Differential regulation of cyclic adenosine monophosphate by phosphodiesterase 3A discriminates thrombin-induced protease activated receptor 1- and 4-dependent platelet activation

Authors

• Izabella Andrianova, Washington University School of Medicine in St. Louis
• Abigail Ajanel, Washington University School of Medicine in St. Louis
• Jesse W Rowley, University of Utah
• Darian C Murray, University of Utah
• Yasuhiro Kosaka, University of Utah
• Frederik Denorme, Washington University School of Medicine in St. Louis
• Paul F Bray, University of Utah
• Robert A Campbell, Washington University School of Medicine in St. Louis

Journal

Journal of Thrombosis and Haemostasis

Publication Date

4-1-2026

Volume

24

Issue

4

First Page

1498

Last Page

1510

Document Type

Open Access Publication

DOI

10.1016/j.jtha.2025.12.015

Rights and Permissions

Andrianova I, Ajanel A, Rowley JW, Murray DC, Kosaka Y, Denorme F, Bray PF, Campbell RA. Differential regulation of cyclic adenosine monophosphate by phosphodiesterase 3A discriminates thrombin-induced protease activated receptor 1- and 4-dependent platelet activation. J Thromb Haemost. 2026 Apr;24(4):1498-1510. doi: 10.1016/j.jtha.2025.12.015. © 2026 The Author(s). Published by Elsevier Inc. on behalf of International Society on Thrombosis and Haemostasis. This is an open access article under the CC BYNC license (http://creativecommons.org/licenses/by-nc/4.0/).

Recommended Citation

Andrianova, Izabella; Ajanel, Abigail; Rowley, Jesse W; Murray, Darian C; Kosaka, Yasuhiro; Denorme, Frederik; Bray, Paul F; and Campbell, Robert A, "Differential regulation of cyclic adenosine monophosphate by phosphodiesterase 3A discriminates thrombin-induced protease activated receptor 1- and 4-dependent platelet activation." Journal of Thrombosis and Haemostasis. 24, 4. 1498 - 1510. (2026).
https://digitalcommons.wustl.edu/oa_4/6558

Additional Links

Supplemental material is available for this article at publisher site.