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Submissions from 2023

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Hydrogel encapsulation of genome-engineered stem cells for long-term self-regulating anti-cytokine therapy, Kelsey H Collins, Lara Pferdehirt, Leila S Saleh, Alireza Savadipour, Luke E Springer, Kristin L Lenz, Dominic M Thompson, Sara J Oswald, Christine T N Pham, and Farshid Guilak

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Synthetic biology design as a paradigm shift toward manufacturing affordable adeno-associated virus gene therapies, Logan Thrasher Collins, Selvarangan Ponnazhagan, and David T Curiel

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The heart of Rett syndrome: A quantitative analysis of cardiac repolarization, Michael P Collins, Mark C Johnson, Robin C Ryther, Judith L Weisenberg, Peter T Heydemann, Colleen M Buhrfiend, William A Scott, Dallas M M Armstrong, Haley M Kern, and Hoang H Nguyen

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RAD51 foci as a biomarker predictive of platinum chemotherapy response in ovarian cancer, Amanda J Compadre, Lillian N van Biljon, Mark C Valentine, Emily Graham, Bisiayo Fashemi, Emilee N Kotnik, Isaac Cooper, Lindsay M Kuroki, Carolyn K McCourt, Andrea R Hagemann, Premal H Thaker, David G Mutch, Matthew A Powell, Lulu Sun, Nima Mosammaparast, Peinan Zhao, Elena Lomonosova, Dineo Khabele, Mary M Mullen, and et al.

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Progressive, edematous plaques, mild pancytopenia, and inflammation, Leigh A Compton, Heather A Jones, Connor A Vinyard, Yi-Shan Lee, Matthew J Walter, and Christine C Yokoyama

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Kappa opioid receptor activation increases thermogenic energy expenditure which drives increased feeding, Aaron L Cone, Kenny K Wu, Alexxai V Kravitz, and Aaron J Norris

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Exercise training to improve brain health in older people living with HIV: Study protocol for a randomized controlled trial, Sarah Cooley, Brittany M Nelson, Alexander Rosenow, Elizabeth Westerhaus, W Todd Cade, Dominic N Reeds, Florin Vaida, Kevin E Yarasheski, Robert H Paul, and Beau M Ances

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Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium, Renan Oliveira Corrêa, José Luís Fachi, Marco Colonna, and et al.

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Genomic patterns of malignant peripheral nerve sheath tumor (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA, Isidro Cortes-Ciriano, Dana C Borcherding, Jeffrey J Szymanski, Angela C Hirbe, and et al.

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Effectiveness and safety of different estradiol regimens in transgender women (TREAT study): Protocol for a randomized controlled trial, Samuel Cortez, Dominic Moog, Christopher Lewis, Kelley Williams, Cynthia Herrick, Melanie Fields, Teddi Gray, Zhaohua Guo, Ginger Nicol, and Thomas Baranski

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In situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy, Sara Corvigno, Premal H Thaker, and et al.

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The complement system and human autoimmune diseases, Samantha L Coss, Danlei Zhou, Gilbert T. Chua, Rabheh Abdul Aziz, Robert P. Hoffman, Yee Ling Wu, Stacy P. Ardoin, John P. Atkinson, and Chack-Yung Yu

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Clinical applications of electrical stimulation for peripheral nerve injury: A systematic review, Meredith C Costello, Emily L Errante, Taylor Smartz, Wilson Z Ray, Allan D Levi, and Stephen Shelby Burks

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Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer, Kelsy C Cotto, Yang-Yang Feng, Avinash Ramu, Megan Richters, Sharon L Freshour, Zachary L Skidmore, Huiming Xia, Joshua F McMichael, Jason Kunisaki, Katie M Campbell, Timothy Hung-Po Chen, Emily B Rozycki, Douglas Adkins, Siddhartha Devarakonda, Sumithra Sankararaman, Yiing Lin, William C Chapman, Christopher A Maher, Vivek Arora, Ramaswamy Govindan, Obi L Griffith, Malachi Griffith, and et al.

