Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages

Authors

• Michael D Iglesia, Washington University School of Medicine in St. Louis
• Reyka G Jayasinghe, Washington University School of Medicine in St. Louis
• Siqi Chen, Washington University School of Medicine in St. Louis
• Nadezhda V Terekhanova, Washington University School of Medicine in St. Louis
• John M Herndon, Washington University School of Medicine in St. Louis
• Erik Storrs, Washington University School of Medicine in St. Louis
• Alla Karpova, Washington University School of Medicine in St. Louis
• Daniel Cui Zhou, Washington University School of Medicine in St. Louis
• Nataly Naser Al Deen, Washington University School of Medicine in St. Louis
• Andrew T Shinkle, Washington University School of Medicine in St. Louis
• Rita Jui-Hsien Lu, Washington University School of Medicine in St. Louis
• Wagma Caravan, Washington University School of Medicine in St. Louis
• Andrew Houston, Washington University School of Medicine in St. Louis
• Yanyan Zhao, Washington University School of Medicine in St. Louis
• Kazuhito Sato, Washington University School of Medicine in St. Louis
• Preet Lal, Washington University School of Medicine in St. Louis
• Cherease Street, Washington University School of Medicine in St. Louis
• Fernanda Martins Rodrigues, Washington University School of Medicine in St. Louis
• Austin N Southard-Smith, Washington University School of Medicine in St. Louis
• André Luiz N Targino da Costa, Washington University School of Medicine in St. Louis
• Houxiang Zhu, Washington University School of Medicine in St. Louis
• Chia-Kuei Mo, Washington University School of Medicine in St. Louis
• Lisa Crowson, Washington University School of Medicine in St. Louis
• Robert S Fulton, Washington University School of Medicine in St. Louis
• Matthew A Wyczalkowski, Washington University School of Medicine in St. Louis
• Catrina C Fronick, Washington University School of Medicine in St. Louis
• Lucinda A Fulton, Washington University School of Medicine in St. Louis
• Hua Sun, Washington University School of Medicine in St. Louis
• Sherri R Davies, Washington University School of Medicine in St. Louis
• Elizabeth L Appelbaum, Washington University School of Medicine in St. Louis
• Sara E Chasnoff, Washington University School of Medicine in St. Louis
• Madelyn Carmody, Washington University School of Medicine in St. Louis
• Candace Brooks, Washington University School of Medicine in St. Louis
• Ruiyang Liu, Washington University School of Medicine in St. Louis
• Michael C Wendl, Washington University School of Medicine in St. Louis
• Clara Oh, Washington University School of Medicine in St. Louis
• Diane Bender, Washington University School of Medicine in St. Louis
• Carlos Cruchaga, Washington University School of Medicine in St. Louis
• Oscar Harari, Washington University School of Medicine in St. Louis
• Andrea Bredemeyer, Washington University School of Medicine in St. Louis
• Kory Lavine, Washington University School of Medicine in St. Louis
• Ron Bose, Washington University School of Medicine in St. Louis
• Julie Margenthaler, Washington University School of Medicine in St. Louis
• Jason M Held, Washington University School of Medicine in St. Louis
• Samuel Achilefu, Washington University School of Medicine in St. Louis
• Foluso Ademuyiwa, Washington University School of Medicine in St. Louis
• Rebecca Aft, Washington University School of Medicine in St. Louis
• Cynthia Ma, Washington University School of Medicine in St. Louis
• Graham A Colditz, Washington University School of Medicine in St. Louis
• Stephen T Oh, Washington University School of Medicine in St. Louis
• James Fitzpatrick, Washington University School of Medicine in St. Louis
• Kooresh I Shoghi, Washington University School of Medicine in St. Louis
• Milan G Chheda, Washington University School of Medicine in St. Louis
• Deborah J Veis, Washington University School of Medicine in St. Louis
• Feng Chen, Washington University School of Medicine in St. Louis
• Ryan C Fields, Washington University School of Medicine in St. Louis
• William E Gillanders, Washington University School of Medicine in St. Louis
• Li Ding, Washington University School of Medicine in St. Louis
• et al.

Journal

Nature Cancer

Publication Date

11-1-2024

Volume

5

Issue

11

First Page

1713

Last Page

1736

Document Type

Open Access Publication

DOI

10.1038/s43018-024-00773-6

Rights and Permissions

Iglesia, M.D., Jayasinghe, R.G., Chen, S. et al. Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages. Nat Cancer 5, 1713–1736 (2024). https://doi.org/10.1038/s43018-024-00773-6 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Recommended Citation

Iglesia, Michael D; Jayasinghe, Reyka G; Chen, Siqi; Terekhanova, Nadezhda V; Herndon, John M; Storrs, Erik; Karpova, Alla; Zhou, Daniel Cui; Naser Al Deen, Nataly; Shinkle, Andrew T; Lu, Rita Jui-Hsien; Caravan, Wagma; Houston, Andrew; Zhao, Yanyan; Sato, Kazuhito; Lal, Preet; Street, Cherease; Martins Rodrigues, Fernanda; Southard-Smith, Austin N; Targino da Costa, André Luiz N; Zhu, Houxiang; Mo, Chia-Kuei; Crowson, Lisa; Fulton, Robert S; Wyczalkowski, Matthew A; Fronick, Catrina C; Fulton, Lucinda A; Sun, Hua; Davies, Sherri R; Appelbaum, Elizabeth L; Chasnoff, Sara E; Carmody, Madelyn; Brooks, Candace; Liu, Ruiyang; Wendl, Michael C; Oh, Clara; Bender, Diane; Cruchaga, Carlos; Harari, Oscar; Bredemeyer, Andrea; Lavine, Kory; Bose, Ron; Margenthaler, Julie; Held, Jason M; Achilefu, Samuel; Ademuyiwa, Foluso; Aft, Rebecca; Ma, Cynthia; Colditz, Graham A; Oh, Stephen T; Fitzpatrick, James; Shoghi, Kooresh I; Chheda, Milan G; Veis, Deborah J; Chen, Feng; Fields, Ryan C; Gillanders, William E; Ding, Li; and et al., "Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages." Nature Cancer. 5, 11. 1713 - 1736. (2024).
https://digitalcommons.wustl.edu/oa_4/4560

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.