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Submissions from 2026

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Whole-genome CRISPR screening identifies genetic modifiers of stem cell-derived islet transplantation, Marlie M Maestas, Kameron Bradley, Mira Shunkarova, Noyonika Mukherjee, Matthew Ishahak, James Lu, and Jeffrey R Millman

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Estimated effectiveness of 2024-2025 COVID-19 vaccination against severe COVID-19, Kevin C Ma, Jennie H Kwon, and et al.

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MDA5-MAVS and interferon-lambda signaling in the intestinal epithelium limit murine astrovirus infection, Heyde Makimaa, Harshad Ingle, Leran Wang, Somya Aggarwal, Hongju Deng, Elizabeth A Kennedy, Lynne Foster, Yuhao Li, and Megan T Baldridge

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Palbociclib with adjuvant endocrine therapy in early breast cancer: 5-year follow-up analysis of the global multicenter, open-label, randomized phase III PALLAS trial (ABCSG-42/AFT-05/PrE0109/BIG-14-13), E L Mayer, K Clifton, and et al.

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Patient-reported outcomes in the SERENA-6 trial of camizestrant plus CDK4/6 inhibitor in patients with advanced breast cancer and emergent ESR1 mutations during first-line endocrine-based therapy, E L Mayer, C Ma, and et al.

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Visual recognition of the anteroposterior female body axis drives spatial elements of male courtship in Drosophila, Ross M McKinney, Christian Monroy Hernandez, and Yehuda Ben-Shahar

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Sequential platinum and PARP Inhibition enhances PD1 immunotherapy efficacy in murine Brca2 mutated pancreatic cancer, John C McVey, Max M Wattenberg, Heather Coho, Kayjana Infante, Kelly Markowitz, Devora Delman, Cynthia Clendenin, Emma E Furth, Rashmi Tondon, Ben Z Stanger, Robert H Vonderheide, Kim A Reiss, and Gregory L Beatty

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SKIDA1 sustains MLL::ENL-expressing hematopoietic progenitors during neonatal stages and promotes B-lineage priming, Jonny Mendoza-Castrejon, Wei Yang, Elisabeth Denby, Rohini Muthukumar, Emily B Casey, Riddhi M Patel, Sarah K Tasian, and Jeffrey A Magee

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Phase I trial of ADP-A2AFP TCR T-cell therapy in patients with advanced hepatocellular or gastric hepatoid carcinoma, Tim Meyer, Benjamin R Tan, and et al.

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Costs and cost-effectiveness of a culturally adapted diabetes self-management and education program for Marshallese adults, Tzeyu L Michaud, Daniel Lamprecht-Carson, Su-Hsin Chang, Clare C Brown, Jennifer A Andersen, James P Selig, Philmar Mendoza Kabua, and Pearl McElfish

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Human chorionic gonadotropin decreases cerebral cystic encephalomalacia and parvalbumin interneuron degeneration in a pro-inflammatory model of mouse neonatal hypoxia-ischemia, Benjamin Miller, Alexander Crider, Bhooma Aravamuthan, and Rafael Galindo

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Regional brain age is decreased in children with sickle cell anemia, Amy E Mirro, Landon C Power, Jinli Wang, Paula Germino-Watnick, Heather Roberts, Yonca Cam, Kristin P Guilliams, Slim Fellah, Yasheng Chen, Hongyu An, Jin-Moo Lee, Andria L Ford, and Melanie E Fields

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Building capacity on hypertension management in Nigeria, Shivani Mishra, Daphne Lew, and et al.

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Matched unrelated vs haploidentical donor hematopoietic cell transplantation using posttransplant cyclophosphamide, Dipenkumar Modi, Ramzi Abboud, and et al.