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Hematopoietic stem cell mobilization for allogeneic stem cell transplantation by motixafortide, a novel CXCR4 inhibitor, Zachary D Crees, Michael P Rettig, Asad Bashey, Steven M Devine, Samantha Jaglowski, Fei Wan, Amy Zhou, Melinda Harding, Abi Vainstein-Haras, Ella Sorani, Irit Gliko-Kabir, Brenda J Grossman, Peter Westervelt, John F DiPersio, and Geoffrey L Uy

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Innovations in hematopoietic stem-cell mobilization: A review of the novel CXCR4 inhibitor motixafortide, Zachary D. Crees, Michael P. Rettig, and John F. DiPersio

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Motixafortide and G-CSF to mobilize hematopoietic stem cells for autologous transplantation in multiple myeloma: A randomized phase 3 trial, Zachary D Crees, Michael P Rettig, Reyka G Jayasinghe, Keith Stockerl-Goldstein, Feng Gao, Mark A Schroeder, Ravi Vij, John F DiPersio, and et al.

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Neuroinflammation and white matter alterations in occupational manganese exposure assessed by diffusion basis spectrum imaging, Susan R Criswell, Susan Searles Nielsen, Irene M Faust, Joshua S Shimony, Robert L White 3rd, Jason Lenox-Krug, and Brad A Racette

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Robust acoustic trapping and perturbation of single-cell microswimmers illuminate three-dimensional swimming and ciliary coordination, Mingyang Cui, Susan K Dutcher, Philip V Bayly, and J Mark Meacham

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Prevalence, characteristics, and correlates of probable avoidant/restrictive food intake disorder among adult respondents to the National Eating Disorders Association online screen: A cross-sectional study, Laura D'Adamo, Lauren Smolar, Katherine N Balantekin, C Barr Taylor, Denise E Wilfley, and Ellen E Fitzsimmons-Craft

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Venographic classification and long-term surgical treatment outcomes for axillary-subclavian vein thrombosis due to venous thoracic outlet syndrome (Paget-Schroetter syndrome), Esmaeel Reza Dadashzadeh, J. Westley Ohman, Pavan K. Kavali, Karen M. Henderson, Danita M. Goestenkors, and Robert W. Thompson

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Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: A double-blind, randomized, placebo-controlled trial, Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-François Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L Moldawer, Richard Hotchkiss, and Bruno François

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Heterogeneous cardiac sympathetic innervation gradients promote arrhythmogenesis in murine dilated cardiomyopathy, Al-Hassan J Dajani, Carla Valenzuela-Ripoll, Ali Javaheri, and et al.

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Associations between age, sex, APOE genotype, and regional vascular physiology in typically aging adults, Nikou L Damestani, John Jacoby, Shrikanth M Yadav, Allison E Lovely, Aurea Michael, Melissa Terpstra, Marziye Eshghi, Barnaly Rashid, Carlos Cruchaga, David H Salat, and Meher R Juttukonda

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The evolution of primary care telehealth disparities during COVID-19: Retrospective cohort study, Rachel D'Amico, Patrick M Schnell, Randi Foraker, J Nwando Olayiwola, Daniel E Jonas, and Seuli Bose Brill

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Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings, Matthew Dapas, Michelle A. Gill, and et al

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Management of acetaminophen poisoning in the US and Canada: A consensus statement, Richard C Dart, Michael E Mullins, and et al.

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3′-sulfated LewisA/C: An oncofetal epitope associated with metaplastic and oncogenic plasticity of the gastrointestinal foregut, Koushik K Das and Jeffrey W Brown

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MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4γ-dependent transcription of CES enzymes, Ritwik Datta, Mohammad A Gholampour, Christopher D Yang, Regan Volk, Sinan Lin, Michael J Podolsky, Thomas Arnold, Florian Rieder, Balyn W Zaro, Michael Verzi, Richard Lehner, Nada Abumrad, Carlos O Lizama, and Kamran Atabai

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Genomic complexity predicts resistance to endocrine therapy and CDK4/6 inhibition in hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer, Andrew A Davis, Jingqin Luo, Rama Suresh, Foluso O Ademuyiwa, Caron Rigden, Timothy P Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Tracy Summa, Brittney Haas, Shana Thomas, Leonel F Hernandez-Aya, Lindsay L Peterson, Cynthia X Ma, and et al.

