Genome-wide and targeted CRISPR screens identify RNF213 as a mediator of interferon gamma-dependent pathogen restriction in human cells

Authors

Sumit K Matta, Washington University School of Medicine in St. Louis
Hinissan P Kohio, Washington University School of Medicine in St. Louis
Pallavi Chandra, Washington University School of Medicine in St. Louis
Adam Brown, Broad Institute of Harvard and Massachusetts Institute of Technology
John G Doench, Broad Institute of Harvard and Massachusetts Institute of Technology
Jennifer A Philips, Washington University School of Medicine in St. Louis
Siyuan Ding, Washington University School of Medicine in St. Louis
L David Sibley, Washington University School of Medicine in St. Louis

Journal

Proceedings of the National Academy of Sciences of the United States of America

Publication Date

1-2-2024

Volume

121

Issue

1

First Page

e2315865120

Document Type

Open Access Publication

DOI

10.1073/pnas.2315865120

Rights and Permissions

Matta SK, Kohio HP, Chandra P, Brown A, Doench JG, Philips JA, Ding S, Sibley LD. Genome-wide and targeted CRISPR screens identify RNF213 as a mediator of interferon gamma-dependent pathogen restriction in human cells. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2315865120. doi: 10.1073/pnas.2315865120. Copyright © 2023 the Author(s). Published by PNAS. This article is distributed under Creative Commons Attribution- NonCommercial- NoDerivatives License 4.0 (CC BY- NC- ND).

Recommended Citation

Matta, Sumit K; Kohio, Hinissan P; Chandra, Pallavi; Brown, Adam; Doench, John G; Philips, Jennifer A; Ding, Siyuan; and Sibley, L David, "Genome-wide and targeted CRISPR screens identify RNF213 as a mediator of interferon gamma-dependent pathogen restriction in human cells." Proceedings of the National Academy of Sciences of the United States of America. 121, 1. e2315865120 (2024).
https://digitalcommons.wustl.edu/oa_4/3246

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.