Journal
Translational Psychiatry
Publication Date
7-5-2022
Volume
12
Issue
1
First Page
266
Document Type
Open Access Publication
DOI
10.1038/s41398-022-02029-2
Rights and Permissions
Lai, D., Schwantes-An, TH., Abreu, M. et al. Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. Transl Psychiatry 12, 266 (2022). https://doi.org/10.1038/s41398-022-02029-2 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Recommended Citation
Lai, Dongbing; Agrawal, Arpana; and et al, "Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans." Translational Psychiatry. 12, 1. 266 (2022).
https://digitalcommons.wustl.edu/oa_4/57
858 concordant variants located within gene boundaries
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410 genes included in calculating PRSgene
41398_2022_2029_MOESM3_ESM.docx (104 kB)
675 intergenic concordant variants
41398_2022_2029_MOESM4_ESM.docx (19 kB)
PRSgene calculated using different window sizes
41398_2022_2029_MOESM5_ESM.docx (25 kB)
Gene ontology enrichment analysis results
41398_2022_2029_MOESM6_ESM.docx (25 kB)
Drug target genes
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Negative logP-values of PRSgene using different window sizes to extend gene boundaries
41398_2022_2029_MOESM8_ESM.jpg (630 kB)
Tissue-specific Differentially Expressed Gene enrichment analysis