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Understanding disruptions in cancer care to reduce increased cancer burden, Kia L Davis, Nicole Ackermann, Lisa M Klesges, Nora Leahy, Callie Walsh-Bailey, Sarah Humble, Bettina Drake, and Vetta L Sanders Thompson

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Locus specific endogenous retroviral expression associated with Alzheimer's disease, Tyson Dawson, Uzma Rentia, Jessie Sanford, Carlos Cruchaga, John S K Kauwe, and Keith A Crandall

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Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein, Ryan B. Day, Julia A. Hickman, Ziheng Xu, Casey Ds Katerndahl, Francesca Ferraro, Sai Makund Ramakrishnan, Petra Erdmann-Gilmore, Robert W. Sprung, Yiling Mi, R. Reid Townsend, Christopher A. Miller, and Timothy J. Ley

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Circadian rhythm disrupting behaviours and cancer outcomes in breast cancer survivors: A systematic review, Kelly D'cunha, Yikyung Park, Melinda M Protani, and Marina M Reeves

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Optimum threshold of the 4Kscore for biopsy in men with negative or indeterminate multiparametric magnetic resonance imaging, Ricardo de Almeida S Jr, Eric H Kim, and et al.

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Loss of chromosome 3q is a prognostic marker in fusion-negative rhabdomyosarcoma, Carina A Dehner, Robert C Bell, Yang Cao, Kevin He, John S A Chrisinger, Amy E Armstrong, Marielle Yohe, Jack Shern, and Angela C Hirbe

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Good manufacturing practice production of CD34+ progenitor-derived NK cells for adoptive immunotherapy in acute myeloid leukemia, P K J D de Jonge, P M M van Hauten, L D Janssen, A L de Goede, M M Berrien-Elliott, J M R van der Meer, C M Mousset, M W H Roeven, M Foster, N Blijlevens, W Hobo, T A Fehniger, J H Jansen, N P M Schaap, and H Dolstra

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Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: A multicenter, open-label, phase Ib/II trial, Macarena I de la Fuente, Brian A Van Tine, and et al.

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Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci, Lisa de Las Fuentes, Karen L. Schwander, Yun Ju Sung, Mary F. Feitosa, Ahn Do, C. Charles Gu, Treva K. Rice, Mary K. Wojczynski, Michael M. Province, Dabeeru C. Rao, and et al.

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Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: A subgroup analysis from the randomized MAPT trial, Julien Delrieu, Bruno Vellas, Sophie Guyonnet, Christelle Cantet, Vitaliy Ovod, Yan Li, James Bollinger, Randall Bateman, Sandrine Andrieu, and MAPT/DSA group

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Personal factors and baseline function in patients undergoing non-operative management for chronic hip-related groin pain: A cross-sectional study, Rebecca D DeMargel, Karen Steger-May, Simon Haroutounian, Patricia Zorn, Abby Cheng, John C Clohisy, and Marcie Harris-Hayes

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The Preserving Kidney Function in Children with CKD (PRESERVE) Study: Rationale, design, and methods, Michelle R Denburg, Vikas Dharnidharka, and et al.

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Ex vivo nonbiomaterial gel-based model for endoscopic training, Ameya Deshmukh, Juan Reyes Genere, and Ahmad Najdat Bazarbashi

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Microbiome-targeting therapies in the neonatal intensive care unit: Safety and efficacy, Anna DeVeaux, Jian Ryou, Gautam Dantas, Barbara B Warner, and Phillip I Tarr

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Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes, Jaigeeth Deveryshetty, Rahul Chadda, Jenna R Mattice, Simrithaa Karunakaran, Michael J Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A J Fitzpatrick, Brian Bothner, and Edwin Antony

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Identification of bradycardia following remdesivir administration through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic Pharmacovigilance Project, Jason M Devgun, Rongmei Zhang, Jeffrey Brent, Paul Wax, Keith Burkhart, Alison Meyn, Sharan Campleman, Stephanie Abston, Kim Aldy, and Toxicology Investigators Consortium FACT Study Group

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Utility of targeted gene sequencing to differentiate myeloid malignancies from other cytopenic conditions, Amy E DeZern, Robert S Fulton, Matthew J Walter, and et al.

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Prevalence of diarrheagenic Escherichia coli and impact on child health in Cap-Haitien, Haiti, Jenna N. Diaz, Lora L. Iannotti, Sherlie Jean Louis Dulience, Sydney Vie, Xuntian Jiang, Vadim Grigura, Jacques Boncy, Francesca J. Marhone Pierre, and F. Matthew Kuhlmann

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Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes, Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, and Farshid Guilak

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The proteome of extracellular vesicles of the lung fluke Paragonimus kellicotti produced in vitro and in the lung cyst, Lucia S Di Maggio, Kerstin Fischer, Devyn Yates, Kurt C Curtis, Bruce A Rosa, John Martin, Petra Erdmann-Gilmore, Robert S W Sprung, Makedonka Mitreva, R Reid Townsend, Gary J Weil, and Peter U Fischer

