Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein

Authors

Ryan B. Day, Washington University School of Medicine in St. Louis
Julia A. Hickman, Washington University School of Medicine in St. Louis
Ziheng Xu, Washington University School of Medicine in St. Louis
Casey Ds Katerndahl, Washington University School of Medicine in St. Louis
Francesca Ferraro, Washington University School of Medicine in St. Louis
Sai Makund Ramakrishnan, Washington University School of Medicine in St. Louis
Petra Erdmann-Gilmore, Washington University School of Medicine in St. Louis
Robert W. Sprung, Washington University School of Medicine in St. Louis
Yiling Mi, Washington University School of Medicine in St. Louis
R. Reid Townsend, Washington University School of Medicine in St. Louis
Christopher A. Miller, Washington University School of Medicine in St. Louis
Timothy J. Ley, Washington University School of Medicine in St. Louis

Journal

Journal of Clinical Investigation

Publication Date

12-7-2023

Volume

134

Issue

4

First Page

e176311

Document Type

Open Access Publication

DOI

10.1172/JCI176311

Rights and Permissions

Day RB, Hickman JA, Xu Z, Katerndahl CD, Ferraro F, Ramakrishnan SM, Erdmann-Gilmore P, Sprung RW, Mi Y, Townsend RR, Miller CA, Ley TJ. Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein. J Clin Invest. 2023 Dec 7;134(4):e176311. doi: 10.1172/JCI176311. © 2023, Day et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Day, Ryan B.; Hickman, Julia A.; Xu, Ziheng; Katerndahl, Casey Ds; Ferraro, Francesca; Ramakrishnan, Sai Makund; Erdmann-Gilmore, Petra; Sprung, Robert W.; Mi, Yiling; Townsend, R. Reid; Miller, Christopher A.; and Ley, Timothy J., "Proteogenomic analysis reveals cytoplasmic sequestration of RUNX1 by the acute myeloid leukemia-initiating CBFB::MYH11 oncofusion protein." Journal of Clinical Investigation. 134, 4. e176311 (2023).
https://digitalcommons.wustl.edu/oa_4/3368

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.