Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms

Authors

Fan He, Washington University School of Medicine in St. Louis
Angelo Ba Laranjeira, Washington University School of Medicine in St. Louis
Tim Kong, Washington University School of Medicine in St. Louis
Shuyang Lin, Washington University School of Medicine in St. Louis
Katrina J. Ashworth, Washington University School of Medicine in St. Louis
Alice Liu, Washington University School of Medicine in St. Louis
Nina M. Lasky, Washington University School of Medicine in St. Louis
Daniel Ac Fisher, Washington University School of Medicine in St. Louis
Maggie J. Cox, Washington University School of Medicine in St. Louis
Mary C. Fulbright, Washington University School of Medicine in St. Louis
Lilian Antunes-Heck, Washington University School of Medicine in St. Louis
LaYow Yu, Washington University School of Medicine in St. Louis
Molly Brakhane, Washington University School of Medicine in St. Louis
Bei Gao, Washington University School of Medicine in St. Louis
Stephen M. Sykes, Washington University School of Medicine in St. Louis
Angelo D'Alessandro, University of Colorado, Denver
Jorge Di Paola, Washington University School of Medicine in St. Louis
Stephen T. Oh, Washington University School of Medicine in St. Louis

Journal

Journal of Clinical Investigation

Publication Date

2-1-2024

Volume

134

Issue

3

First Page

e172256

Document Type

Open Access Publication

DOI

10.1172/JCI172256

Rights and Permissions

He F, Laranjeira AB, Kong T, Lin S, Ashworth KJ, Liu A, Lasky NM, Fisher DA, Cox MJ, Fulbright MC, Antunes-Heck L, Yu L, Brakhane M, Gao B, Sykes SM, D'Alessandro A, Di Paola J, Oh ST. Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms. J Clin Invest. 2024 Feb 1;134(3):e172256. doi: 10.1172/JCI172256. © 2023, He et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

He, Fan; Laranjeira, Angelo Ba; Kong, Tim; Lin, Shuyang; Ashworth, Katrina J.; Liu, Alice; Lasky, Nina M.; Fisher, Daniel Ac; Cox, Maggie J.; Fulbright, Mary C.; Antunes-Heck, Lilian; Yu, LaYow; Brakhane, Molly; Gao, Bei; Sykes, Stephen M.; D'Alessandro, Angelo; Di Paola, Jorge; and Oh, Stephen T., "Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms." Journal of Clinical Investigation. 134, 3. e172256 (2024).
https://digitalcommons.wustl.edu/oa_4/3065

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.