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Intensive care unit sinks are persistently colonized with multidrug resistant bacteria and mobilizable, resistance-conferring plasmids, Luke Diorio-Toth, Meghan A. Wallace, Christopher W. Farnsworth, Bin Wang, Danish Gul, Jennie H. Kwon, Saadia Andleeb, Carey-Ann D. Burnham, and Gautam Dantas

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Replicative Acinetobacter baumannii strains interfere with phagosomal maturation by modulating the vacuolar pH, Jesus S. Distel, Gisela Di Venanzio, Joseph J. Mackel, David A. Rosen, and Mario F. Feldman

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The relationship of trait-like compassion with epigenetic aging: The population-based prospective Young Finns Study, Henrik Dobewall, Liisa Keltikangas-Järvinen, Saara Marttila, Pashupati P Mishra, Aino Saarinen, C Robert Cloninger, Igor Zwir, Mika Kähönen, Mikko Hurme, Olli Raitakari, Terho Lehtimäki, and Mirka Hintsanen

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Enhanced VWF clearance in low VWF pathogenesis: Limitations of the VWFpp/VWF:Ag ratio and clinical significance, Dearbhla Doherty, Michelle Lavin, Mary Byrne, Margaret Nolan, Jamie M O'Sullivan, Kevin Ryan, Niamh M O'Connell, Sandra L Haberichter, Pamela A Christopherson, Jorge Di Paola, Paula D James, and James S O'Donnell

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Optimized strategy for real-time qPCR detection of Onchocerca volvulus DNA in pooled Simulium sp. blackfly vectors, Mary Doherty, Peter U. Fischer, and et al.

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Factor Xa cleaves SARS-CoV-2 spike protein to block viral entry and infection, Wenjuan Dong, Sean P J Whelan, and et al.

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Reversing dysdynamism to interrupt mitochondrial degeneration in amyotrophic lateral sclerosis, Gerald W Dorn II

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Prognostic significance of early platelet dynamics in Staphylococcus aureus bacteremia, Rachid Douglas-Louis, Mimi Lou, Brian Lee, Emi Minejima, Juliane Bubeck-Wardenburg, and Annie Wong-Beringer

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Proteogenomic insights suggest druggable pathways in endometrial carcinoma, Yongchao Dou, Rita Jui-Hsien Lu, Yige Wu, Matthew A Wyczalkowski, David Mutch, Li Ding, and et al.

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The effects of advanced factor analysis approaches on outcomes in randomised trials for depression: Protocol for secondary analysis of individual participant data, Frank Doyle, David Byrne, Robert M Carney, Pim Cuijpers, Alexandra L Dima, Kenneth Freedland, Suzanne Guerin, David Hevey, Bishember Kathuria, Shane Kelly, Stephen McBride, Emma Wallace, and Fiona Boland

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Definitive treatment and risk of death among men diagnosed with metastatic prostate cancer at the Veterans Health Administration, Bettina F Drake, Saira Khan, Mei Wang, Veronica Hicks, Kate Nichols, Meghan Taylor, Eric H Kim, and Su-Hsin Chang

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Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration, Antoine Drieu, Siling Du, Michal Kipnis, Megan E Bosch, Jasmin Herz, Choonghee Lee, Hong Jiang, Melissa Manis, Jason D Ulrich, Jonathan Kipnis, David M Holtzman, and Maud Gratuze

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Final results from a phase 2b randomized, placebo-controlled clinical trial of RBX2660: A microbiota-based drug for the prevention of recurrent Clostridioides difficile infection, Erik R Dubberke, Robert Orenstein, Sahil Khanna, Beth Guthmueller, and Christine Lee

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Exchanging words: Engaging the challenges of sharing qualitative research data, James M DuBois, Jessica Mozersky, Meredith Parsons, Heidi A Walsh, Annie Friedrich, and Amy Pienta

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Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks, Michal Dudek, Dharshika R J Pathiranage, Beatriz Bano-Otalora, Anna Paszek, Natalie Rogers, Cátia F Gonçalves, Craig Lawless, Dong Wang, Zhuojing Luo, Liu Yang, Farshid Guilak, Judith A Hoyland, and Qing-Jun Meng

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Differential processing of risk and reward in delinquent and non-delinquent youth, Natasha Duell, Michael T Perino, Ethan M McCormick, and Eva H Telzer

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Human deprivation amblyopia: Treatment insights from animal models, Kevin R Duffy, Mark F Bear, Nimesh B Patel, Vallabh E Das, and Lawrence Tychsen

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Staphylococcus aureus breast implant infection isolates display recalcitrance to antibiotic pocket irrigants, Jesus M. Duran Ramirez, Jana Gomez, Blake M. Hanson, Taha Isa, Terence M. Myckatyn, and Jennifer N. Walker

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The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions, Christopher C Dvorak, Jeffrey J Bednarski, and et al.

