Amyloidosis of bridging veins is a pathologic feature of Alzheimer's disease

Authors

Leon C D Smyth, Washington University School of Medicine in St. Louis
Daan Verhaege, Washington University School of Medicine in St. Louis
Elio Standen-Bloom, Washington University School of Medicine in St. Louis
Yue Wu, Washington University in St. Louis
Steffen E Storck, Washington University School of Medicine in St. Louis
Pavle Boskovic, Washington University School of Medicine in St. Louis
Benjamin A Plog, Washington University School of Medicine in St. Louis
Tornike Mamuladze, Washington University School of Medicine in St. Louis
Jose A Mazzitelli, Washington University School of Medicine in St. Louis
Zhuoying Wang, Washington University in St. Louis
Daniel D Lee, Washington University School of Medicine in St. Louis
Gwendalyn J Randolph, Washington University School of Medicine in St. Louis
Katherine E Schwetye, Washington University School of Medicine in St. Louis
Song Hu, Washington University in St. Louis
Jonathan Kipnis, Washington University School of Medicine in St. Louis
et al.

Journal

Journal of experimental medicine

Publication Date

2-2-2026

Volume

223

Issue

2

First Page

e20251860

Document Type

Open Access Publication

DOI

10.1084/jem.20251860

Rights and Permissions

Leon C.D. Smyth, Daan Verhaege, Elio Standen-Bloom, Yue Wu, Yiming Gan, Steffen E. Storck, Pavle Boskovic, Benjamin A. Plog, Tornike Mamuladze, Jose A. Mazzitelli, Zhuoying Wang, Daniel D. Lee, Gwendalyn J. Randolph, Antoine Drieu, Katherine E. Schwetye, Song Hu, Daniel S. Reich, Douglas H. Kelley, Rupal I. Mehta, Jonathan Kipnis; Amyloidosis of bridging veins is a pathologic feature of Alzheimer’s disease. J Exp Med 2 February 2026; 223 (2): e20251860. © 2025 Smyth et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20251860.

Recommended Citation

Smyth, Leon C D; Verhaege, Daan; Standen-Bloom, Elio; Wu, Yue; Storck, Steffen E; Boskovic, Pavle; Plog, Benjamin A; Mamuladze, Tornike; Mazzitelli, Jose A; Wang, Zhuoying; Lee, Daniel D; Randolph, Gwendalyn J; Schwetye, Katherine E; Hu, Song; Kipnis, Jonathan; and et al., "Amyloidosis of bridging veins is a pathologic feature of Alzheimer's disease." Journal of experimental medicine. 223, 2. e20251860 (2026).
https://digitalcommons.wustl.edu/oa_4/6049

Department

ICTS (Institute of Clinical and Translational Sciences)