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Submissions from 2023

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Non-small cell lung cancer epigenomes exhibit altered DNA methylation in smokers and never-smokers, Jennifer A Karlow, Erica C Pehrsson, Xiaoyun Xing, Mark Watson, Siddhartha Devarakonda, Ramaswamy Govindan, and Ting Wang

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3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages, Rowan M Karvas, Joseph E Zemke, Syed Shahzaib Ali, Eric Upton, Eshan Sane, Laura A Fischer, Chen Dong, Kyoung-Mi Park, Brian Chew, Brittany Meyer, Chao Zhou, Sabine Dietmann, Thorold W Theunissen, and et al.

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Computerized electrocardiogram data transformation enables effective algorithmic differentiation of wide QRS complex tachycardias, Anthony H Kashou, Sarah LoCoco, Preet A Shaikh, Bhavesh B Katbamna, Ojasav Sehrawat, Daniel H Cooper, Sandeep S Sodhi, Phillip S Cuculich, Marye J Gleva, Elena Deych, Ruiwen Zhou, Lei Liu, Abhishek J Deshmukh, Samuel J Asirvatham, Peter A Noseworthy, Christopher V DeSimone, and Adam M May

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Understanding misimplementation in U.S. state health departments: An agent-based model, Matt Kasman, Ross A Hammond, Rob Purcell, Louise Farah Saliba, Stephanie Mazzucca-Ragan, Margaret Padek, Peg Allen, Douglas A Luke, Sarah Moreland-Russell, Paul C Erwin, and Ross C Brownson

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Purification of modified mammalian actin isoforms for in vitro reconstitution assays, David J Kast and Silvia Jansen

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Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoids, Jenna M Kastenschmidt, Elizabeth Levendosky, Naresha Saligrama, and et al.

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Remote global radiation oncology education and training: A pathway to increase access to high-quality radiation therapy services in low- and middle-income countries, Awusi Kavuma, Matthew Schmidt, Tianyu Zhao, Hiram Gay, Jeff Michalski, Geoffrey Hugo, Jacaranda van Rheenen, Baozhou Sun, and et al.

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Mucosal and systemic neutralizing antibodies to norovirus induced in infant mice orally inoculated with recombinant rotaviruses, Takahiro Kawagishi, Liliana Sánchez-Tacuba, Ningguo Feng, Veronica P Costantini, Ming Tan, Xi Jiang, Kim Y Green, Jan Vinjé, Siyuan Ding, and Harry B Greenberg

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The evaluation of the delayed swollen breast in patients with a history of breast implants, Grace C Keane, Alexandra M Keane, Ryan Diederich, Kaitlyn Kennard, Eric J Duncavage, and Terence M Myckatyn

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Reducing length of antibiotics for children with ear infections: Protocol for a cluster-randomized trial in the USA, Amy Keith, Timothy C Jenkins, Sonja O'Leary, Amy B Stein, Sophie E Katz, Jason Newland, Deborah J Rinehart, Aiden Gilbert, Sherry Dodd, Cindy M Terrill, and Holly M Frost

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A pentasaccharide for monitoring pharmacodynamic response to gene therapy in GM1 gangliosidosis, Pamela Kell, Rohini Sidhu, Mingxing Qian, Sonali Mishra, Dennis J Dietzen, Jingqin Luo, Jean E Schaffer, Daniel S Ory, Xuntian Jiang, and et al.

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Navigating care for rare diseases: Caregiver and patient advice for families and clinicians managing care for vascular malformations, Anna M Kerr, Christine Bereitschaft, Kayla M Duty, and Bryan A Sisk

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Case Report: Stereotactic body radiation treatment for immunotherapy escaped oligometastatic progression in cutaneous melanoma and Merkel cell carcinoma, Karam Khaddour, Alice Zhou, Omar Butt, Jiayi Huang, and George Ansstas

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Local treatment and treatment-related adverse effects among patients with advanced prostate cancer, Saira Khan, Su-Hsin Chang, Mei Wang, Eric H Kim, Martin W Schoen, Carleena Rocuskie-Marker, and Bettina F Drake

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Molecular imaging of bone metastasis, Eliana Khojasteh, Farrokh Dehdashti, and Monica Shokeen

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Obesity and outcomes of Kawasaki disease and COVID-19-related multisystem inflammatory syndrome in children, Michael Khoury, William B Orr, and et al.

