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Submissions from 2025

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Identification of a seasonal influenza vaccine-induced broadly protective neuraminidase antibody, Anders Madsen, Nisreen M A Okba, Tossapol Pholcharee, Hanover C Matz, Huibin Lv, Maria Ibanez Trullen, Julian Q Zhou, Jackson S Turner, Aaron J Schmitz, Fangjie Han, Stephen C Horvath, Sameer Kumar Malladi, Florian Krammer, Nicholas C Wu, and Ali H Ellebedy

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Robust photogrammetric scalp morphology estimation for functional optical neuroimaging, Abigail L Magee, Calamity Svoboda, Tessa G George, Alvin A Agato, Edward J Richter, Joseph P Culver, and Adam T Eggebrecht

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MU-Glioma Post: A comprehensive dataset of automated MR multi-sequence segmentation and clinical features, Esmat Mahmoud, Jaime Gass, Yaseen Dhemesh, Josh Greaser, Karolina Pogorzelski, Edvin Isufi, Filip Garrett, Jonathan Thacker, Nourel Hoda Tahon, Jason Sinclair, Lester Layfield, Talissa Altes, and Ayman Nada

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Poor sleep is common in treatment-resistant late-life depression and associated with poorer antidepressant response: Findings from the OPTIMUM clinical trial, Michael S B Mak, Marie Anne Gebara, Eric J Lenze, Daniel M Blumberger, Patrick J Brown, Pilar Cristancho, Alastair J Flint, Jordan F Karp, Helen Lavretsky, J Philip Miller, Charles F Reynolds 3rd, Steven P Roose, Benoit H Mulsant, and Sarah T Stahl

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Combining radioembolization and immune checkpoint inhibitors for the treatment of hepatocellular carcinoma: The quest for synergy, Christopher D Malone, Suryansh Bajaj, Aiwu He, Kabir Mody, Ryan M Hickey, Ammar Sarwar, Sunil Krishnan, Tushar C Patel, and Beau B Toskich

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Digital gait biomarkers in Parkinson's disease: Susceptibility/risk, progression, response to exercise, and prognosis, Martina Mancini, Gammon M Earhart, and et al.

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Comparative outcomes following Candida bloodstream infection in patients with left ventricular assist devices, Armaghan-E-Rehman Mansoor, Gayathri Krishnan, Julio C Zuniga-Moya, Benjamin Papadopoulus, Andrej Spec, and Ige George

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Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions, Suifang Mao, Michael J Holtzman, and et al.

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The promise and peril of comparing fluorescence lifetime in biology revealed by simulations, Pingchuan Ma, Peter Chen, Scott Sternson, and Yao Chen

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Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier, Lingaiah Maram, Jessica M Michael, Henry Politte, Vaishnavi S Srirama, Aymen Hadji, Mohammad Habibi, Meredith O Kelly, Rita T Brookheart, Brian N Finck, Lamees Hegazy, Kyle S McCommis, and Bahaa Elgendy

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Iodine-promoted oxidative cross-coupling for the synthesis of (E)-2-(3-oxo-3-phenylprop-1-en-1-yl)-3-phenylquinazolin-4(3 H)-one via C-H activation: Development of synthetic TLX agonists, Lingaiah Maram, Puhan Zhao, Thomas Koelblen, Lamees Hegazy, Thomas P Burris, and Bahaa Elgendy

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Impact of transcatheter aortic valve replacement use ratio on outcomes in patients with aortic valve disease, Theodore Marghitu, Sophia H Roberts, June He, Nicholas Kouchoukos, Puja Kachroo, Harold Roberts, Ralph Damiano, Alan Zajarias, Marc Sintek, John Lasala, Alexander A Brescia, and Tsuyoshi Kaneko

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Ultra high density imaging arrays in diffuse optical tomography for human brain mapping improve image quality and decoding performance, Zachary E Markow, Jason W Trobaugh, Edward J Richter, Kalyan Tripathy, Sean M Rafferty, Alexandra M Svoboda, Mariel L Schroeder, Tracy M Burns-Yocum, Karla M Bergonzi, Mark A Chevillet, Emily M Mugler, Adam T Eggebrecht, and Joseph P Culver

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Cytarabine pharmacogenomics and outcomes among children and young adults with acute myeloid leukemia, Richard J Marrero, Geoffrey L Uy, and et al.

