A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice

Authors

Erica G Schmitt, Washington University School of Medicine in St. Louis
Kelsey A Toth, Washington University School of Medicine in St. Louis
Samuel I Risma, Washington University School of Medicine in St. Louis
Ana Kolicheski, Washington University School of Medicine in St. Louis
Nermina Saucier, Washington University School of Medicine in St. Louis
Rafael J. Feliciano Berríos, Washington University School of Medicine in St. Louis
Zev J. Greenberg, Washington University School of Medicine in St. Louis
Jennifer W. Leiding, Johns Hopkins University
Jack J. Bleesing, University of Cincinnati
Akaluck Thatayatikom, AdventHealth for Children
Laura G. Schuettpelz, Washington University School of Medicine in St. Louis
John R. Edwards, Washington University School of Medicine in St. Louis
Tiphanie P. Vogel, Baylor University
Megan A Cooper, Washington University School of Medicine in St. Louis

Journal

JCI Insight

Publication Date

11-8-2022

Volume

7

Issue

21

First Page

e162695

Document Type

Open Access Publication

DOI

10.1172/jci.insight.162695

Rights and Permissions

Schmitt EG, Toth KA, Risma SI, Kolicheski A, Saucier N, Berríos RJF, Greenberg ZJ, Leiding JW, Bleesing JJ, Thatayatikom A, Schuettpelz LG, Edwards JR, Vogel TP, Cooper MA. A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice. JCI Insight. 2022 Nov 8;7(21):e162695. doi: 10.1172/jci.insight.162695. © 2022, Schmitt et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.

Recommended Citation

Schmitt, Erica G; Toth, Kelsey A; Risma, Samuel I; Kolicheski, Ana; Saucier, Nermina; Berríos, Rafael J. Feliciano; Greenberg, Zev J.; Leiding, Jennifer W.; Bleesing, Jack J.; Thatayatikom, Akaluck; Schuettpelz, Laura G.; Edwards, John R.; Vogel, Tiphanie P.; and Cooper, Megan A, "A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice." JCI Insight. 7, 21. e162695 (2022).
https://digitalcommons.wustl.edu/oa_4/640