A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection

Authors

Lucas J Adams, Washington University School of Medicine in St. Louis
Laura A VanBlargan, Washington University School of Medicine in St. Louis
Zhuoming Liu, Washington University School of Medicine in St. Louis
Pavlo Gilchuk, Vanderbilt University
Haiyan Zhao, Washington University School of Medicine in St. Louis
Rita E Chen, Washington University School of Medicine in St. Louis
Saravanan Raju, Washington University School of Medicine in St. Louis
Zhenlu Chong, Washington University School of Medicine in St. Louis
Bradley M Whitener, Washington University School of Medicine in St. Louis
Swathi Shrihari, Washington University School of Medicine in St. Louis
Prashant N Jethva, Washington University in St. Louis
Michael L Gross, Washington University School of Medicine in St. Louis
James E Crowe Jr., Vanderbilt University
Sean P J Whelan, Washington University School of Medicine in St. Louis
Michael S Diamond, Washington University School of Medicine in St. Louis
Daved H Fremont, Washington University School of Medicine in St. Louis

Journal

Cell Reports Medicine

Publication Date

12-19-2023

Volume

4

Issue

12

First Page

101305

Document Type

Open Access Publication

DOI

10.1016/j.xcrm.2023.101305

Rights and Permissions

Adams LJ, VanBlargan LA, Liu Z, Gilchuk P, Zhao H, Chen RE, Raju S, Chong Z, Whitener BM, Shrihari S, Jethva PN, Gross ML, Crowe JE Jr, Whelan SPJ, Diamond MS, Fremont DH. A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection. Cell Rep Med. 2023 Dec 19;4(12):101305. doi: 10.1016/j.xcrm.2023.101305. Copyright 2023 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Recommended Citation

Adams, Lucas J; VanBlargan, Laura A; Liu, Zhuoming; Gilchuk, Pavlo; Zhao, Haiyan; Chen, Rita E; Raju, Saravanan; Chong, Zhenlu; Whitener, Bradley M; Shrihari, Swathi; Jethva, Prashant N; Gross, Michael L; Crowe, James E Jr.; Whelan, Sean P J; Diamond, Michael S; and Fremont, Daved H, "A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection." Cell Reports Medicine. 4, 12. 101305 (2023).
https://digitalcommons.wustl.edu/oa_4/3593

Department

ICTS (Institute of Clinical and Translational Sciences)