the treatment of grontal fibrosing alopecia and lichen planopilaris: An uncontrolled open-label prospective study, Remi K. Hamel, Ling Chen, Cailin O'Connell, and Caroline Mann
Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs, Seong Kyu Han, Parker C Wilson, Benjamin D Humphreys, and et al.
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers, James J Harding, Haeseong Park, and et al.
Care of bullet-related injuries: A cross-sectional study of instructions and prescriptions provided on discharge from the emergency department, Jane M. Hayes, L J. Punch, and Kristen L. Mueller
Preclinical studies in Krabbe disease: A model for the investigation of novel combination therapies for lysosomal storage diseases, Gregory Heller, Allison M Bradbury, Mark S Sands, and Ernesto R Bongarzone
Structural and functional analysis of human pannexin 2 channel, Zhihui He, Yonghui Zhao, Michael J Rau, James A J Fitzpatrick, Rajan Sah, Hongzhen Hu, and Peng Yuan
The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes, Cassandra B Higgins, Joshua A Adams, Matthew H Ward, Zev J Greenberg, Małgorzata Milewska, Jiameng Sun, Yiming Zhang, Luana Chiquetto Paracatu, Qian Dong, Samuel Ballentine, Weikai Li, Ilona Wandzik, Laura G Schuettpelz, and Brian J DeBosch
Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: A phase 1 trial, David S Hong, Brian A Van Tine, Armin Ghobadi, Amanda Cashen, and et al.
Effect of a MUC5AC antibody (NPC-1C) administered with second-line gemcitabine and nab-paclitaxel on the survival of patients with advanced pancreatic ductal adenocarcinoma: A randomized clinical trial, Brandon M Huffman, Andrea Wang-Gillam, and et al.
A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain, Xueming Hu, Lixia Du, Shenbin Liu, Zhou Lan, Kaikai Zang, Jing Feng, Yonghui Zhao, Xingliang Yang, Zili Xie, Peter L. Wang, Aaron M. Ver Heul, Lvyi Chen, Vijay K. Samineni, Yan-Qing Wang, Kory J. Lavine, Robert W. Gereau, Gregory F. Wu, and Hongzhen Hu
A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration, Priscilla Y Hwang, Jairaj Mathur, Yanyang Cao, Jose Almeida, Jiayu Ye, Vasilios Morikis, Daphne Cornish, Maria Clarke, Sheila A Stewart, Amit Pathak, and Gregory D Longmore
The neurotoxin DSP-4 dysregulates the locus coeruleus-norepinephrine system and recapitulates molecular and behavioral aspects of prodromal neurodegenerative disease, Alexa F. Iannitelli, Michael A. Kelberman, Daniel J. Lustberg, Anu Korukonda, Katharine E. McCann, Bernard Mulvey, Arielle Segal, L Cameron Liles, Steven A. Sloan, Joseph D. Dougherty, and David Weinshenker
The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia, Ghayas C Issa, John DiPersio, Shalini Shenoy, and et al.
SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids, Yukitoshi Izumi, Angela M Reiersen, Eric J Lenze, Steven J Mennerick, and Charles F Zorumski
Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading, Nimansha Jain, Caroline A Lewis, Jason D Ulrich, and David M Holtzman
Docosahexaenoic acid stability in ready-to-use therapeutic food, Genevieve James, Kevin Stephenson, Meghan Callaghan-Gillespie, Mohamed Tabita Kamara, Hui Gyu Park, J Thomas Brenna, and Mark J Manary
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease, Shorena Janelidze, Nicolas R Barthélemy, Yingxin He, Randall J Bateman, and et al.
Necrotic cardiac myocytes skew macrophage polarization towards a classically activated phenotype, Wenlong Jiang, Luigi Adamo, Kenji Lim, Scot J Matkovich, Sarah Evans, Cibele Rocha-Resende, and Douglas L. Mann
Associations between cannabis use, polygenic liability for schizophrenia, and cannabis-related experiences in a sample of cannabis users, Emma C Johnson, Sarah M C Colbert, Paul W Jeffries, Rebecca Tillman, Nicole R Karcher, Elliot C Nelson, Arpana Agrawal, and et al.
mRNA vaccine mitigates SARS-CoV-2 infections and COVID-19, Christina M. Kackos, Sherri L. Surman, Bart G. Jones, Robert E. Sealy, Trushar Jeevan, Christopher J H Davitt, Sergei Pustylnikov, Tamarand L. Darling, Adrianus C M Boon, Julia L. Hurwitz, Marcelo M. Samsa, and Richard J. Webby
Dissecting cell identity via network inference and in silico gene perturbation, Kenji Kamimoto, Blerta Stringa, Christy M Hoffmann, Kunal Jindal, Lilianna Solnica-Krezel, and Samantha A Morris
Understanding misimplementation in U.S. state health departments: An agent-based model, Matt Kasman, Ross A Hammond, Rob Purcell, Louise Farah Saliba, Stephanie Mazzucca-Ragan, Margaret Padek, Peg Allen, Douglas A Luke, Sarah Moreland-Russell, Paul C Erwin, and Ross C Brownson
Navigating care for rare diseases: Caregiver and patient advice for families and clinicians managing care for vascular malformations, Anna M Kerr, Christine Bereitschaft, Kayla M Duty, and Bryan A Sisk
Potential uses of AI for perioperative nursing handoffs: A qualitative study, Christopher Ryan King, Ayanna Shambe, and Joanna Abraham
Complete remission of widely metastatic human epidermal growth factor receptor 2-amplified pancreatic adenocarcinoma after precision immune and targeted therapy with description of sequencing and organoid correlates, Daniel A King, S Peter Goedegebuure, Xiuli Zhang, Jasreet Hundal, Malachi Griffith, William E Gillanders, Haeseong Park, and et al.
