TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

Authors

Francesca Cignarella, Washington University School of Medicine in St. Louis
Fabia Filipello, Washington University School of Medicine in St. Louis
Bryan Bollman, Washington University School of Medicine in St. Louis
Claudia Cantoni, Washington University School of Medicine in St. Louis
Alberto Locca, Washington University School of Medicine in St. Louis
Robert Mikesell, Washington University School of Medicine in St. Louis
Melissa Manis, Washington University School of Medicine in St. Louis
Adiljan Ibrahim, Alector
Li Deng, Washington University School of Medicine in St. Louis
Bruno A Benitez, Washington University School of Medicine in St. Louis
Carlos Cruchaga, Washington University School of Medicine in St. Louis
Danilo Licastro, AREA Science Park
Kathie Mihindukulasuriya, Washington University School of Medicine in St. Louis
Oscar Harari, Washington University School of Medicine in St. Louis
Michael Buckland, University of Sydney
David M Holtzman, Washington University School of Medicine in St. Louis
Arnon Rosenthal, Alector
Tina Schwabe, Alector
Ilaria Tassi, Alector
Laura Piccio, Washington University School of Medicine in St. Louis

Journal

Acta Neuropathologica

Publication Date

10-1-2020

Volume

140

Issue

4

First Page

513

Last Page

534

Document Type

Open Access Publication

DOI

10.1007/s00401-020-02193-z

Rights and Permissions

Cignarella, F., Filipello, F., Bollman, B. et al. TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis. Acta Neuropathol 140, 513–534 (2020). https://doi.org/10.1007/s00401-020-02193-z This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Cignarella, Francesca; Filipello, Fabia; Bollman, Bryan; Cantoni, Claudia; Locca, Alberto; Mikesell, Robert; Manis, Melissa; Ibrahim, Adiljan; Deng, Li; Benitez, Bruno A; Cruchaga, Carlos; Licastro, Danilo; Mihindukulasuriya, Kathie; Harari, Oscar; Buckland, Michael; Holtzman, David M; Rosenthal, Arnon; Schwabe, Tina; Tassi, Ilaria; and Piccio, Laura, "TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis." Acta Neuropathologica. 140, 4. 513 - 534. (2020).
https://digitalcommons.wustl.edu/oa_4/443