Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling

Authors

• Moydul Islam, Washington University School of Medicine in St. Louis
• David R. Rawnsley, Washington University School of Medicine in St. Louis
• Xiucui Ma, Washington University School of Medicine in St. Louis
• Walter Navid, Washington University School of Medicine in St. Louis
• Chen Zhao, Washington University School of Medicine in St. Louis
• Xumin Guan, Washington University School of Medicine in St. Louis
• Layla Foroughi, Washington University School of Medicine in St. Louis
• John T. Murphy, Washington University School of Medicine in St. Louis
• Honora Navid, Washington University School of Medicine in St. Louis
• Carla J. Weinheimer, Washington University School of Medicine in St. Louis
• Attila Kovacs, Washington University School of Medicine in St. Louis
• Jessica Nigro, Washington University School of Medicine in St. Louis
• Aaradhya Diwan, Washington University School of Medicine in St. Louis
• Ryan P. Chang, Washington University School of Medicine in St. Louis
• Minu Kumari, Washington University School of Medicine in St. Louis
• Martin E. Young, University of Alabama, Birmingham
• Babak Razani, Washington University School of Medicine in St. Louis
• Kenneth B. Margulies, University of Pennsylvania
• Mahmoud Abdellatif, Medical University of Graz
• Simon Sedej, Medical University of Graz
• Ali Javaheri, Washington University School of Medicine in St. Louis
• Douglas F. Covey, Washington University School of Medicine in St. Louis
• Kartik Mani, Washington University School of Medicine in St. Louis
• Abhinav Diwan, Washington University School of Medicine in St. Louis

Journal

Journal of Clinical Investigation

Publication Date

2-11-2025

Volume

135

Issue

7

First Page

e163730

Document Type

Open Access Publication

DOI

10.1172/JCI163730

Rights and Permissions

Islam M, Rawnsley DR, Ma X, Navid W, Zhao C, Guan X, Foroughi L, Murphy JT, Navid H, Weinheimer CJ, Kovacs A, Nigro J, Diwan A, Chang RP, Kumari M, Young ME, Razani B, Margulies KB, Abdellatif M, Sedej S, Javaheri A, Covey DF, Mani K, Diwan A. Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling. J Clin Invest. 2025 Feb 11;135(7):e163730. doi: 10.1172/JCI163730. : © 2025, Islam et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Islam, Moydul; Rawnsley, David R.; Ma, Xiucui; Navid, Walter; Zhao, Chen; Guan, Xumin; Foroughi, Layla; Murphy, John T.; Navid, Honora; Weinheimer, Carla J.; Kovacs, Attila; Nigro, Jessica; Diwan, Aaradhya; Chang, Ryan P.; Kumari, Minu; Young, Martin E.; Razani, Babak; Margulies, Kenneth B.; Abdellatif, Mahmoud; Sedej, Simon; Javaheri, Ali; Covey, Douglas F.; Mani, Kartik; and Diwan, Abhinav, "Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling." Journal of Clinical Investigation. 135, 7. e163730 (2025).
https://digitalcommons.wustl.edu/oa_4/5032

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.