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Ex vivo microfluidic model identifies a role for shear stress during ovarian tumor cell attachment to peritoneal mesothelial cells, Vasilios A Morikis, Breanna Baker, Jillian A Martin, Angela Schab, Alessandra DiMauro, Gregory D Longmore, and Whitney R Grither

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Exploring nurses' documentation prioritization strategies to alleviate EHR documentation burden: A phenomenological study, Rosemary Mugoya, Jennifer Thate, Fan Hao, Sarah C Rossetti, and Po-Yin Yen

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REV-ERB-alpha and -beta coordinately regulate astrocyte reactivity and proteostatic function, Collin J Nadarajah, Michelle Y Li, Elsa I Quillin, Kevin Boyer, Julie M Dimitry, Yining Chen, Melvin W King, Ibrahim O Saliu, Jiyeon Lee, Patrick W Sheehan, Albert A Davis, Mitchell A Lazar, Guoyan Zhao, and Erik S Musiek

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Excellent outcomes in feasibility study of radiation-free conditioning and transplant in pediatric severe aplastic anemia, Mithra Lakshmi Narasimhan, Irem Eldem, Jeffrey J Bednarski, Ginny L Schulz, Robert J Hayashi, and Shalini Shenoy

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Identification of distinct subtypes in immune tolerance after hematopoietic cell transplantation using the prospective ABLE1.0 pediatric study cohort, Bernard Ng, Shalini Shenoy, and et al.

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Clinical outcomes following mechanical thrombectomy in Pulmonary Embolism Response Team-consulted patients: A retrospective analysis, Ryan Nolan, Maanasi Samant, Suresh Vedantham, Westley Ohman, Nathan Droz, Kristen Sanfilippo, and Pavan Kavali

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Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants, Raymond Noordam, Karen Schwander, Lisa de Las Fuentes, Mary F Feitosa, Anh Do, C Charles Gu, Changwei Li, Michael A Province, Dabeeru C Rao, and et al.

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Risk factors for complication and reoperation in the treatment of discoid lateral meniscus in children and adolescents: A multicenter study, Suzanna Ohlsen, Jeffrey J Nepple, and et al.

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Exploring early antifungal activity of rezafungin as a stepping-stone for shorter treatment duration for candidemia: Pooled analysis of 2 randomized trials, Luis Ostrosky-Zeichner, Jalal A Aram, Mark Redell, George R Thompson, Oliver A Cornely, James A McKinnell, Andrej Spec, and Peter G Pappas

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SLC7A8 is essential for metabolic fitness and function of Th2 cells, Santosh K Panda, Do-Hyun Kim, Pritesh Desai, Shitong Wu, Patrick Fernandes Rodrigues, Raki Sudan, Yizhou Liu, Haerin Jung, Intelly Lee, Susan Gilfillan, Marina Cella, Steven J Van Dyken, and Marco Colonna

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Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics, David Papadopoli, Sergej Djuranovic, and et al.

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White matter hyperintensity burden and decline in driving performance among older adults, Madhur Parihar, Yasheng Chen, Byron Xu, Semere Bekena, Ramkrishna K Singh, Yiqi Zhu, Jean-Francois Trani, Jin-Moo Lee, David B Carr, Chia-Ling Phuah, Ganesh M Babulal, and Driving Real-World In-Vehicle Evaluation System (DRIVES) Project

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Single-cell multi-omic techniques highlight the diverse composition and intercellular interactions of the vestibular schwannoma tumor microenvironment, Shree S Pari, Sangami Pugazenthi, Albert H Kim, and Bhuvic Patel

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Phase 1 study of INBRX-105, a TNFRSF9 (4-1BB) and PD-L1 bispecific antibody, in patients with select solid tumors, Jong Chul Park, Doug R Adkins, and et al.

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Media reporting of the 2024 US Preventive Services Task Force mammography guideline update, Tamar Parmet, Yue Li, Joseph Cappella, Laura D Scherer, Erika A Waters, and Ashley J Housten

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Atypical superotemporal iris and retinal coloboma, Katina N Patterson, Margaret M Reynolds, and Gregg T Lueder

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What are the top 10 global research priorities for perianal Crohn's disease? The Global Perianal Crohn's Disease Priority Setting Partnership, Theo Pelly, Parakkal Deepak, and et al.