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Momelotinib in myelofibrosis patients with thrombocytopenia: Post hoc analysis from three randomized phase 3 trials, Jean-Jacques Kiladjian, Stephen T. Oh, and et al.

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How does facilitation in healthcare work? Using mechanism mapping to illuminate the black box of a meta-implementation strategy, Amy M Kilbourne, Elvin Geng, Ingrid Eshun-Wilson, Shannon Sweeney, Donna Shelley, Deborah J Cohen, JoAnn E Kirchner, Maria E Fernandez, and Michael L Parchman

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Intrinsic tumor resistance to CAR T cells is a dynamic transcriptional state that is exploitable with low-dose radiation, Alexander B Kim, Ssu-Yu Chou, Solomon Kang, Eric Kwon, Matthew Inkman, Jeff Szymanski, Neal Andruska, Cian Colgan, Jin Zhang, Joanna C Yang, Nathan Singh, and Carl J DeSelm

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ERG K+ channels mediate a major component of action potential repolarization in lymphatic muscle, Hae Jin Kim, Min Li, Emma C Erlich, Gwendalyn J Randolph, and Michael J Davis

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IL-6 selectively suppresses cDC1 specification via C/EBPβ, Sunkyung Kim, Jing Chen, Suin Jo, Feiya Ou, Stephen T Ferris, Tian-Tian Liu, Ray A Ohara, David A Anderson, Renee Wu, Michael Y Chen, William E Gillanders, William E Gillanders, Theresa L Murphy, and Kenneth M Murphy

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MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice, Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Terri A Pietka, Jothilingam Sivapackiam, Sun-Ji Park, Fumihiko Urano, Vijay Sharma, Ying Maggie Chen, and et al.

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An intraoperative telemedicine program to improve perioperative quality measures: The ACTFAST-3 randomized clinical trial, Christopher R King, Stephen Gregory, Bradley A Fritz, Thaddeus P Budelier, Arbi Ben Abdallah, Alex Kronzer, Daniel L Helsten, Brian Torres, Sherry McKinnon, Shreya Goswami, Divya Mehta, Omokhaye Higo, Paul Kerby, Bernadette Henrichs, Mary C Politi, Joanna Abraham, Michael S Avidan, Thomas Kannampallil, and et al.

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Potential uses of AI for perioperative nursing handoffs: A qualitative study, Christopher Ryan King, Ayanna Shambe, and Joanna Abraham

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Complete remission of widely metastatic human epidermal growth factor receptor 2-amplified pancreatic adenocarcinoma after precision immune and targeted therapy with description of sequencing and organoid correlates, Daniel A King, S Peter Goedegebuure, Xiuli Zhang, Jasreet Hundal, Malachi Griffith, William E Gillanders, Haeseong Park, and et al.

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Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages, Rachel L. Kinsella, Jacqueline M. Kimmey, Asya Smirnov, Reilly Woodson, Margaret R. Gaggioli, Sthefany M. Chavez, Darren Kreamalmeyer, and Christina L. Stallings

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Prevalence and trends of advanced HIV disease among antiretroviral therapy-naïve and antiretroviral therapy-experienced patients in South Africa between 2010-2021: A systematic review and meta-analysis, Marcel K Kitenge, Geoffrey Fatti, Ingrid Eshun-Wilson, Omololu Aluko, and Peter Nyasulu

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Axatilimab for chronic graft-versus-host disease after failure of at least two prior systemic therapies: Results of a phase I/II study, Carrie L Kitko, Iskra Pusic, and et al.