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Pooled randomised QUARTET trials assessing effectiveness of a single pill for hypertension, Simone Marschner, Mark D Huffman, Desi Quintans, Jody Ciolino, Abigail Baldridge, Danielle Lazar, Emily R Atkins, Graham S Hillis, Mark R Nelson, Markus Schlaich, Anthony Rodgers, and Clara K Chow

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Meniscal repair in the setting of revision anterior cruciate ligament reconstruction: 6-Year follow-up results from the MARS Cohort, MARS Group, Amanda K Haas, Robert H Brophy, Matthew J Matava, Matthew V Smith, and et al.

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Germline predisposition in multiple myeloma, Fernanda Martins Rodrigues, Yize Li, Erik Storrs, Michael C Wendl, Reyka G Jayasinghe, Mark Fiala, John F DiPersio, Ravi Vij, Li Ding, and et al.

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Non-invasive assessment of vascular damage through pulse wave velocity and superb microvascular imaging in pre-dialysis patients, Julia Martín-Vírgala, Beatriz Martín-Carro, Sara Fernández-Villabrille, Belinda Fernández-Mariño, Elena Astudillo-Cortés, Minerva Rodríguez-García, Carmen Díaz-Corte, José Luis Fernández-Martín, Carlos Gómez-Alonso, Adriana S Dusso, Cristina Alonso-Montes, Manuel Naves-Díaz, Sara Panizo, and Natalia Carrillo-López

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Applying results of extended genotyping to management of positive cervicovaginal human papillomavirus test results: Enduring guidelines, L. Stewart Massad, Megan A. Clarke, Rebecca B. Perkins, Francisco Garcia, David Chelmow, Li C. Cheung, Teresa M. Darragh, Didem Egemen, Thomas S. Lorey, Ritu Nayar, Morgan Newman, Carolann Risley, Robert A. Smith, Nicolas Wentzensen, and Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee

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PTBP1 variants displaying altered nucleocytoplasmic distribution are responsible for a neurodevelopmental disorder with skeletal dysplasia, Aymeric Masson, Catherine Gooch, and et al.

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Role of glucuronoxylomannan and steryl glucosides in protecting against cryptococcosis, Gabriel Soares Matos, Tamara L Doering, and et al.

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Antibiotic de-escalation in the intensive care unit: Rationale and potential strategies, Sarah Singer Matuszak, Lauren Kolodziej, Scott Micek, and Marin Kollef

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Vaccination against influenza viruses annually: Renewing or narrowing the protective shield?, Hanover C Matz and Ali H Ellebedy

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Acinetobacter phages use distinct strategies to breach the capsule barrier, Alexis J. McCalla, Forrest C. Walker, Fabiana Bisaro, Miguel Rodriguez-Anavitate, Anna Johannesman, Gisela Di Venanzio, Mario F. Feldman, and Michele LeRoux

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Social anxiety, negative affect, and hearing difficulties in adults, Katrina Kate S. McClannahan, Sarah McConkey, Julia M Levitan, Thomas L Rodebaugh, and Jonathan E Peelle

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Exposure to household air pollution from biomass cooking and severe pneumonia in infants, John P McCracken, Lindsay J Underhill, and et al.

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Utility of the US Preventive Services Task Force for preeclampsia risk assessment and aspirin prophylaxis, Thomas F McElrath, Antonina I Frolova, and et al.

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Spatiotemporal association of coronavirus disease 2019 cases and deaths with exposure to wildfire particulate matter in 2020, Thomas C McHale, David R Boulware, Kelly Searle, Leda Kobziar, Phinehas Lampman, Julio C Zuniga-Moya, Ben Papadopoulos, Andrej Spec, Naomi E Hauser, and George R Thompson

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Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies, Peter R. McIlroy, Zhuoming Liu, Sean Whelan, and et al.