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Influence of obesity and insulin resistance with hepatic steatosis on the human plasma lipidome, Max C Petersen, Gordon I Smith, Aaron M Armando, Xiong Su, Oswald Quehenberger, Edward A Dennis, and Samuel Klein

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Costs of single maintenance and reliever therapy vs traditional therapy for asthma, Tri Pham, Abigail R Barker, Sarah A Eisenstein, Eliot Jost, Anna Volerman, Krutika Chauhan, Ross C Brownson, Timothy McBride, Mark D Huffman, Kaharu Sumino, Lynn B Gerald, Mario Castro, Anne E Dixon, and James G Krings

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Plasma ceramides levels in severe COVID-19 disease: Correlations with survival, Tri Pham, Andrea M Heredia Castillo, Andrew Atkinson, Linda R Peterson, and M Cristina Vazquez Guillamet

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Routine admission urinalysis has low clinical utility in psychiatric hospitalizations, Tri Pham, Devanshi Patel, Ana Berce, Alice Bewley, and Sena Sayood

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A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma, William C Pilcher, Lijun Yao, Yizhe Song, Kazuhito Sato, Julia T Wang, Reyka G Jayasinghe, Jennifer A Foltz, Mark A Fiala, Chiang I-Ling, Julie Fortier, Michael Slade, Stephen T Oh, Michael P Rettig, John F DiPersio, Shaji Kumar, Ravi Vij, Li Ding, and et al.

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Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations, Francisca Pinheiro, Ravi Kant, Saketh Chemuru, Nathalia Varejão, Adrián Velázquez-Campoy, David Reverter, Irantzu Pallarès, Michael L Gross, and Salvador Ventura

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The effects of ovine-derived reinforced tissue matrix surrounding silicone-based implants in a rat prepectoral reconstruction model, Sai L Pinni, Cameron Martin, Nicholas Fadell, Xiaochao Xia, Evan Marsh, Lauren Schellhardt, Xiaowei Li, Matthew D Wood, and Justin M Sacks

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Advancing peripheral nerve regeneration (Nerve SPACE 2025), Ken Porche, Tara Sara Saffari, Hollie Power, Wesley P Thayer, S Shelby Burks, John C Elfar, Alexander Y Shin, and David M Brogan

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Steroid hormone metabolites and mammographic breast density in premenopausal women, Ghazaleh Pourali, Kayode A Matthew, Myung Sik Jeon, Chongliang Luo, Gary J Patti, Jingqin Luo, and Adetunji T Toriola

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Economic evaluation of perioperative pembrolizumab plus standard of care as treatment for resectable locally advanced head and neck squamous cell carcinoma in the United States, Feng Qian, Arielle G Bensimon, Anjela Tzontcheva, Kimberly Benjamin, Ravindra Uppaluri, Douglas Adkins, Geoffrey Johnson, Catherine Fernan, Dandan Zheng, Yuexin Tang, Biruk Chafamo, and Dominic Muston

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Computational fluid dynamics-based risk stratification of modified Blalock-Taussig-Thomas shunt thrombogenicity, Yi Qiao, Ethan Penn, Jacob Miller, Scott Bugenhagen, Ram Rohatgi, Kelsey Mercer, Blaire Kulp, Jinli Wang, Pirooz Eghtesady, Guy M Genin, Edon J Rabinowitz, and David Bark

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Outcomes following matched sibling donor transplantation for severe combined immunodeficiency: A report from the PIDTC, Ahmad Rayes, Jeffrey J Bednarski, and et al.