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Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families, Brian A Kleiboeker, Cheryl Frankfater, Mary E Davey, and Fong-Fu Hsu

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Magnify is a universal molecular anchoring strategy for expansion microscopy, Aleksandra Klimas, Brendan R Gallagher, Piyumi Wijesekara, Sinda Fekir, Emma F DiBernardo, Zhangyu Cheng, Donna B Stolz, Franca Cambi, Simon C Watkins, Steven L Brody, Amjad Horani, Alison L Barth, Christopher I Moore, Xi Ren, and Yongxin Zhao

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The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations, Erik Klontz, Kow Essuman, Jeffrey Milbrandt, Aaron Diantonio, and et al.

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Isolated, full-thickness proximal rectus femoris injury in competitive athletes: A systematic review of injury characteristics and return to play, Derrick M Knapik, Thomas D Alter, Aravinda Ganapathy, Matthew V Smith, Robert H Brophy, and Matthew J Matava

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Discovery and characterization of a new class of O-linking oligosaccharyltransferases from the Moraxellaceae family, Cory J Knoot, Paeton L Wantuch, Lloyd S Robinson, David A Rosen, Nichollas E Scott, and Christian M Harding

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Strategies to prevent Clostridioides difficile infections in acute-care hospitals: 2022 update, Larry K Kociolek, Dale N Gerding, Ruth Carrico, Philip Carling, Curtis J Donskey, Ghinwa Dumyati, David T Kuhar, Vivian G Loo, Lisa L Maragakis, Monika Pogorzelska-Maziarz, Thomas J Sandora, David J Weber, Deborah Yokoe, and Erik R Dubberke

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Changing severity and epidemiology of adults hospitalized with coronavirus disease 2019 (COVID-19) in the United States after introduction of COVID-19 vaccines, March 2021-August 2022, Noah Kojima, Jennie H Kwon, and et al.

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The pyruvate dehydrogenase complex regulates mitophagic trafficking and protein phosphorylation, Panagiota Kolitsida, Vladimir Nolic, Jianwen Zhou, Michael Stumpe, Natalie M Niemi, Jörn Dengjel, and Hagai Abeliovich

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Prospective role of cefiderocol in the management of carbapenem-resistant Acinetobacter baumannii infections: Review of the evidence, Marin Kollef, Herve Dupont, David E Greenberg, Pierluigi Viale, Roger Echols, Yoshinori Yamano, and David P Nicolau

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Macrocephaly and developmental delay caused by missense variants in RAB5C, Klaas Koop, Weimin Yuan, Bo Zhang, Zachary D Dawson, Anika Lindsey, Huiyan Huang, Dustin Baldridge, Gary A Silverman, Stephen C Pak, Tim Schedl, and et al.

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Supplementary feeding and infection control in pregnant adolescents-A secondary analysis of a randomized trial among malnourished women in Sierra Leone, Aminata S Koroma, Mariama Ellie, Kadiatu Bangura, Per O Iversen, David T Hendrixson, Kevin Stephenson, and Mark J Manary

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Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival, Emilee N Kotnik, Mary M Mullen, Nicholas C Spies, Tiandao Li, Matthew Inkman, Jin Zhang, Fernanda Martins-Rodrigues, Ian S Hagemann, Carolyn K McCourt, Premal H Thaker, Andrea R Hagemann, Matthew A Powell, David G Mutch, Dineo Khabele, Gregory D Longmore, Christopher A Maher, Christopher A Miller, Katherine C Fuh, and et al.

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Treatment and disposal practices of pharmaceutical effluent containing potential antibiotic residues in two states in India and perceptions of various stakeholders on contribution of pharmaceutical effluent to antimicrobial resistance: A qualitative study, Anita Kotwani, Ajita Kapur, Mihir Chauhan, and Sumanth Gandra

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A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia, Sevasti B Koukouritaki, Aye Myat M Thinn, Katrina J Ashworth, Juan Fang, Haley S Slater, Lily M Du, Huong Thi Thu Nguyen, Xavier Pillois, Alan T Nurden, Christopher J Ng, Jorge Di Paola, Jieqing Zhu, and David A Wilcox

