A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models

Authors

Maritza Puray-Chavez, Washington University School of Medicine in St. Louis
Jenna E Eschbach, Washington University School of Medicine in St. Louis
Ming Xia, Washington University School of Medicine in St. Louis
Kyle M LaPak, Washington University School of Medicine in St. Louis
Qianzi Zhou, Washington University School of Medicine in St. Louis
Ria Jasuja, Washington University School of Medicine in St. Louis
Jiehong Pan, Washington University School of Medicine in St. Louis
Jian Xu, Washington University School of Medicine in St. Louis
Zixiang Zhou, Washington University School of Medicine in St. Louis
Shawn Mohammed, Washington University School of Medicine in St. Louis
Qibo Wang, Washington University School of Medicine in St. Louis
Dana Q Lawson, Washington University School of Medicine in St. Louis
Sanja Djokic, Washington University School of Medicine in St. Louis
Gaopeng Hou, Washington University School of Medicine in St. Louis
Siyuan Ding, Washington University School of Medicine in St. Louis
Steven L Brody, Washington University School of Medicine in St. Louis
Michael B Major, Washington University School of Medicine in St. Louis
Dennis Goldfarb, Washington University School of Medicine in St. Louis
Sebla B Kutluay, Washington University School of Medicine in St. Louis

Journal

Nature Communications

Publication Date

9-27-2024

Volume

15

Issue

1

First Page

8394

Document Type

Open Access Publication

DOI

10.1038/s41467-024-52803-7

Rights and Permissions

Puray-Chavez, M., Eschbach, J.E., Xia, M. et al. A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models. Nat Commun 15, 8394 (2024). https://doi.org/10.1038/s41467-024-52803-7 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Recommended Citation

Puray-Chavez, Maritza; Eschbach, Jenna E; Xia, Ming; LaPak, Kyle M; Zhou, Qianzi; Jasuja, Ria; Pan, Jiehong; Xu, Jian; Zhou, Zixiang; Mohammed, Shawn; Wang, Qibo; Lawson, Dana Q; Djokic, Sanja; Hou, Gaopeng; Ding, Siyuan; Brody, Steven L; Major, Michael B; Goldfarb, Dennis; and Kutluay, Sebla B, "A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models." Nature Communications. 15, 1. 8394 (2024).
https://digitalcommons.wustl.edu/oa_4/4209

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.