Intracranial injection of genetically modified, mosquito non-transmissible Zika virus: Safety in primates and ramifications for brain tumor therapy

Authors

Alec J Hirsch, Oregon Health and Science University
Amanda de Andrade Costa, Washington University School of Medicine in St. Louis
Emilie Russler-Germain, Washington University School of Medicine in St. Louis
Ashwani Kesarwani, Washington University School of Medicine in St. Louis
Yuping Li, Washington University School of Medicine in St. Louis
Michael S Diamond, Washington University School of Medicine in St. Louis
Milan G Chheda, Washington University School of Medicine in St. Louis
et al.

Journal

Cell Reports Medicine

Publication Date

12-16-2025

Volume

6

Issue

12

First Page

102509

Document Type

Open Access Publication

DOI

10.1016/j.xcrm.2025.102509

Rights and Permissions

Hirsch AJ, de Andrade Costa A, German C, Parkins CJ, Smith JL, Russler-Germain E, Kesarwani A, Li Y, Carlson VC, Carlson T, McBride JL, Srinivasan S, Lewis AD, Xie X, Shi PY, Diamond MS, Chheda MG. Intracranial injection of genetically modified, mosquito non-transmissible Zika virus: Safety in primates and ramifications for brain tumor therapy. Cell Rep Med. 2025 Dec 16;6(12):102509. doi: 10.1016/j.xcrm.2025.102509. © 2025 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Recommended Citation

Hirsch, Alec J; de Andrade Costa, Amanda; Russler-Germain, Emilie; Kesarwani, Ashwani; Li, Yuping; Diamond, Michael S; Chheda, Milan G; and et al., "Intracranial injection of genetically modified, mosquito non-transmissible Zika virus: Safety in primates and ramifications for brain tumor therapy." Cell Reports Medicine. 6, 12. 102509 (2025).
https://digitalcommons.wustl.edu/oa_4/6360

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.