Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer

Authors

Benjamin M Wahle, Washington University School of Medicine in St. Louis
Paul Zolkind, Washington University School of Medicine in St. Louis
Ricardo J Ramirez, Washington University School of Medicine in St. Louis
Zachary L Skidmore, Washington University School of Medicine in St. Louis
Sydney R Anderson, Washington University School of Medicine in St. Louis
Angela Mazul, Washington University School of Medicine in St. Louis
D Neil Hayes, University of Tennessee Health Science Center
Vlad C Sandulache, Baylor College of Medicine
Wade L Thorstad, Washington University School of Medicine in St. Louis
Douglas Adkins, Washington University School of Medicine in St. Louis
Obi L Griffith, Washington University School of Medicine in St. Louis
Malachi Griffith, Washington University School of Medicine in St. Louis
Jose P Zevallos, Washington University School of Medicine in St. Louis

Journal

iScience

Publication Date

5-20-2022

Volume

25

Issue

5

First Page

104216

Document Type

Open Access Publication

DOI

10.1016/j.isci.2022.104216

Rights and Permissions

Wahle BM, Zolkind P, Ramirez RJ, Skidmore ZL, Anderson SR, Mazul A, Hayes DN, Sandulache VC, Thorstad WL, Adkins D, Griffith OL, Griffith M, Zevallos JP. Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer. iScience. 2022 Apr 6;25(5):104216. doi: 10.1016/j.isci.2022.104216. Copyright 2022 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Recommended Citation

Wahle, Benjamin M; Zolkind, Paul; Ramirez, Ricardo J; Skidmore, Zachary L; Anderson, Sydney R; Mazul, Angela; Hayes, D Neil; Sandulache, Vlad C; Thorstad, Wade L; Adkins, Douglas; Griffith, Obi L; Griffith, Malachi; and Zevallos, Jose P, "Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer." iScience. 25, 5. 104216 (2022).
https://digitalcommons.wustl.edu/oa_4/1562

Department

ICTS (Institute of Clinical and Translational Sciences), Otolaryngology

Additional Links

Supplemental material is available for this article at publisher site.