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Assessment of antibodies in the upper and lower human respiratory tract at steady state and after respiratory viral infection, Marios Koutsakos, Jackson S Turner, M Cristina Vazquez Guillamet, Daniel Reynolds, Tingting Lei, Derek E Byers, Ali H Ellebedy, and Philip A Mudd

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Reproductive decision making in women with medical comorbidities: A qualitative study, Elena M Kraus, Niraj R Chavan, Victoria Whelan, Jennifer Goldkamp, and James M DuBois

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Preliminary validation of a structural magnetic resonance imaging metric for tracking dementia-related neurodegeneration and future decline, Gavin T Kress, Emily S Popa, Paul M Thompson, Susan Y Bookheimer, Sophia I Thomopoulos, Christopher R K Ching, Hong Zheng, Daniel A Hirsh, David A Merrill, Stella E Panos, Cyrus A Raji, Prabha Siddarth, and Jennifer E Bramen

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Creating research-ready partnerships: The initial development of seven implementation laboratories to advance cancer control, Gina R Kruse, Erica Hale, Justin E Bekelman, Jennifer E DeVoe, Rachel Gold, Peggy A Hannon, Thomas K Houston, Aimee S James, Ashley Johnson, Lisa M Klesges, and Andrea L Nederveld

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Provider beliefs in effectiveness and recommendations for primary HPV testing in 3 health-care systems, Gina R Kruse, Jacquelyn M Lykken, Eric J Kim, Jennifer S Haas, Robin T Higashi, Steven J Atlas, Anne Marie McCarthy, Jasmin A Tiro, Michelle I Silver, Celette S Skinner, and Aruna Kamineni

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CIViCdb 2022: Evolution of an open-access cancer variant interpretation knowledgebase, Kilannin Krysiak, Arpad M Danos, Jason Saliba, Joshua F McMichael, Adam C Coffman, Susanna Kiwala, Erica K Barnell, Lana Sheta, Lynzey Kujan, Shahil Pema, Nicholas C Spies, Kaitlin A Clark, Ajay C Venigalla, Avila Suda, Benjamin J Ainscough, Haolin Shen, Alex R Marr, My H Hoang, Kartik Singhal, Mariam Khanfar, Brian V Li, Katie M Campbell, Kelsy C Cotto, Zachary L Skidmore, Jason R Walker, Malachi Griffith, Obi L Griffith, and et al.

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Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia, Leonard D Kuhrt, Edyta Motta, Nirmeen Elmadany, Hannah Weidling, Raphaela Fritsche-Guenther, Ibrahim E Efe, Olivia Cobb, Jit Chatterjee, Lucy G Boggs, Marina Schnauß, Sebastian Diecke, Marcus Semtner, Corina Anastasaki, David H Gutmann, and Helmut Kettenmann

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Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development, Devesha H Kulkarni, Brigida Rusconi, Alexandria N Floyd, Elisabeth L Joyce, Khushi B Talati, Hrishi Kousik, Dereck Alleyne, Dalia L Harris, Lorena Garnica, Ryan McDonough, Shay S Bidani, Hrishikesh S Kulkarni, Elizabeth P Newberry, Keely G McDonald, and Rodney D Newberry

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Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases, Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, and Niraj H Tolia

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Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups, Nuzulul Kurniansyah, C Charles Gu, and et al.

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A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter, Kelsie M LaBarbera, Carla M Yuede, Hannah M Edwards, Woodrow D Gardiner, John R Cirrito, and et al.

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Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation, Roxane Labrosse, Shalini Shenoy, and et al.