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Trapeziectomy with ligament reconstruction/ suspensionplasty compared to suture tape suspensionplasty for the surgical treatment of advanced thumb carpometacarpal osteoarthritis, Nishant Dwivedi, Ryan P Calfee, Lindley B Wall, Martin I Boyer, David Brogan, Christopher J Dy, and Charles A Goldfarb

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Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: Results from the PHENOM consortium, Dominic B Dwyer, Ganesh B Chand, Aristeidis Sotiras, and et al.

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Long-term outcomes and molecular correlates of sotorasib efficacy in patients with pretreated KRAS G12C-mutated non-small-cell lung cancer: 2-year analysis of CodeBreaK 100, Grace K Dy, Ramaswamy Govindan, and et al.

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Modulation of TRPV4 protects against degeneration induced by sustained loading and promotes matrix synthesis in the intervertebral disc, Garrett W D Easson, Alireza Savadipour, Akila Anandarajah, Leanne E Iannucci, Spencer P Lake, Farshid Guilak, and Simon Y Tang

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TRPV4 differentially controls inflammatory cytokine networks during static and dynamic compression of the intervertebral disc, Garrett W D Easson, Alireza Savadipour, Christian Gonzalez, Farshid Guilak, and Simon Y Tang

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Participatory logic modeling in a multi-site initiative to advance implementation science, Douglas V Easterling, Rebekah R Jacob, Ross C Brownson, Debra Haire-Joshu, Daniel A Gundersen, Heather Angier, Jennifer E DeVoe, Sonja Likumahuwa-Ackman, Thuy Vu, Russell E Glasgow, and Robert Schnoll

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Multicenter randomized trial of carpal tunnel release with ultrasound guidance versus mini-open technique, Kyle R Eberlin, Benjamin P Amis, Thomas P Berkbigler, Christopher J Dy, Mark D Fischer, James L Gluck, F Thomas D Kaplan, Thomas J McDonald, Larry E Miller, Alexander Palmer, Paul E Perry, Marc E Walker, and James F Watt

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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia, Mohamed Eldeeb, Ouyang Yuan, Nicola Guzzi, Phuong Cao Thi Ngoc, Anna Konturek-Ciesla, Trine A Kristiansen, Sowndarya Muthukumar, Jeffrey Magee, Cristian Bellodi, Joan Yuan, and David Bryder

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SVEP1 is an endogenous ligand for the orphan receptor PEAR1, Jared S Elenbaas, Upasana Pudupakkam, Katrina J Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C Lee, Kendall H Burks, Junedh M Amrute, Robert P Mecham, Carmen M Halabi, Arturo Aliso, Jorge Di Paola, and Nathan O Stitziel

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Rapid and sustained improvements in Generalized Pustular Psoriasis Physician Global Assessment scores with spesolimab for treatment of generalized pustular psoriasis flares in the randomized, placebo-controlled Effisayil 1 study, Boni E Elewski, Mark G Lebwohl, Milan J Anadkat, Jonathan Barker, Kamran Ghoreschi, Shinichi Imafuku, Ulrich Mrowietz, Ling Li, Manuel Quaresma, Christian Thoma, and Hervé Bachelez

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Baseline characteristics of the North American Prodromal Synucleinopathy cohort, Jonathan E Elliott, Jennifer McLeland, Susan R Criswell, Yo-El S Ju, and et al.

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SLC-0111, an inhibitor of carbonic anhydrase IX, attenuates hepatoblastoma cell viability and migration, Katja Eloranta, Marjut Pihlajoki, Emmi Liljeström, Ruth Nousiainen, Tea Soini, Jouko Lohi, Stefano Cairo, David B Wilson, Seppo Parkkila, and Markku Heikinheimo

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Geospatial modelling of lymphatic filariasis and malaria co-endemicity in Nigeria, Obiora A Eneanya, Lisa J Reimer, Peter U Fischer, and Gary J Weil

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Invasive community-onset gram-positive infections from July 2018 through December 2022 at 2 children's hospitals, Eric E Engstrom, Alexander S Plattner, J Chase McNeil, Kristina G Hulten, Patrick J Reich, Mary G Boyle, James J Dunn, Stephanie A Fritz, and Sheldon L Kaplan

