SOX2 regulates foregut squamous epithelial homeostasis and is lost during Barrett's esophagus development

Authors

Ramon U. Jin, Washington University School of Medicine in St. Louis
Yuanwei Xu, Johns Hopkins University
T. Mamie Lih, Johns Hopkins University
Yang-Zhe Huang, Baylor College of Medicine
Toni M. Nittolo, Baylor College of Medicine
Blake E. Sells, Washington University School of Medicine in St. Louis
Olivia M. Dres, Washington University School of Medicine in St. Louis
Jean S. Wang, Washington University School of Medicine in St. Louis
Qing K. Li, Johns Hopkins University
Hui Zhang, Johns Hopkins University
Jason C. Mills, Baylor College of Medicine

Journal

Journal of Clinical Investigation

Publication Date

8-15-2025

Volume

135

Issue

16

First Page

e190374

Document Type

Open Access Publication

DOI

10.1172/JCI190374

Rights and Permissions

Jin RU, Xu Y, Lih TM, Huang YZ, Nittolo TM, Sells BE, Dres OM, Wang JS, Li QK, Zhang H, Mills JC. SOX2 regulates foregut squamous epithelial homeostasis and is lost during Barrett's esophagus development. J Clin Invest. 2025 Jun 19;135(16):e190374. doi: 10.1172/JCI190374. © 2025, Jin et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Jin, Ramon U.; Xu, Yuanwei; Lih, T. Mamie; Huang, Yang-Zhe; Nittolo, Toni M.; Sells, Blake E.; Dres, Olivia M.; Wang, Jean S.; Li, Qing K.; Zhang, Hui; and Mills, Jason C., "SOX2 regulates foregut squamous epithelial homeostasis and is lost during Barrett's esophagus development." Journal of Clinical Investigation. 135, 16. e190374 (2025).
https://digitalcommons.wustl.edu/oa_4/6082

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.