DELETE ME PLEASE

Jennifer N Walker
Blake M Hanson
Tayler Hunter
Shelby R Simar
Jesus M Duran Ramirez
Chloe L P Obernuefemann
Rajiv P Parikh
Marissa M Tenenbaum
Julie A Margenthaler
Scott J Hultgren
Terence M Myckatyn

Abstract

Bacterial infection is the most common complication following staged post-mastectomy breast reconstruction initiated with a tissue expander (TE). To limit bacterial infection, antibiotic irrigation of the surgical site is commonly performed despite little high-quality data to support this practice. We performed a prospective randomized control trial to compare the impact of saline irrigation alone to a triple antibiotic irrigation regimen (1 g cefazolin, 80 mg gentamicin, and 50,000 units of bacitracin in 500 mL of saline) for breast implant surgery. The microbiome in breasts with cancer (