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Cell type-specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease, Yunxiao Ren, Ming Hu, Yang E Li, Andrew A Pieper, Jeffrey Cummings, and Feixiong Cheng

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Effects of dual-eligible Integrated Care Plans on Medicaid enrollment and retention: Evidence from the Implementation of Medicare-Medicaid Plans, Eric T Roberts, Eliza Macneal, Kenton J Johnston, and José F Figueroa

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4-Aminoquinolines block heme iron reactivity and interfere with artemisinin action, Melissa Rosenthal and Daniel E Goldberg

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Identifying disparities in same-day surgery cancellations: Impact of race and socioeconomic factors in a pediatric health system, Nicole M Santucci, Daniel Alligood, Amanda Maytin-Hevia, Danyi Wang, Kelly Chilson, Jesse Vrecenak, Andrew Yeh, and Colin A Martin

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PIEZO mechanosensitivity in chondrocytes is differentially modulated by L-type and T-type voltage-sensitive ion channels, Alireza Savadipour, Gabrielle K Marushack, Robert J Nims, Jaquelin M Garcia-Castorena, Wolfgang Liedtke, and Farshid Guilak

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Intercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones, William C Schmidt, Henry L Schreiber, Rachael E S Hammann, Chloe L P Obernuefemann, Karla Bergeron, Aleksandra Klim, Daniel Wong, Kefu Du, Scott J Hultgren, and et al.

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Infant sensory gating and a developmental cascade to autistic traits and anxiety, Rebecca F Schwarzlose

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Early neurodevelopmental outcomes in children with congenital heart disease, Mike Seed, Cynthia Ortinau, Caroline Lee, and et al.

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Efficient multi-kilobase knock-ins in mice and cell lines using CRISPR/Cas9 and rAAV donors with unbiased whole-genome characterization by LOCK-seq, Monica F Sentmanat, Zi Teng Wang, Evguenia Kouranova, Samuel T Peters, Wan Ching Chan, Jed Lin, Yong Miao, J Michael White, Mia Wallace, and Xiaoxia Cui

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Cutibacterium adaptation to life on humans provides a potential C acnes infection biomarker, Md Shafiuddin, Wen-Chi Huang, Gabriel William Prather, Jeffrey Ryan Anton, Andrew Lawrence Martin, Sydney Brianna Sillart, Jonathan Z Tang, Michael R Vittori, Michael J Prinsen, Jessica Jane Ninneman, Chandrashekhara Manithody, Jeffrey P Henderson, Alexander W Aleem, Ma Xenia Garcia Ilagan, and William H McCoy 4th

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Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment, Irina Shchukina, Carlos J Rodriguez-Hernandez, Heather S Ruiz, Maksim Kleverov, Rachel L Mintz, Katsutaka Mineura, Subhadra C Gunawardana, Sunnie Hsiung, Bishan Bhattarai, Veronika Vachova, Jan Kossl, Denis A Mogilenko, Rachael L Field, Tran H Nguyen, Quazim A Alayo, Christopher G Huckstep, Barbora Vander Wielen, Jonathan R Brestoff, Sheila A Stewart, David W Piston, Takeshi Egawa, Daniel Kreisel, Gwendalyn J Randolph, and Maxim N Artyomov

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A chemogenetic approach for temporal and cell-specific activation of endogenous GPCRs in vivo, Gwendolyn Shingles, Qianqian Pang, Jian Weng, Ryan Singer, Waleed Babar, Jiaqi Shen, Luis Vazquez-Rivera, Yao Chen, Peng Li, and Wenjing Wang

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Accurate chromatin marks peak calling with Omnipeak, Oleg Shpynov and Maxim N Artyomov

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Knowledge, interest, and willingness of hematologists and oncologists to care for adults with vascular anomalies, Bryan A Sisk, Anna M Kerr, Sally Cohen-Cutler, Margaret T Lee, Katie Harmoney, Alexandra Borst, Shelley E Crary, Shelbie Fishman, Stephanie Chen, Danielle Cicka, Stephanie Milam, Christine Bereitschaft, and Kristen M Sanfilippo

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Abnormalities in sensorimotor brain function are related to chronicity of low back pain, Jo Armour Smith, Rongwen Tain, Kelli G Sharp, Laura M Glynn, Linda R Van Dillen, Jesse V Jacobs, and Steven C Cramer

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An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival, Kyle S Smith, Jeff M Michalski, and et al.