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Intrinsic adaptive plasticity in mouse and human sensory neurons, Lisa A McIlvried, John Smith Del Rosario, Melanie Y Pullen, Andi Wangzhou, Tayler D Sheahan, Andrew J Shepherd, Richard A Slivicki, John A Lemen, Theodore J Price, Bryan A Copits, and Robert W Gereau

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Rapid viral suppression using integrase inhibitors during acute HIV-1 infection, Mehri S McKellar, Jessica R Keys, Lindsey M Filiatreau, Kara S McGee, Joann D Kuruc, Guido Ferrari, David M Margolis, Joseph J Eron, Charles B Hicks, and Cynthia L Gay

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Three dimensional multiscalar neurovascular nephron connectivity map of the human kidney across the lifespan, Liam McLaughlin, Bo Zhang, Siddharth Sharma, Amanda L Knoten, Madhurima Kaushal, Jeffrey M Purkerson, Heidie L Huyck, Gloria S Pryhuber, Joseph P Gaut, and Sanjay Jain

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Safety and efficacy of IV onasemnogene abeparvovec for pediatric patients with spinal muscular atrophy: The phase 3b SMART study, Hugh J. McMillan, Craig M. Zaidman, and et al.

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Targeting fatty acid synthase reduces aortic atherosclerosis and inflammation, Rodrigo Meade, Dina Ibrahim, Connor Engel, Larisa Belaygorod, Batool Arif, Fong-Fu Hsu, Sangeeta Adak, Ryan Catlett, Mingzhou Zhou, Ma Xenia G Ilagan, Clay F Semenkovich, and Mohamed A Zayed

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Recombinant interleukin-7 treatment of refractory refractory Mycobacterium avium complexlung disease (IMPULSE-7): A pilot phase II, single-center, randomized, clinical trial, Carlos Mejia-Chew, Andrej Spec, Andrew H Walton, Alina Ulezko Antonova, Alexandra Dram, Sanjeev Bhalla, Marco Colonna, Michel Morre, and Richard Hotchkiss

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SARS-CoV-2 N protein and anti-spike serologies: Insights into COVID-19 disease severity and mortality-a secondary analysis of the ACTIV-1 trial, Alfredo J Mena Lora, Kimi Enders, Huimin Wu, Luis Parra-Rodriguez, Christopher Palma, Katy Saliba, Sylvain Laverdurre, P Brian Smith, Kevin J Anstrom, Samuel A Bozzette, and William G Powderly

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AAV gene therapy for Duchenne muscular dystrophy: The EMBARK phase 3 randomized trial, Jerry R Mendell, Craig M Zaidman, and et al.

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Thrombotic microangiopathy after kidney transplantation: Insights into genetic etiology and clinical outcomes, Massini Merzkani, Nyein Chann Wai Lynn, Karen Flores, Gaurav Rajashekar, Kristin Progar, Rowena Delos Santos, John P Atkinson, Daniel C Brennan, and Anuja Java

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HIV pre-exposure prophylaxis does not increase gonorrhea and chlamydia incidence in young Black and Hispanic men who have sex with men: An observational cohort study, Octavio C Mesner, Rishabh Jain, Aditi Ramakrishnan, Derrick D Matthews, and Jeremy T Goldbach

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Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress in mice, Marwa O Mikati, Petra Erdmann-Gilmore, Rose Connors, Sineadh M Conway, Jim Malone, Justin Woods, Robert W Sprung, Reid R Townsend, and Ream Al-Hasani

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Investigation of lncRNA expression in newly diagnosed multiple myeloma reveals a LINC01432-CELF2 axis as an inhibitor of apoptosis, Richa Mishra, Prasanth Thunuguntla, Dhanusha Duraiyan, Alani Perkin, Katelyn Bagwill, Savannah Gonzales, Catheryn Sizemore, Vanessa Brizuela, Jaiyana King, Stephen Daly, Yoon Jae Chang, Mahdote Abebe, Yash Rajana, Kelly Wichmann, Christ Enyan, Shruthi Rangineni, Mark Fiala, Julie Fortier, Reyka Jayasinghe, Mark Schroeder, Li Ding, Ravi Vij, John DiPersio, and Jessica Silva-Fisher

