Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy

Authors

Hussein Sultan, Washington University School of Medicine in St. Louis
Yoshiko Takeuchi, Washington University School of Medicine in St. Louis
Jeffrey P Ward, Washington University School of Medicine in St. Louis
Tian-Tian Liu, Washington University School of Medicine in St. Louis
Vladimir Sukhov, Washington University School of Medicine in St. Louis
Yuang Song, Washington University School of Medicine in St. Louis
Samuel Ameh, Washington University School of Medicine in St. Louis
Simone Brioschi, Washington University School of Medicine in St. Louis
Darya Khantakova, Washington University School of Medicine in St. Louis
Cora D Arthur, Washington University School of Medicine in St. Louis
J Michael White, Washington University School of Medicine in St. Louis
Heather Kohlmiller, Washington University School of Medicine in St. Louis
Kathleen C F Sheehan, Washington University School of Medicine in St. Louis
Marco Colonna, Washington University School of Medicine in St. Louis
Kenneth M Murphy, Washington University School of Medicine in St. Louis
Maxim N Artyomov, Washington University School of Medicine in St. Louis
Robert D Schreiber, Washington University School of Medicine in St. Louis
et al.

Journal

Nature

Publication Date

8-1-2024

Volume

632

Issue

8023

First Page

182

Last Page

191

Document Type

Open Access Publication

DOI

10.1038/s41586-024-07752-y

Rights and Permissions

Sultan, H., Takeuchi, Y., Ward, J.P. et al. Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature 632, 182–191 (2024). https://doi.org/10.1038/s41586-024-07752-y This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Sultan, Hussein; Takeuchi, Yoshiko; Ward, Jeffrey P; Liu, Tian-Tian; Sukhov, Vladimir; Song, Yuang; Ameh, Samuel; Brioschi, Simone; Khantakova, Darya; Arthur, Cora D; White, J Michael; Kohlmiller, Heather; Sheehan, Kathleen C F; Colonna, Marco; Murphy, Kenneth M; Artyomov, Maxim N; Schreiber, Robert D; and et al., "Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy." Nature. 632, 8023. 182 - 191. (2024).
https://digitalcommons.wustl.edu/oa_4/4090

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.