Olutasidenib in recurrent/relapsed locally advanced or metastatic IDH1-mutated chondrosarcoma: Phase 1b/2 trial

Authors

• Robin L Jones, Royal Marsden Hospital/Institute of Cancer Research
• Roman Groisberg, Rutgers Cancer Institute of New Jersey
• Jean-Yves Blay, Centre Léon Bérard
• Howard Colman, University of Utah
• Macarena De La Fuente, University of Miami
• Patricia Roxburgh, University of Glasgow
• Mwe Mwe Chao, Rigel Pharmaceuticals, Inc.
• Hua Tian, Rigel Pharmaceuticals, Inc.
• Florence Duffaud, Aix-Marseille University
• Rastislav Bahleda, Gustave Roussy Cancer Campus
• Brian A Van Tine, Washington University School of Medicine in St. Louis

Journal

Nature Communications

Publication Date

1-29-2026

Volume

17

Issue

1

First Page

2224

Document Type

Open Access Publication

DOI

10.1038/s41467-026-68716-6

Rights and Permissions

Jones, R.L., Groisberg, R., Blay, JY. et al. Olutasidenib in recurrent/relapsed locally advanced or metastatic IDH1-mutated chondrosarcoma: phase 1b/2 trial. Nat Commun 17, 2224 (2026). https://doi.org/10.1038/s41467-026-68716-6 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Recommended Citation

Jones, Robin L; Groisberg, Roman; Blay, Jean-Yves; Colman, Howard; De La Fuente, Macarena; Roxburgh, Patricia; Chao, Mwe Mwe; Tian, Hua; Duffaud, Florence; Bahleda, Rastislav; and Van Tine, Brian A, "Olutasidenib in recurrent/relapsed locally advanced or metastatic IDH1-mutated chondrosarcoma: Phase 1b/2 trial." Nature Communications. 17, 1. 2224 (2026).
https://digitalcommons.wustl.edu/oa_4/6743

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.