General anesthesia versus conscious sedation for mechanical thrombectomy in patients with acute ischemic stroke in the MOST trial

Authors

• Umeshkumar Athiraman, Washington University School of Medicine in St. Louis
• Akash Roy, Medical University of South Carolina
• Andrew Barreto, University of Texas Health Science Center at Houston
• Joseph Broderick, University of Cincinnati
• Colin Derdeyn, University of Virginia
• Jordan Elm, Medical University of South Carolina
• James C Grotta, Memorial Hermann Hospital
• James Ingles, Medical University of South Carolina
• Achala Vagal, University of Cincinnati
• Max Wintermark, University of Texas MD Anderson Cancer Center
• Opeolu Adeoye, Washington University School of Medicine in St. Louis

Journal

Journal of the American Heart Association

Publication Date

2-17-2026

Volume

15

Issue

4

First Page

e044874

Document Type

Open Access Publication

DOI

10.1161/JAHA.125.044874

Rights and Permissions

Athiraman U, Roy A, Barreto A, Broderick J, Derdeyn C, Elm J, Grotta JC, Ingles J, Vagal A, Wintermark M, Adeoye O. General Anesthesia Versus Conscious Sedation for Mechanical Thrombectomy in Patients With Acute Ischemic Stroke in the MOST Trial. J Am Heart Assoc. 2026 Feb 17;15(4):e044874. doi: 10.1161/JAHA.125.044874. © 2026 The Author(s). Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

Recommended Citation

Athiraman, Umeshkumar; Roy, Akash; Barreto, Andrew; Broderick, Joseph; Derdeyn, Colin; Elm, Jordan; Grotta, James C; Ingles, James; Vagal, Achala; Wintermark, Max; and Adeoye, Opeolu, "General anesthesia versus conscious sedation for mechanical thrombectomy in patients with acute ischemic stroke in the MOST trial." Journal of the American Heart Association. 15, 4. e044874 (2026).
https://digitalcommons.wustl.edu/oa_4/7238

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.