Ultrasound applications in the treatment of major depressive disorder: A systematic review of techniques and therapeutic potentials in clinical trials and animal model studies

Authors

• Gansheng Tan, Washington University School of Medicine in St. Louis
• Hong Chen, Washington University School of Medicine in St. Louis
• Eric C Leuthardt, Washington University School of Medicine in St. Louis

Journal

Neuromodulation

Publication Date

2-1-2026

Volume

29

Issue

2

First Page

187

Last Page

204

Document Type

Open Access Publication

DOI

10.1016/j.neurom.2025.08.001

Rights and Permissions

Tan G, Chen H, Leuthardt EC. Ultrasound Applications in the Treatment of Major Depressive Disorder: A Systematic Review of Techniques and Therapeutic Potentials in Clinical Trials and Animal Model Studies. Neuromodulation. 2026 Feb;29(2):187-204. doi: 10.1016/j.neurom.2025.08.001 © 2025 The Authors. Published by Elsevier Inc. on behalf of the International Neuromodulation Society. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Recommended Citation

Tan, Gansheng; Chen, Hong; and Leuthardt, Eric C, "Ultrasound applications in the treatment of major depressive disorder: A systematic review of techniques and therapeutic potentials in clinical trials and animal model studies." Neuromodulation. 29, 2. 187 - 204. (2026).
https://digitalcommons.wustl.edu/oa_4/6533

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.