Axatilimab for chronic graft-versus-host disease after failure of at least two prior systemic therapies: Results of a phase I/II study, Carrie L Kitko, Iskra Pusic, and et al.
Discovery and characterization of a new class of O-linking oligosaccharyltransferases from the Moraxellaceae family, Cory J Knoot, Paeton L Wantuch, Lloyd S Robinson, David A Rosen, Nichollas E Scott, and Christian M Harding
Provider beliefs in effectiveness and recommendations for primary HPV testing in 3 health-care systems, Gina R Kruse, Jacquelyn M Lykken, Eric J Kim, Jennifer S Haas, Robin T Higashi, Steven J Atlas, Anne Marie McCarthy, Jasmin A Tiro, Michelle I Silver, Celette S Skinner, and Aruna Kamineni
CIViCdb 2022: Evolution of an open-access cancer variant interpretation knowledgebase, Kilannin Krysiak, Arpad M Danos, Jason Saliba, Joshua F McMichael, Adam C Coffman, Susanna Kiwala, Erica K Barnell, Lana Sheta, Lynzey Kujan, Shahil Pema, Nicholas C Spies, Kaitlin A Clark, Ajay C Venigalla, Avila Suda, Benjamin J Ainscough, Haolin Shen, Alex R Marr, My H Hoang, Kartik Singhal, Mariam Khanfar, Brian V Li, Katie M Campbell, Kelsy C Cotto, Zachary L Skidmore, Jason R Walker, Malachi Griffith, Obi L Griffith, and et al.
Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases, Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, and Niraj H Tolia
Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation, Roxane Labrosse, Shalini Shenoy, and et al.
Higher dose oral fluconazole for the treatment of AIDS-related cryptococcal meningitis (HIFLAC)--Report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group, Umesh G. Lalloo, David B. Clifford, and et al.
Structural gray matter alterations in glioblastoma and high-grade glioma- A potential biomarker of survival, Bidhan Lamichhane, Patrick H Luckett, Donna Dierker, Ki Yun Park, Harold Burton, Michael Olufawo, Gabriel Trevino, John J Lee, Andy G S Daniel, Carl D Hacker, Daniel S Marcus, Joshua S Shimony, and Eric C Leuthardt
Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis-on-a-chip, Wyatt E. Lanik, Cliff J. Luke, Lila S. Nolan, Qingqing Gong, Lauren C. Frazer, Jamie M. Rimer, Sarah E. Gale, Raymond Luc, Shay S. Bidani, Carrie A. Sibbald, Angela N. Lewis, Belgacem Mihi, Pranjal Agrawal, Martin Goree, Marlie Maestas, Elise Hu, David F. Peters, and Misty Good
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles, Lindsey A. Lee, Samantha K. Barrick, Artur Meller, Jonathan Walklate, Jeffrey M. Lotthammer, Jian Wei Tay, W. Tom Stump, Gregory Bowman, Michael A. Geeves, Michael J. Greenberg, and Leslie A Leinwand
Air pollution and acute kidney injury in the U.S. Medicare population: A longitudinal cohort study, Whanhee Lee, Ziyad Al-Aly, and et al.
Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods, Miikael Lehtimäki, Binisha H Mishra, Coral Del-Val, Leo-Pekka Lyytikäinen, Mika Kähönen, C Robert Cloninger, Olli T Raitakari, Reijo Laaksonen, Igor Zwir, Terho Lehtimäki, and Pashupati P Mishra
GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program, Michael Lewis, Tao Cheng, Moe R Mahjoub, and et al.
Absolute and relative vaccine effectiveness of primary and booster series of COVID-19 vaccines (mRNA and adenovirus vector) against COVID-19 hospitalizations in the United States, December 2021-April 2022, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.
Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis, Joseph B Lin, Xiaolei Shen, Charles W Pfeifer, Fion Shiau, Andrea Santeford, Philip A Ruzycki, Brian S Clark, Qin Liu, Andrew J W Huang, and Rajendra S Apte
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness, Yize Li, Yige Wu, Rita Jiu-Hsien Lu, Siqi Chen, Yanyan Zhao, Wagma Caravan, Nataly Naser Al Deen, Matthew A Wyczalkowski, Michael C Wendl, Melissa A Reimers, Russell Pachynski, Brian A Van Tine, Feng Chen, Li Ding, and et al.