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Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis, Leena B. Mithal, Mark E. Becker, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Aspen Kremer, Surya Pandey, Nicola Lancki, Yawei Li, Yuan Luo, William Grobman, Denise Scholtens, Karen K. Mestan, Patrick C. Seed, and Judd F. Hultquist

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Evolution of the umbilical cord blood proteome across gestational development, Leena B Mithal, Nicola Lancki, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Nathaniel J Rhodes, Byoung-Kyu Cho, William A Grobman, Judd F Hultquist, Denise Scholtens, Karen K Mestan, and Patrick C Seed

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Ablation of the evolutionarily acquired functions of the ATP1B4 gene increases metabolic capacity and reduces obesity, Nikolai N Modyanov, Lucia Russo, Sumona Ghosh Lester, Tamara R Castañeda, Himangi G Marathe, Larisa V Fedorova, Raymond E Bourey, Sonia M Najjar, and Ivana L de la Serna

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ReNeu: A pivotal, phase IIb trial of mirdametinib in adults and children with symptomatic neurofibromatosis type 1-associated plexiform neurofibroma, Christopher L Moertel, Angela C Hirbe, and et al.

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The role of telehealth in sepsis care in rural emergency departments: A qualitative study of emergency department sepsis telehealth user perspectives, Nicholas M. Mohr, Kimberly A. S. Merchant, Brian M. Fuller, Brett Faine, Luke Mack, Amanda Bell, Katie DeJong, Edith A. Parker, Keith Mueller, Elizabeth Chrischilles, Christopher R. Carpenter, Michael P. Jones, Steven Q. Simpson, and Marcia M. Ward

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A clinical practice guideline for the management of pregnancy alloimmunized to red blood cell antigens, Kenneth J Moise, Jay Malone, and et al.

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Correlation of ultrasound and electrodiagnostic evaluation in ballistic peripheral nerve injuries, Mitchell S. Mologne, Zachary D. Randall, Nathan P. Olafsen, David M. Brogan, and Christopher J. Dy

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Development of intestinal tissue-resident T cells in early-life mice before and after weaning, Catherine Montenegro, Siyuan Ding, Federico Perdomo-Celis, and Manuel A Franco

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The common cold is associated with protection from SARS-CoV-2 infections, Camille M Moore, Katherine Rivera-Spoljaric, and et al.

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Complement activation in secondary thrombotic microangiopathies, Johann Morelle, Fernando Caravaca-Fontan, Fadi Fakhouri, Eleni Frangou, Annette Bruchfeld, Jürgen Floege, Safak Mirioglu, Sarah M Moran, Stefanie Steiger, Kate I Stevens, Onno Y K Teng, Selda Aydin, Anuja Java, Sjoerd A M E G Timmermans, and Andreas Kronbichler

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Thalamic and visual network dysfunction relates to tremor response in thalamic deep brain stimulation, Aimee E Morris, Babatunde Adeyemo, Meghan C Campbell, Abraham Z Snyder, Joel S Perlmutter, Jonathan W Mink, and Scott A Norris

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DNA immunotherapy for recurrent respiratory papillomatosis (RRP): Phase 1/2 study assessing efficacy, safety, and immunogenicity of INO-3107, Matthew P Morrow, Randal C Paniello, and et al.

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Clinical characteristics and real-world outcomes in patients with mucopolysaccharidosis II over 18 years: Final report of the Hunter Outcome Survey, Joseph Muenzer, Jaco Botha, Hernan Amartino, Roberto Giugliani, Paul Harmatz, Christoph Kampmann, Bianca Link, Shuan-Pei Lin, David Molter, Julian Raiman, Maurizio Scarpa, Anna Tylki-Szymańska, Siddharth Jain, David A H Whiteman, and Barbara K Burton

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Soft tissue stabilization of midcarpal Instability in Ehlers-Danlos patients using a cadaveric tendon graft, Mohammed Muneer, Fadi Bouri, Kjell Van Royen, Saif Badran, Jorge I. Quintero, and Tuna Ozyurekoglu

