An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins

Authors

• Alireza Ghanbarpour, Washington University School of Medicine in St. Louis
• Bertina Telusma, Massachusetts Institute of Technology
• Barrett M Powell, Massachusetts Institute of Technology
• Jia Jia Zhang, Massachusetts Institute of Technology
• Isabella Bolstad, Massachusetts Institute of Technology
• Carolyn Vargas, University of Graz
• Sandro Keller, University of Graz
• Tania A Baker, Massachusetts Institute of Technology
• Robert T Sauer, Massachusetts Institute of Technology
• Joseph H Davis, Massachusetts Institute of Technology

Journal

The EMBO journal

Publication Date

5-1-2025

Volume

44

Issue

9

First Page

2501

Last Page

2513

Document Type

Open Access Publication

DOI

10.1038/s44318-025-00408-1

Rights and Permissions

Ghanbarpour, A., Telusma, B., Powell, B.M. et al. An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins. EMBO J 44, 2501–2513 (2025). https://doi.org/10.1038/s44318-025-00408-1 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the data associated with this article, unless otherwise stated in a credit line to the data, but does not extend to the graphical or creative elements of illustrations, charts, or figures. This waiver removes legal barriers to the re-use and mining of research data. According to standard scholarly practice, it is recommended to provide appropriate citation and attribution whenever technically possible. Copyright: The Author(s)

Recommended Citation

Ghanbarpour, Alireza; Telusma, Bertina; Powell, Barrett M; Zhang, Jia Jia; Bolstad, Isabella; Vargas, Carolyn; Keller, Sandro; Baker, Tania A; Sauer, Robert T; and Davis, Joseph H, "An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins." The EMBO journal. 44, 9. 2501 - 2513. (2025).
https://digitalcommons.wustl.edu/oa_4/6613

Additional Links

Supplemental material is available for this article at publisher site.