Ligand efficacy modulates conformational dynamics of the µ-opioid receptor

Authors

Jiawei Zhao, Tsinghua University
Matthias Elgeti, University of California, Los Angeles
Evan S O'Brien, Stanford University
Cecília P Sár, University of Pecs
Amal Ei Daibani, Washington University School of Medicine in St. Louis
Jie Heng, Tsinghua University
Xiaoou Sun, Tsinghua University
Elizabeth White, Stanford University
Tao Che, Washington University School of Medicine in St. Louis
Wayne L Hubbell, University of California, Los Angeles
Brian K Kobilka, Stanford University
Chunlai Chen, Tsinghua University

Journal

Nature

Publication Date

5-1-2024

Volume

629

Issue

8011

First Page

474

Last Page

480

Document Type

Open Access Publication

DOI

10.1038/s41586-024-07295-2

Rights and Permissions

Zhao, J., Elgeti, M., O’Brien, E.S. et al. Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629, 474–480 (2024). https://doi.org/10.1038/s41586-024-07295-2 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Zhao, Jiawei; Elgeti, Matthias; O'Brien, Evan S; Sár, Cecília P; Ei Daibani, Amal; Heng, Jie; Sun, Xiaoou; White, Elizabeth; Che, Tao; Hubbell, Wayne L; Kobilka, Brian K; and Chen, Chunlai, "Ligand efficacy modulates conformational dynamics of the µ-opioid receptor." Nature. 629, 8011. 474 - 480. (2024).
https://digitalcommons.wustl.edu/oa_4/4056

Additional Links

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