A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice

Authors

Kelsey A Toth, Washington University School of Medicine in St. Louis
Erica G Schmitt, Washington University School of Medicine in St. Louis
Ana Kolicheski, Washington University School of Medicine in St. Louis
Zev J Greenberg, Washington University School of Medicine in St. Louis
Elizabeth Levendosky, Washington University School of Medicine in St. Louis
Nermina Saucier, Washington University School of Medicine in St. Louis
Kelsey Trammel, Washington University School of Medicine in St. Louis
Vasileios Oikonomou, National Institute of Allergy and Infectious Diseases
Michail S Lionakis, National Institute of Allergy and Infectious Diseases
Eynav Klechevsky, Washington University School of Medicine in St. Louis
Brian S Kim, Icahn School of Medicine at Mount Sinai
Laura G Schuettpelz, Washington University School of Medicine in St. Louis
Naresha Saligrama, Washington University School of Medicine in St. Louis
Megan A Cooper, Washington University School of Medicine in St. Louis

Journal

Journal of experimental medicine

Publication Date

8-5-2024

Volume

221

Issue

8

First Page

e20232091

Document Type

Open Access Publication

DOI

10.1084/jem.20232091

Rights and Permissions

Kelsey A. Toth, Erica G. Schmitt, Ana Kolicheski, Zev J. Greenberg, Elizabeth Levendosky, Nermina Saucier, Kelsey Trammel, Vasileios Oikonomou, Michail S. Lionakis, Eynav Klechevsky, Brian S. Kim, Laura G. Schuettpelz, Naresha Saligrama, Megan A. Cooper; A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice. J Exp Med 5 August 2024; 221 (8): e20232091. © 2024 Toth et al. Originally published in Journal of Experimental Medicine. doi:https://doi.org/10.1084/jem.20232091. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

Recommended Citation

Toth, Kelsey A; Schmitt, Erica G; Kolicheski, Ana; Greenberg, Zev J; Levendosky, Elizabeth; Saucier, Nermina; Trammel, Kelsey; Oikonomou, Vasileios; Lionakis, Michail S; Klechevsky, Eynav; Kim, Brian S; Schuettpelz, Laura G; Saligrama, Naresha; and Cooper, Megan A, "A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice." Journal of experimental medicine. 221, 8. e20232091 (2024).
https://digitalcommons.wustl.edu/oa_4/3879

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.