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Amyloidosis of bridging veins is a pathologic feature of Alzheimer's disease, Leon C D Smyth, Daan Verhaege, Elio Standen-Bloom, Yue Wu, Steffen E Storck, Pavle Boskovic, Benjamin A Plog, Tornike Mamuladze, Jose A Mazzitelli, Zhuoying Wang, Daniel D Lee, Gwendalyn J Randolph, Katherine E Schwetye, Song Hu, Jonathan Kipnis, and et al.

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Cumulative lifespan stress, inflammation, and racial disparities in mortality between Black and White adults, Isaiah D Spears, Aaron J Gorelik, Sara A Norton, Michael J Boudreaux, Megan W Wolk, Jayne Siudzinski, Sarah E Paul, Mary A Cox, Cynthia E Rogers, Thomas F Oltmanns, Patrick L Hill, and Ryan Bogdan

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A microenvironment-driven HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes, Neetu Srivastava, Anthony N Vomund, Rongzhen Yu, Orion J Peterson, Yuqing Yang, David P Turicek, Omar Abousaway, Tiandao Li, Pamela Stone, Aisha Ansar, Rima Melhem, Bo Zhang, Chang Liu, Hao Hu, Chyi-Song Hsieh, Laura Campisi, Emil R Unanue, Ana Maria Arbelaez, Cheryl F Lichti, Xiaoxiao Wan, and et al.

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Recognizing structural and social determinants of health in the diagnosis and care of dementia, Shana D Stites, Sharnita Midgett, Nisha Patel, Kimberly Halberstadter, Rosalie Schumann, Marissa L Streitz, Yidan Shi, John C Morris, Jason Flatt, Crystal M Glover, and Dawn Mechanic-Hamilton

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Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice, G Travis Tabor, Alexandra Litvinchuk, Yun Chen, Austin Allison, Carisa Zeng, Hao Hu, Peter B Lin, Prabal Sharma, Samira Parhizkar, Sihui Song, Xin Bao, Abhirami K Iyer, Shih Feng You, Javier Remolina Serrano, Melissa Manis, Emily Franke, Anil G Cashikar, Carla M Yuede, Celeste M Karch, Eric J Huang, Maxim Artyomov, Jason D Ulrich, David M Holtzman, and et al.

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Ultrasound applications in the treatment of major depressive disorder: A systematic review of techniques and therapeutic potentials in clinical trials and animal model studies, Gansheng Tan, Hong Chen, and Eric C Leuthardt

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Multi-center comparison of corticotropin releasing hormone vs. desmopressin stimulation responses in inferior petrosal sinus sampling for Cushing's disease, Samuel A Tenhoeve, Julie M Silverstein, Albert H Kim, and et al.

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Perceived HIV risk, barriers, and preferences for HIV testing in structurally vulnerable communities in St. Louis: A Best-Worst scaling survey, Emmanuel K Tetteh, Noelle Le Tourneau, Gregory Gross, McKenzie Swan, Tyrell Manning, Justin Cole, Katie Wolf, Lawrence Hudson-Lewis, Julia D López, Todd Combs, and Virginia R McKay

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Modeling clinical relevance and risk in yttrium-90 radioembolization of the liver: Lung shunt fraction variability according to imaging modality, cancer type, and tumor size, M Allan Thomas, Tharun Alamuri, Ryan C Lee, Dan Giardina, John Karageorgiou, Naganathan Mani, Daniel A Braga, and Christopher D Malone

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The win ratio for evaluating edoxaban vs dalteparin for cancer-associated venous thromboembolism: An analysis of the randomized Hokusai Venous Thromboembolism Cancer trial, Nick van Es, Luuk J J Scheres, Kristen M Sanfilippo, Harry Büller, Marc Carrier, Marcello Di Nisio, Michael Grosso, Renato D Lopes, William F McIntyre, Bjorn Redfors, Annelise Segers, Peter Verhamme, Jeffrey I Weitz, Patrick M Bossuyt, and Deborah M Siegal