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Mechanisms of photoreceptor protection upon targeting the Nrl-Nr2e3 pathway, Daniel P Murphy, Alexander V Kolesnikov, Cynthia L Montana, Zaid M Khaja, Yu Liu, Vladimir J Kefalov, and Joseph C Corbo

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Pan-cancer single cell transcriptomic clustering reveals heterogeneous CD8+ exhausted T cell populations with different immune checkpoint inhibitor responses, Rui Mu, Rasha Barakat, and David H Gutmann

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Hybrid reference genome assembly for the archetypal Leishmania (Viannia) guyanensis bearing the dsRNA totivirus LRV1, Peter J Myler, Gowthaman Ramasamy, Wesley C Warren, Deborah E Dobson, and Stephen M Beverley

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Association of hyponatremia with outcomes after geriatric trauma: A systematic review and meta-analysis, Ariana Naaseh, Steven Tohmasi, Carrie Stoll, Chongliang Luo, Lauren H Yaeger, Mark H Hoofnagle, Graham A Colditz, and Marguerite W Spruce

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Injured tubular epithelia-derived CCN1 promotes the mobilization of fibroblasts toward injury sites after kidney injury, Tomohiro Nakata, Benjamin D Humphreys, and et al.

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Detection and characterization of Langya virus in Crocidura lasiura (the Ussuri white-toothed shrew), Republic of Korea, Augustine Natasha, Sarah E Pye, Kyungmin Park, Shivani Rajoriya, Intae Yang, Jieun Park, Haryo Seno Pangestu, Jongwoo Kim, Yeonsu Oh, Carolina B López, Jin-Won Song, and Won-Keun Kim

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COVID-19-associated pulmonary aspergillosis in mechanically ventilated patients at 7 US hospitals: Epidemiology and estimated likelihood of invasive pulmonary aspergillosis-Results of the prospective MSG-017 study, M Hong Nguyen, Sixto M Leal, Luis Ostrosky-Zeichner, Andrej Spec, George R Thompson, Thomas F Patterson, John Baddley, Rachel McMullen, Drashti Shah, Cornelius J Clancy, Gerald McGwin, and Peter G Pappas

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Intersection of race and rurality with health care-associated infections and subsequent outcomes, Katelin B Nickel, Hannah Kinzer, Anne M Butler, Karen E Joynt Maddox, Victoria J Fraser, Jason P Burnham, and Jennie H Kwon

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Scoping literature review to identify candidate domains for the OMERACT Systemic Lupus Erythematosus core outcome set, Wils Nielsen, Alfred Kim, and et al.

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Matrix metalloproteinases accelerate pericellular matrix breakdown and disrupt mechanotransduction in osteoarthritis, Jule Nieuwstraten, Rosa Riester, Ulf Krister Hofmann, Farshid Guilak, and Marina Danalache

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Oncology provider and patient perspectives on a cardiovascular health assessment tool used during posttreatment survivorship care in community oncology (results from WF-1804CD): Mixed methods observational study, Chandylen L Nightingale, Maura Kepper, Randi E Foraker, and et al.

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In the mouth or in the gut? Innovation through implementing oral and gastrointestinal health science in chronic pain management, Jo Nijs, Burel R Goodin, and et al.

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The inferred functional connectome underlying circadian synchronization in the mouse suprachiasmatic nucleus, K L Nikhil, Bharat Singhal, Daniel Granados-Fuentes, Jr-Shin Li, István Z Kiss, and Erik D Herzog

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Successful endovascular management of concomitant ischemic stroke, myocardial infarction, and massive pulmonary embolism, Ryan W Nolan, Naganathan B Mani, Amir Ata Rahnemai-Azar, Sriya Kosaraju, Arindam Chatterjee, Jasvindar Singh, and Pavan Kumar Kavali

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Informatics at the frontier of cancer research, Kathleen Noller, Malachi Griffith, Daniel Marcus, and et al.