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A Cre-dependent massively parallel reporter assay allows for cell-type specific assessment of the functional effects of non-coding elements in vivo, Tomas Lagunas Jr, Stephen P Plassmeyer, Anthony D Fischer, Ryan Z Friedman, Michael A Rieger, Din Selmanovic, Simona Sarafinovska, Yvette K Sol, Michael J Kasper, Stuart B Fass, Alessandra F Aguilar Lucero, Joon-Yong An, Stephan J Sanders, Barak A Cohen, and Joseph D Dougherty

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Sleep disturbance among adults with overactive bladder: A cross-sectional survey, H H Lai, D Walker, D Elsouda, A Lockefeer, K Gallington, and E D Bacci

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An atlas of healthy and injured cell states and niches in the human kidney, Blue B Lake, Amanda Knoten, Bo Zhang, Diane Salamon, Anitha Vijayan, Eric H Kim, Joseph P Gaut, Sanjay Jain, and et al.

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Higher dose oral fluconazole for the treatment of AIDS-related cryptococcal meningitis (HIFLAC)--Report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group, Umesh G. Lalloo, David B. Clifford, and et al.

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Refractory mogamulizumab-associated rash responding to an oral Janus kinase inhibitor, Carine M Lama, Miguel A Hernandez-Rovira, Neha Mehta-Shah, Aaron Russell, and Amy C M Musiek

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Structural gray matter alterations in glioblastoma and high-grade glioma- A potential biomarker of survival, Bidhan Lamichhane, Patrick H Luckett, Donna Dierker, Ki Yun Park, Harold Burton, Michael Olufawo, Gabriel Trevino, John J Lee, Andy G S Daniel, Carl D Hacker, Daniel S Marcus, Joshua S Shimony, and Eric C Leuthardt

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Healthcare provider perspectives on HIV cure research in Ghana, Helena Lamptey, Benjamin Newcomb, Evelyn Y Bonney, James O Aboagye, Peter Puplampu, Vincent J Ganu, Gloria Ansa, Joseph Oliver-Commey, and George B Kyei

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Influence of genomic landscape on cancer immunotherapy for newly diagnosed ovarian cancer: Biomarker analyses from the IMagyn050 randomized clinical trial, Charles N Landen, Premal H Thaker, and et al.

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Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis-on-a-chip, Wyatt E. Lanik, Cliff J. Luke, Lila S. Nolan, Qingqing Gong, Lauren C. Frazer, Jamie M. Rimer, Sarah E. Gale, Raymond Luc, Shay S. Bidani, Carrie A. Sibbald, Angela N. Lewis, Belgacem Mihi, Pranjal Agrawal, Martin Goree, Marlie Maestas, Elise Hu, David F. Peters, and Misty Good

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Adherence to healthy diet and risk of cardiovascular disease in adult survivors of childhood cancer in the St. Jude Lifetime Cohort: A cross-sectional study, Tuo Lan, Mei Wang, Matthew J Ehrhardt, Shu Jiang, Jennifer Q Lanctot, Gregory T Armstrong, Melissa M Hudson, Graham A Colditz, Leslie L Robison, and Yikyung Park

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Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology, Alex T Larsson, Himanshi Bhatia, Xiaochun Zhang, Daniel Schefer, Kuangying Yang, Yang Lyu, Carina A Dehner, John S A Chrisinger, Kevin He, Angela C Hirbe, and et al.

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The VCAM1-ApoE pathway directs microglial chemotaxis and alleviates Alzheimer's disease pathology, Shun-Fat Lau, Wei Wu, Hiu Yi Wong, Li Ouyang, Yi Qiao, Jiahui Xu, Jessica Hiu-Yan Lau, Carlton Wong, Yuanbing Jiang, David M Holtzman, Amy K Y Fu, and Nancy Y Ip

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A review of technological innovations leading to modern endovascular brain aneurysm treatment, David C Lauzier, Anna L Huguenard, Anja I Srienc, Samuel J Cler, Joshua W Osbun, Arindam R Chatterjee, Ananth K Vellimana, Akash P Kansagra, Colin P Derdeyn, Dewitte T Cross, and Christopher J Moran

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Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass, Lina Lawenius, Carrie Cowardin, Jeffrey I Gordon, and et al.