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A multicomponent strategy to increase human papillomavirus vaccination rates in primary care: A cluster randomized clinical trial, Ruoyun Wang, Lei Liu, Sherry Dodd, Sharon Graham, Shannon Rook, Lauren Ericson, Katie Plax, Abigail Barker, Virginia McKay, Michelle I Silver, Jason G Newland, and Allison A King

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Lipocalin 2 orchestrates resistance to ferroptosis via AXL, Sabrina Z Wang, J Payton Timken, Ellen S Hong, Sehaj Kaur, Eli Newby, Kristen E Kay, Erin E Mulkearns-Hubert, Daniel J Silver, Juyeun Lee, Joshua B Rubin, James R Connor, Loic P Deleyrolle, Deanna Tiek, Andrew Dhawan, and Justin D Lathia

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Smoldering multiple myeloma in the United States: A population-based analysis, Shi-Yi Wang, Rong Wang, Martin Schoen, John H Huber, Eric J Feuer, Jennifer Ruhl, Natalia Neparidze, Xiaomei Ma, Amy J Davidoff, and Su-Hsin Chang

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Emerging options and future strategies in immunotherapy for advanced lung squamous-cell carcinoma, Y Wang, R Rosell, F R Hirsch, S Lu, R Govindan, K Park, S Peters, and J J Zhang

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Differential virulence and immune recognition of Klebsiella pneumoniae O-antigen subtypes O2α and O2β, Paeton L Wantuch, Lloyd S Robinson, Cory J Knoot, Christian M Harding, and David A Rosen

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Divergent humoral immune signatures in response to Klebsiella pneumoniae bacteremia, Paeton L Wantuch, Nadia Wattad, and David A Rosen

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Diverse misfolding mutant digestive enzymes cause chronic pancreatitis through common pathways, Steven J Wilhelm, Grace E Curry, Neel Matiwala, Jianguo Lin, Tran Quach, Mark E Lowe, Miklós Sahin-Tóth, and Xunjun K Xiao

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Intersecting challenges: Substance use and mental health disparities across self-reported disability status, Jessica Williams, Xiao Li, Hannah S Szlyk, Erin Kasson, Nathaniel A Dell, Alex Ramsey, and Patricia A Cavazos-Rehg

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Clostridioides difficile colonization and infection in pediatric oncology and stem cell transplant patients, Daniel N Willis, Erik R Dubberke, Robert J Hayashi, Phillip I Tarr, David B Haslam, Tiffany Hink, Jingqin Luo, Yu Tao, Amruta Padhye, Erin M Hall, and Gregory A Storch

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Performance of multiple multi-cancer detection tests using a large independent reference set (Alliance A212102), Marie E Wood, Mark Watson, and et al.

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Clinical performance of a novel point-of-care high-sensitivity cardiac troponin I assay, Alan H B Wu, Stacey L House, and et al.

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Variable and conserved features of copy-back viral genome populations generated de novo during Sendai virus infection, Yanling Yang, Yuchen Wang, and Carolina B López

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Mitochondrial presequences harbor variable strengths to maintain organellar function, Youmian Yan, Baigalmaa Erdenepurev, Thiago N Menezes, Ian Collinson, and Natalie M Niemi

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Leveraging patient data to detect systematic shifts in daptomycin susceptibility testing associated with reduced prescribing, Mark A Zaydman, Laurel Glaser, Daniel S Herman, Mason Kressloff, Vahid Azimi, Christine R Lockowitz, and Rebekah E Dumm

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Foot-specific exercise intervention for forefoot deformity in individuals with type 2 diabetes and peripheral neuropathy: A randomized controlled clinical trial with 3-year follow-up, J A Zellers, K Steger-May, P K Commean, H-J Jeong, E M Bullard, M J Mueller, and M K Hastings

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Atomic models of the Toxoplasma cell invasion machinery, Jianwei Zeng, Yong Fu, Pengge Qian, Wei Huang, Qingwei Niu, Wandy L Beatty, Alan Brown, L David Sibley, and Rui Zhang

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A catecholamine-independent pathway controlling adaptive adipocyte lipolysis, Xiao Zhang, Sreejith S Panicker, Jordan M Bollinger, Anurag Majumdar, Rami Kheireddine, Lila F Dabill, Clara Kim, Brian Kleiboeker, Fengrui Zhang, Kristann L Magee, Adam Kepecs, Gretchen A Meyer, Irfan J Lodhi, Erica L Scheller, and et al.

