Alterations in ascending aortic hemodynamics and aortic length correlate with sex-specific thoracic aortic aneurysm dilation and lifespan in a mouse model of severe Marfan syndrome

Authors

• Krashn Kr Dwivedi, Washington University in St. Louis
• Yufan Wu, Washington University in St. Louis
• Marisa S Bazzi, Stanford University
• Hadi Wiputra, University of Minnesota - Twin Cities
• Jacob Rother, Washington University in St. Louis
• James D Quirk, Washington University School of Medicine in St. Louis
• Victor H Barocas, University of Minnesota - Twin Cities
• Jessica E Wagenseil, Washington University in St. Louis

Journal

Computers in Biology and Medicine

Publication Date

4-1-2026

Volume

205

First Page

111594

Document Type

Open Access Publication

DOI

10.1016/j.compbiomed.2026.111594

Rights and Permissions

Dwivedi KK, Wu Y, Bazzi MS, Wiputra H, Rother J, Quirk JD, Barocas VH, Wagenseil JE. Alterations in ascending aortic hemodynamics and aortic length correlate with sex-specific thoracic aortic aneurysm dilation and lifespan in a mouse model of severe Marfan syndrome. Comput Biol Med. 2026 Apr 1;205:111594. doi: 10.1016/j.compbiomed.2026.111594. © 2026 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Recommended Citation

Dwivedi, Krashn Kr; Wu, Yufan; Bazzi, Marisa S; Wiputra, Hadi; Rother, Jacob; Quirk, James D; Barocas, Victor H; and Wagenseil, Jessica E, "Alterations in ascending aortic hemodynamics and aortic length correlate with sex-specific thoracic aortic aneurysm dilation and lifespan in a mouse model of severe Marfan syndrome." Computers in Biology and Medicine. 205, 111594 (2026).
https://digitalcommons.wustl.edu/oa_4/6735

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.