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Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma, Ruth Nousiainen, Katja Eloranta, Jani Saarela, Antti Hassinen, Tamara J Luck, Stefano Cairo, Emilie Indersie, Swapnil Potdar, Michaela J Feodoroff, Jouko Lohi, Lassi Paavolainen, David B Wilson, Vilja Pietiäinen, Markku Heikinheimo, and Marjut Pihlajoki

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Establishing priority pediatric antimicrobial stewardship interventions in the US: Findings from a Delphi consensus study, Harry Obeng, Emmanuel Tetteh, Sara Malone, Matthew Sattler, Monica Abdelnour, Virginia R McKay, and et al.

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Comparative analysis of HIV data completeness in Haiti's iSanté Plus Electronic Medical Record system across children, adolescents and adults: A cross-sectional evaluation of 2016-2022 data, Beryne Odeny, Jean Guy Honoré, Jean Gabriel Balan, James P Hughes, Bradley Wagenaar, Stephen Gloyd, Kemar Célestin, Marinho Elisma, Kesner Francois, and Nancy Puttkammer

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UBR5 in tumor biology: Exploring mechanisms of immune regulation and possible therapeutic implications in MPNST, Diana Akinyi Odhiambo, Selina Fan, and Angela C Hirbe

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Conservation of cis-regulatory codes over half a billion years of evolution, Yohey Ogawa, Yu Liu, Connie A Myers, Ala Morshedian, Gordon L Fain, Alapakkam P Sampath, and Joseph C Corbo

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Left ventricular hypertrophy among adults in a population-based cohort in Haiti, Anju Ogyu, Lisa de Las Fuentes, Victor G Dávila-Román, and et al.

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A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer's disease, Hamilton Se-Hwee Oh, Yuanyuan Shen, Jigyasha Timsina, Chengran Yang, Daniel Western, Muhammad Ali, Carlos Cruchaga, and et al.

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T helper 2 cell-directed immunotherapy eliminates precancerous skin lesions, Tomonori Oka, Neel S. Raval, Mary Tabacchi, Lynn A. Cornelius, and et al.

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Dietary sources of sodium intake in Nigerian adults: A population-based cross-sectional study, Clementina E Okoro, Erica L Jamro, Guhan Iyer, Mark D Huffman, and et al.

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Implementation of single-pill combination medication for hypertension treatment by nonphysician health care workers at primary healthcare facilities in Nigeria: An explanatory mixed methods study, Emmanuel I Okpetu, Chisom Obiezu-Umeh, Boni M Ale, Abigail S Baldridge, Rosemary C B Okoli, Grace J Shedul, Gabriel L Shedul, Nanna R Ripiye, Ikechukwu A Orji, Lisa R Hirschhorn, Dike B Ojji, Mark D Huffman, and Hypertension Treatment in Nigeria Program Investigators

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Measuring and interpreting individual differences in fetal, infant, and toddler neurodevelopment, Halie A Olson, M Catalina Camacho, Natasha Marrus, and et al.

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Longer scans boost prediction and cut costs in brain-wide association studies, Leon Qi Rong Ooi, Scott Marek, Nico U F Dosenbach, Timothy O Laumann, Evan M Gordon, and et al.

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Tazemetostat, a selective EZH2 inhibitor, in combination with pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma: A phase 1 trial, Peter J Oppelt, Sidharth V Puram, Jingxia Liu, Jessica C Ley, and Douglas Adkins

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Mitomycin-C for HPV-positive and HPV-negative platinum-refractory, recurrent or metastatic head and neck squamous cell carcinoma: A phase 2 trial, Peter Oppelt, Jessica Ley, Christine Auberle, Brendan Knapp, Jesse Zaretsky, Fei Wan, and Douglas Adkins

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First-trimester antibiotic use for urinary tract infection and risk of congenital malformations, Sarah S Osmundson, Katelin B Nickel, Susan M. Shortreed, Sascha Dublin, Dustin Stwalley, Michael J Durkin, Paige D Wartko, John M Sahrmann, Ryan Colvin, and Anne M Butler

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HSP70 is a chaperone for IL-33 activity in chronic airway disease, Omar A. Osorio, Heather E. Raphael, Colin E. Kluender, Ghandi F. Hassan, Lucy S. Cohen, Deborah F. Steinberg, Ella Katz-Kiriakos, Morgan D. Payne, Ethan M. Luo, Jamie L. Hicks, Derek E. Byers, and Jennifer Alexander-Brett

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Plasma p-tau217 and tau-PET predict future cognitive decline among cognitively unimpaired individuals: Implications for clinical trials, Rik Ossenkoppele, Tammie L S Benzinger, Suzanne E Schindler, Randall J Bateman, and et al.

