A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

Authors

William C Pilcher, Georgia Institute of Technology
Lijun Yao, Washington University School of Medicine in St. Louis
Yizhe Song, Washington University School of Medicine in St. Louis
Kazuhito Sato, Washington University School of Medicine in St. Louis
Julia T Wang, Washington University School of Medicine in St. Louis
Reyka G Jayasinghe, Washington University School of Medicine in St. Louis
Jennifer A Foltz, Washington University School of Medicine in St. Louis
Mark A Fiala, Washington University School of Medicine in St. Louis
Chiang I-Ling, Washington University School of Medicine in St. Louis
Julie Fortier, Washington University School of Medicine in St. Louis
Michael Slade, Washington University School of Medicine in St. Louis
Stephen T Oh, Washington University School of Medicine in St. Louis
Michael P Rettig, Washington University School of Medicine in St. Louis
John F DiPersio, Washington University School of Medicine in St. Louis
Shaji Kumar, Washington University School of Medicine in St. Louis
Ravi Vij, Washington University School of Medicine in St. Louis
Li Ding, Washington University School of Medicine in St. Louis
et al.

Journal

Nature Cancer

Publication Date

1-1-2026

Volume

7

Issue

1

First Page

224

Last Page

246

Document Type

Open Access Publication

DOI

10.1038/s43018-025-01072-4

Rights and Permissions

Pilcher, W.C., Yao, L., Gonzalez-Kozlova, E. et al. A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma. Nat Cancer 7, 224–246 (2026). https://doi.org/10.1038/s43018-025-01072-4 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Recommended Citation

Pilcher, William C; Yao, Lijun; Song, Yizhe; Sato, Kazuhito; Wang, Julia T; Jayasinghe, Reyka G; Foltz, Jennifer A; Fiala, Mark A; I-Ling, Chiang; Fortier, Julie; Slade, Michael; Oh, Stephen T; Rettig, Michael P; DiPersio, John F; Kumar, Shaji; Vij, Ravi; Ding, Li; and et al., "A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma." Nature Cancer. 7, 1. 224 - 246. (2026).
https://digitalcommons.wustl.edu/oa_4/6341

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.