Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment

Authors

Michael Chiorazzi, Yale School of Medicine
Bradley Krasnick, Washington University School of Medicine in St. Louis
Keenan J Robbins, Washington University School of Medicine in St. Louis
Zachary Skidmore, Washington University School of Medicine in St. Louis
Jacqueline Mudd, Washington University School of Medicine in St. Louis
Ye Bi, Washington University School of Medicine in St. Louis
S Peter Goedegebuure, Washington University School of Medicine in St. Louis
Malachi Griffith, Washington University School of Medicine in St. Louis
Obi Griffith, Washington University School of Medicine in St. Louis
Abimbola Oyedeji, Washington University School of Medicine in St. Louis
Ryan C Fields, Washington University School of Medicine in St. Louis
et al.

Journal

Journal for ImmunoTherapy of Cancer

Publication Date

7-1-2023

Volume

11

Issue

7

First Page

e006921

Document Type

Open Access Publication

DOI

10.1136/jitc-2023-006921

Rights and Permissions

Chiorazzi M, Martinek J, Krasnick B, Zheng Y, Robbins KJ, Qu R, Kaufmann G, Skidmore Z, Juric M, Henze LA, Brösecke F, Adonyi A, Zhao J, Shan L, Sefik E, Mudd J, Bi Y, Goedegebuure SP, Griffith M, Griffith O, Oyedeji A, Fertuzinhos S, Garcia-Milian R, Boffa D, Detterbeck F, Dhanasopon A, Blasberg J, Judson B, Gettinger S, Politi K, Kluger Y, Palucka K, Fields RC, Flavell RA. Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment. J Immunother Cancer. 2023 Jul;11(7):e006921. doi: 10.1136/jitc-2023-006921. © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Chiorazzi, Michael; Krasnick, Bradley; Robbins, Keenan J; Skidmore, Zachary; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fields, Ryan C; and et al., "Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment." Journal for ImmunoTherapy of Cancer. 11, 7. e006921 (2023).
https://digitalcommons.wustl.edu/oa_4/2080

Department

ICTS (Institute of Clinical and Translational Sciences)