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Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex, Rik Ossenkoppele, Tammy L S Benzinger, and et al.

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PHGDH inhibition and FOXO3 modulation drives PUMA-dependent apoptosis in osteosarcoma, Toshinao Oyama, Caitlyn B Brashears, Richa Rathore, Heather Benect-Hamilton, Katharine E Caldwell, Naomi Dirckx, William G Hawkins, and Brian A Van Tine

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PRIDE-FTG advances academic careers of underrepresented early-stage investigators performing blood disorders research, Betty S Pace, Oluwatoyosi A Onwuemene, Athena Starlard-Davenport, Rhea-Beth Markowitz, Vahé Heboyan, Petar Datsov, and Treva Rice

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Deep learning reveals how cells pull, buckle, and navigate fibrous environments, Abinash Padhi, Arka Daw, Atharva Agashe, Medha Sawhney, Maahi M Talukder, Mehran M H Pour, Mohammad Jafari, Guy M Genin, Farid Alisafaei, Sohan Kale, Anuj Karpatne, and Amrinder S Nain

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Efficacy and safety of zilucoplan in amyotrophic lateral sclerosis: A randomized clinical trial, Sabrina Paganoni, Timothy M Miller, and et al.

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Fate mapping of peripherally-derived macrophages after traumatic brain injury in mice reveals a long-lasting population with a distinct transcriptomic signature, Maria Serena Paladini, Benjamin A Yang, Kristof A Torkenczy, Elma S Frias, Xi Feng, Karen Krukowski, Rene Sit, Maurizio Morri, Wendy Lam, Valentina Pedoia, Stefka Tyanova, Marco Colonna, Amber L Nolan, and Susanna Rosi

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Female mice lacking GluA3 show early onset of hearing loss, cochlear synaptopathy, and afferent terminal swellings in ambient sound levels, Indra Pal, Atri Bhattacharyya, Babak V-Ghaffari, Essence Devine Williams, Maolei Xiao, Mark Allen Rutherford, and María Eulalia Rubio

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Establishment of a reverse genetics system for studying human immune functions in mice, Priya Pal, Shuai Gao, Hongbo Gao, Xiwen Qin, Marina Cella, Qiankun Wang, and Liang Shan

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A phase I dose-escalation study of the HIF-2 alpha inhibitor DFF332 in patients with advanced clear-cell renal cell carcinoma, Sumanta K Pal, Joel Picus, and et al.

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NRF2 immunobiology in cancer: Implications for immunotherapy and therapeutic targeting, Harit Panda, Natalie G Rowland, Caroline M Krall, Brittany M Bowman, Michael B Major, and Paul Zolkind

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BCL-XL protects ASS1-deficient cancers from arginine starvation-induced apoptosis, Prashanta Kumar Panda, Ana Carolina Paschoalini Mafra, Alliny C S Bastos, Li Cao, Maria Serra Bonet, Caitlyn B Brashears, Ethan Yang Chen, Heather M Benedict-Hamilton, William Ehrhardt, John Bomalaski, Carina Dehner, Leonard C Rogers, Toshinao Oyama, and Brian A Van Tine

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Inhibition of soluble epoxide hydrolase reduces inflammation and myocardial injury in arrhythmogenic cardiomyopathy, Dipak Panigrahy, Vinay Penna, Kory Lavine, and et al.

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Predicting acute postsurgical pain in the postanesthesia care unit: Risk tool development and internal validation, Nicholas Papadomanolakis-Pakis, Simon Haroutounian, Johan K. Sørensen, Charlotte Runge, Lone D. Brix, Christian F Christiansen, and Lone Nikolajsen