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Characteristics associated with noncompliance of current Pitch Smart guidelines in high school baseball pitchers throughout the United States, Brandon J Erickson, Eric N Bowman, Christopher Camp, Michael T Freehill, Matthew V Smith, Nicholas Serio, Hiroaki Ishikawa, Karch Smith, and Peter N Chalmers

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Diagnosis and treatment of fungal infections in lung transplant recipients, Jesus E Escamilla, Spenser E January, and Rodrigo Vazquez Guillamet

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Strengthening implementation guidelines for HIV service delivery: Considerations for future evidence generation and synthesis, Ingrid Eshun-Wilson, Nathan Ford, Aaloke Mody, Laura Beres, Sheree Schwartz, Stefan Baral, and Elvin H. Geng

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Pembrolizumab plus chemotherapy in advanced endometrial cancer, Ramez N Eskander, Premal H Thaker, Matthew A Powell, and et al.

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Language exposure during infancy is negatively associated with white matter microstructure in the arcuate fasciculus, Katiana A Estrada, Sharnya Govindaraj, Hervé Abdi, Luke E Moraglia, Jason J Wolff, Shoba Sreenath Meera, Stephen R Dager, Robert C McKinstry, Martin A Styner, Lonnie Zwaigenbaum, Joseph Piven, Meghan R Swanson, and IBIS Network

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Connective tissue presentation in two families expands the phenotypic spectrum of PYROXD1 disorders, Frances J Evesson, Gregory Dziaduch, Samantha J Bryen, Francesca Moore, Sara Pittman, Beena Devanapalli, Leigh B Waddell, Monique M Ryan, Manoj P Menezes, Conrad C Weihl, Adviye Ayper Tolun, Craig Zaidman, Helen Young, Lesley C Adès, and Sandra T Cooper

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Focused ultrasound-mediated delivery of anti-programmed cell death-ligand 1 antibody to the brain of a porcine model, Siaka Fadera, Chinwendu Chukwu, Andrew H Stark, Yimei Yue, Lu Xu, Chih-Yen Chien, Jinyun Yuan, and Hong Chen

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Propranolol reduces IFN-γ driven PD-L1 immunosuppression and improves anti-tumour immunity in ovarian cancer, M Falcinelli, G Al-Hity, S Baron, M Mampay, M C Allen, M Samuels, W Jones, C Cilibrasi, Renee L Flaherty, G Giamas, P H Thaker, and M S Flint

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Semantic wikis as flexible database interfaces for biomedical applications, Marco Falda, Manfredo Atzori, and Maurizio Corbetta

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Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution, Ryann M Fame, Yong Zhang, Michael J Holtzman, and et al.

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Toward blood-based precision medicine: Identifying age-sex-specific vascular biomarker quantities on circulating vascular cells, Yingye Fang, Ling Chen, and P I Imoukhuede

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Patients with stricturing or penetrating Crohn's disease phenotypes report high disease burden and treatment needs, Yanni Fan, Ling Zhang, Negar Omidakhsh, Rhonda L Bohn, Jennifer S Thompson, Kimberly G Brodovicz, and Parakkal Deepak

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Hyperferritinemic sepsis, macrophage activation syndrome, and mortality in a pediatric research network: A causal inference analysis, Zhenziang Fan, John C Lin, Allan Doctor, and et al.

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Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions, Mina Farag, Wade M Borcherds, Anne Bremer, Tanja Mittag, and Rohit V Pappu

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Utilization of microwave ablation as a novel approach for refractory chylothorax following esophagectomy: A case report, Khashayar Farahnak, Alejandro De Filippis Falcon, Hailey M Shepherd, Carlos J Guevara, Mayank R Patel, G Alexander Patterson, Varun Puri, Daniel Kreisel, and Ruben G Nava

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Characteristics of patients with pulmonary arterial hypertension from an innovative, comprehensive real-world patient data repository, Harrison W Farber, Murali M Chakinala, Michelle Cho, Robert P Frantz, Andrew Frick, Lisa Lancaster, Scott Milligan, Ronald Oudiz, Sumeet Panjabi, Yuen Tsang, and Steven D Nathan

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Blockade of IL-6R prevents preterm birth and adverse neonatal outcomes, Marcelo Farias-Jofre, Valeria Garcia-Flores, Nardhy Gomez-Lopez, and et al.