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Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype, Paige E Lawler, James G Bollinger, Suzanne E Schindler, Cynthia R Hodge, Nicolas J Iglesias, Vishal Krishnan, John B Coulton, Yan Li, David M Holtzman, and Randall J Bateman

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Barriers to and solutions for representative inclusion across the lifespan and in life course research: The need for structural competency highlighted by the COVID-19 pandemic, Madison N LeCroy, Ebony B Carter, Sarah S Farabi, Dominic N Reeds, and et al.

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S-adenosylmethionine and nicotinamide riboside therapy in Arts syndrome: A case report and literature review, Angela Lee, Renatta Knox, Margaret Reynolds, Erin McRoy, and Hoanh Nguyen

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Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: Data from five prospective clinical trials, Christine Lee, Thomas Louie, Lindy Bancke, Beth Guthmueller, Adam Harvey, Paul Feuerstadt, Sahil Khanna, Robert Orenstein, and Erik R Dubberke

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VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway, Chunsik Lee, David M Ornitz, and et al.

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Genotype and clinical characteristics of patients with Wolfram syndrome and WFS1-related disorders, Evan M Lee, Megha Verma, Nila Palaniappan, Emiko M Pope, Sammie Lee, Lindsey Blacher, Pooja Neerumalla, William An, Toko Campbell, Cris Brown, Stacy Hurst, Bess Marshall, Tamara Hershey, Fumihiko Urano, and et al.

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Interrater reliability of motor severity scales for hemifacial spasm, Ha Yeon Lee, Ingyun Park, Minnie P Luu, Jerry Zhao, Jeanne P Vu, Elizabeth Cisneros, Brian D Berman, H A Jinnah, Han-Joon Kim, Catherine Y Liu, Joel S Perlmutter, Sarah Pirio Richardson, Anne Weissbach, Glenn T Stebbins, and David A Peterson

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Both Horatio and Polonius: Innate lymphoid cells in tissue homeostasis and repair, Intelly S Lee and Steven J Van Dyken

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Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice, Jiyeon Lee, Julie M Dimitry, Jong Hee Song, Minsoo Son, Patrick W Sheehan, Melvin W King, G Travis Tabor, Young Ah Goo, Mitchell A Lazar, Leonard Petrucelli, and Erik S Musiek

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Clinical situations for which 3D Printing is considered an appropriate representation or extension of data contained in a medical imaging examination: Vascular conditions, Joonhyuk Lee, Seetharam C Chadalavada, Anish Ghodadra, Arafat Ali, Elsa M Arribas, Leonid Chepelev, Ciprian N Ionita, Prashanth Ravi, Justin R Ryan, Lumarie Santiago, Nicole Wake, Adnan M Sheikh, Frank J Rybicki, and David H Ballard

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Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b, Lindsey A Lee, Samantha K Barrick, Ada E Buvoli, Jonathan Walklate, W Tom Stump, Michael Geeves, Michael J Greenberg, and Leslie A Leinwand

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Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles, Lindsey A. Lee, Samantha K. Barrick, Artur Meller, Jonathan Walklate, Jeffrey M. Lotthammer, Jian Wei Tay, W. Tom Stump, Gregory Bowman, Michael A. Geeves, Michael J. Greenberg, and Leslie A Leinwand

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Air pollution and acute kidney injury in the U.S. Medicare population: A longitudinal cohort study, Whanhee Lee, Ziyad Al-Aly, and et al.

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Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods, Miikael Lehtimäki, Binisha H Mishra, Coral Del-Val, Leo-Pekka Lyytikäinen, Mika Kähönen, C Robert Cloninger, Olli T Raitakari, Reijo Laaksonen, Igor Zwir, Terho Lehtimäki, and Pashupati P Mishra

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Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism, Jamison Leid, Ryan Gray, Peter Rakita, Andrew L Koenig, Rohan Tripathy, James A J Fitzpatrick, Charles Kaufman, Lilianna Solnica-Krezel, and Kory J Lavine

