Activation of the human β3 GABAA receptor by combinations of receptor protonation with chemical agonists and gain-of-function mutations

Authors

• Allison L Germann, Washington University School of Medicine in St. Louis
• Spencer R Pierce, Washington University School of Medicine in St. Louis
• Joe Henry Steinbach, Washington University School of Medicine in St. Louis
• Gustav Akk, Washington University School of Medicine in St. Louis

Journal

Biochemical Pharmacology

Publication Date

6-1-2026

Volume

248

First Page

117845

Document Type

Open Access Publication

DOI

10.1016/j.bcp.2026.117845

Rights and Permissions

Germann AL, Pierce SR, Steinbach JH, Akk G. Activation of the human β3 GABAA receptor by combinations of receptor protonation with chemical agonists and gain-of-function mutations. Biochem Pharmacol. 2026 Jun;248:117845. doi: 10.1016/j.bcp.2026.117845. © 2026 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).

Recommended Citation

Germann, Allison L; Pierce, Spencer R; Steinbach, Joe Henry; and Akk, Gustav, "Activation of the human β3 GABAA receptor by combinations of receptor protonation with chemical agonists and gain-of-function mutations." Biochemical Pharmacology. 248, 117845 (2026).
https://digitalcommons.wustl.edu/oa_4/6739