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Automating evaluation of LLM-generated responses to patient questions about rare diseases, Min Zhao, Inez Y Oh, Aditi Gupta, Sally Cohen-Cutler, Kathryn M Harmoney, Albert M Lai, and Bryan A Sisk

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Epithelial-mesenchymal transition and stress adaptations underlie yttrium-90 resistance in liver cancer cell lines, Alexander Zheleznyak, Dhanusha Duraiyan, Prasanth Thunuguntla, Jessica Camacho, Shuang Wu, Jingxia Liu, Jason D Weber, Daniel L J Thorek, Benjamin S Strnad, Ryan C Fields, Matthew A Ciorba, Christine Yoon, Valerie Blanc, Nicholas Davidson, Jessica Silva-Fisher, and Christopher D Malone

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Comparison of variant callers using 60 532 multi-ancestry whole genome sequences, Hufeng Zhou, Nathan O Stitziel, and et al.

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β2 and β3a regulatory subunits can coassemble in the same BK channels, Yu Zhou, Vivian Gonzalez-Perez, Xiao-Ming Xia, Gopal S Kallure, Sandipan Chowdhury, and Christopher J Lingle

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Lost before forgetting: Objective driving metrics track navigation deficits tied to preclinical Alzheimer's disease, Yiqi Zhu, Ramkrishna K Singh, Semere Bekena, David C Brown, Chen Chen, Matthew Blake, Jean-François Trani, and Ganesh M Babulal

Submissions from 2025

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LRRC8 channel complexes counterbalance KATP channels to mediate swell-secretion coupling in mouse pancreatic β cells, Tarek Mohamed Abd El-Aziz, Chen Kang, Litao Xie, John D. Tranter, Sumit Patel, Rahul Chadda, Maria S. Remedi, and Rajan Sah

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Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: A prespecified analysis of the DARE-19 randomized trial, Mohammad Abdel Jawad, Ali Javaheri, and et al.

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Autophagy is required for the therapeutic effects of the NAD+ precursor nicotinamide in obesity-related heart failure with preserved ejection fraction, Mahmoud Abdellatif, Moydul Islam, Abhinav Diwan, and et al.

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Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries, Javier Abello, Ying Yin, Yonghui Zhao, Josh Maurer, Jihui Lee, Cherokee Bodell, Jahmiera Richee, Zarek Burton, Megan E Goeckel, Michelle Lin, Carmen M Halabi, Rajan Sah, Amber N Stratman, and et al.

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Low frequency, high complexity: Assessing skill decay in transesophageal echocardiography post-simulation training, Enyo Ablordeppey, Emily Terian, Collyn T Murray, Laura Wallace, Wendy Huang, Erica Blustein, Alexander Croft, Ernesto Romo, Mansi Agarwal, and Daniel Theodoro

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Patient-centered televisit for chronic obstructive pulmonary disease discharge transitions: User-centered design study, Joanna Abraham, Alicia Meng, Nicolas Caravelli, Leah Traeger, May Nguyen, Vineet Arora, and Valerie G Press

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GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau, Diana Acosta Ingram, Jacob Marsh, Celeste M Karch, and et al.

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Do risk factors for HCC impact the association of CT/MRI LIRADS major features with HCC? An individual participant data meta-analysis, Robert G Adamo, Daniel R Ludwig, Tyler J Fraum, and et al.

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Baseline clinical characterization of participants in the Accelerating Medicines Partnership Schizophrenia program, Jean Addington, Daniel Mamah, and et al.