Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways

Authors

• Amanda Cimino, Washington University School of Medicine in St. Louis
• Fiona Pat, Washington University School of Medicine in St. Louis
• Omolabake Oyebamiji, Washington University School of Medicine in St. Louis
• Christine T N Pham, Washington University School of Medicine in St. Louis
• Erik D Herzog, Washington University in St. Louis
• Farshid Guilak, Washington University School of Medicine in St. Louis

Journal

Journal of Biological Engineering

Publication Date

5-19-2025

Volume

19

Issue

1

First Page

47

Document Type

Open Access Publication

DOI

10.1186/s13036-025-00519-7

Rights and Permissions

Cimino, A., Pat, F., Oyebamiji, O. et al. Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways. J Biol Eng 19, 47 (2025). https://doi.org/10.1186/s13036-025-00519-7 This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Recommended Citation

Cimino, Amanda; Pat, Fiona; Oyebamiji, Omolabake; Pham, Christine T N; Herzog, Erik D; and Guilak, Farshid, "Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways." Journal of Biological Engineering. 19, 1. 47 (2025).
https://digitalcommons.wustl.edu/oa_4/6773

Department

ICTS (Institute of Clinical and Translational Sciences)

Additional Links

Supplemental material is available for this article at publisher site.