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First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors, Rom Leidner, Kevin Conlon, Douglas G McNeel, Andrea Wang-Gillam, Sumati Gupta, Robert Wesolowski, Monica Chaudhari, Nadia Hassounah, Jong Bong Lee, Lang Ho Lee, Jessica A O'Keeffe, Nancy Lewis, George N Pavlakis, and John A Thompson

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Complete hydatidiform mole with a coexisting viable male fetus detected by cell-free DNA, Mackenzie Lemieux, Lauren Kus, Kali Stewart, Mai He, Jackson Rowe, Matthew Brady, Katherine Bligard, Megan Lawlor, and Jeannie Kelly

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Antidepressant augmentation versus switch in treatment-resistant geriatric depression, Eric J Lenze, Pilar Cristancho, Torie R Gettinger, Emily Lenard, J Philip Miller, Ginger E Nicol, Vy T Pham, Lei Yang, and et al.

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Nutritional considerations for a new era: A CF Foundation position paper, Amanda Leonard, Marina Litvin, and et al.

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Nutritional considerations for a new era: A CF Foundation position paper, Amanda Leonard, Marina Litvin, and et al.

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Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse, Adrien Lesage, Maxime Lorenzini, Sophie Burel, Marine Sarlandie, Floriane Bibault, Cecilia Lindskog, Daniel Maloney, Jonathan R Silva, R Reid Townsend, Jeanne M Nerbonne, and Céline Marionneau

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Structural specializations of the sperm tail, Miguel Ricardo Leung, Jianwei Zeng, Xiangli Wang, Marc C Roelofs, Wei Huang, Riccardo Zenezini Chiozzi, Johannes F Hevler, Albert J R Heck, Susan K Dutcher, Alan Brown, Rui Zhang, and Tzviya Zeev-Ben-Mordehai

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ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms, Wendy Leung, Antoine Simoneau, Sneha Saxena, Jessica Jackson, Parasvi S Patel, Mangsi Limbu, Alessandro Vindigni, and Lee Zou

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Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications, Daniel F Levey, Emma C Johnson, Arpana Agrawal, and et al.

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Identifying and addressing barriers to implementing core electronic health record use metrics for ambulatory care: Virtual consensus conference proceedings, Deborah R. Levy, Amanda J. Moy, Nate Apathy, Julia Adler-Milstein, Lisa Rotenstein, Bidisha Nath, S. Trent Rosenbloom, Thomas Kannampallil, Rebecca G. Mishuris, Aram Alexanian, Amber Sieja, Michelle R. Hribar, Jigar S. Patel, Christine A. Sinsky, and Edward R. Melnick

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Electronic health record data quality assessment and tools: A systematic review, Abigail E Lewis, Nicole Weiskopf, Zachary B Abrams, Randi Foraker, Albert M Lai, Philip R O Payne, and Aditi Gupta

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Association between socioeconomic factors, race, and use of a specialty memory clinic, Abigail Lewis, Aditi Gupta, Inez Oh, Suzanne E. Schindler, Nupur Ghoshal, Zachary Abrams, Randi Foraker, Barbara Joy Snider, John C. Morris, Joyce Balls-Berry, Mahendra Gupta, Philip R. O. Payne, and Albert M. Lai

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GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program, Michael Lewis, Tao Cheng, Moe R Mahjoub, and et al.

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Absolute and relative vaccine effectiveness of primary and booster series of COVID-19 vaccines (mRNA and adenovirus vector) against COVID-19 hospitalizations in the United States, December 2021-April 2022, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.

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A draft human pangenome reference, Wen-Wei Liao, Haley J Abel, Robert S Fulton, Chad Tomlinson, Lucinda L Antonacci-Fulton, Sarah Cody, Allison A Regier, Ting Wang, and et al.

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18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis, Noa Liberman, Eric Lieberman Greer, and et al.

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Comprehensive functional characterization of SGCB coding variants predicts pathogenicity in limb-girdle muscular dystrophy type R4/2E, Chengcheng Li, Jackson Wilborn, Sara Pittman, Jil Daw, Jorge Alonso-Pérez, Jordi Díaz-Manera, Conrad C. Weihl, and Gabe Haller